Gene Information

Name : clpE (SSA_0669)
Accession : YP_001034657.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Virulence
Product : ATP dependent protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 651540 - 653810 bp
Length : 2271 bp
Strand : -
Note : GC: 49.01%; Codon Adaptation Index (CAI): 0.786. Helix-turn-helix prediction: AraC. Curator(s): P. Xu

DNA sequence :
ATGCTTTGCCAAAATTGTAAAATCAACGAATCTACGATTCACCTTTATACCAACGTAAATGGCCATAAACAGCAGGTGGA
TTTGTGCCAAAACTGCTACCAAATCATGAAAACAGACCCTGAACATTCCTTGTTCGGCGGAATTGCTAATGCCAACAATC
ATGGAACAGACCCTATTGATGACTTCTTCAACAGCCTCAGCAATTTCCAACAGCCTCAGGAACCAACTACTCCTCCTACC
CAATCTGGCGGAGCCTATGGAGGCGGTGGCGGCTACGGTTCAAATCCTAGCAAGGGTGGTCAGCCTCAGCCAAGTCCGCA
AAAGCCAAAAGGCCTGCTGGAAGAGTTTGGTATCAACGTGACTGAGTTGGCTCGCCGAGGCGAGATTGATCCTGTTATTG
GCCGTGATGAAGAAATCGTCCGTGTCATTGAAATCCTCAACCGCCGCACCAAAAACAATCCTGTTCTCATAGGAGAGCCA
GGAGTCGGAAAAACAGCCGTGGTGGAAGGTCTGGCCCAGAAAATTGTCGATGGTGATGTGCCTCATAAACTCCAAGGCAA
GGAAGTTATCCGCCTAGACGTTGTCAGCTTAGTACAGGGAACTGGTATCCGTGGCCAATTTGAGGAGAGAATGCAGAAGC
TTATAGATGAGATTCGTTCTCGTCAGGATGTCATTCTCTTCATTGATGAAATCCATGAAATTGTCGGAGCAGGCTCTGCT
GGCGATGGCAATATGGACGCTGGGAACATCCTCAAACCAGCTCTGGCTCGCGGAGAACTTCAAATGGTTGGAGCAACCAC
CCTTAATGAATACCGTATCATCGAGAAGGATGCTGCGCTGGAGCGCCGCATGCAGCCGGTTAAGGTAGACGAGCCGACGG
TAGAGGAAACGATTACCATCCTCAAAGGGATTCAGAAAAAATACGAAGACTACCATCACGTCAAGTACACAGATGCAGCC
ATCGAAGCTGCTGCCCTTCTCTCCAACCGCTACATCCAAGACCGCTTCCTGCCAGACAAGGCTATTGACCTCTTGGATGA
GGCTGGATCCAAAATGAATCTGACCCTCAACTTCGTTGATCCCAAGGTCATTGACCAACGTCTGATTGAGGCCGAAAACC
TCAAGGCTCAGGCAACCCGTGACGAAGATTTCGAGAAAGCGGCTTACTTCCGTGACCAGATTGCCAAGTACAAGGAACTC
CAGCAGACAAGTGTACTAGACAAGGATACTCCGATTATCAGCGAGAAAACGATTGAGCACATCGTGGAGCAAAAGACCAA
TATCCCAGTTGGCGATCTCAAAGAAAAGGAACAGTCTCAACTAGTCAATCTCGCTAGCGACTTAAAGGCTCATGTCATCG
GCCAAGACGATGCTGTGGATAAGATTGCCAAGGCCATCCGACGCAACCGGGTCGGACTAGGAAGTCCTAATCGCCCAATC
GGCAGCTTCCTCTTTGTCGGACCTACTGGTGTCGGTAAGACTGAGCTGTCTAAGCAACTAGCCATTGAGCTATTTGGCTC
GGCTGACAGCATGATTCGCTTTGACATGAGTGAATATATGGAAAAACACAGCGTGGCCAAGCTGGTCGGTGCCCCTCCGG
GCTATGTCGGCTATGATGAAGCTGGTCAATTGACTGAGCGCGTCCGTCGTAATCCCTACTCGCTCATTCTGCTGGATGAG
GTGGAAAAGGCCCATCCTGATGTTATGCACATGTTCCTGCAGGTTCTAGATGATGGCCGCCTGACCGATGGTCAAGGCCG
GACTGTCAGCTTCAAAGACACCATTATCATCATGACATCCAATGCCGGAACTGGCAAAGCTGAAGCCAGCGTTGGCTTTG
GAGCAGCGCGTGAAGGCCGCACCAACTCCGTTTTGGGTGAATTGGGTAACTTCTTCAGTCCTGAGTTTATGAATCGCTTT
GACGGCATTATCGAATTCCAGGCGCTCAGCAAGGACAACCTGCTGCAAATCGTCAACCTTATGCTGGACGATGTTAATCA
ACGTTTGGCAACCAACGACATTCATCTGGATGTTACGGAGAAGGTCAAGGAAAAATTGGTTGACCTGGGCTACGATCCAA
AAATGGGGGCTCGCCCACTGCGCCGTACCATTCAGGACCATATCGAAGATGCTATTACTGACTTTTATCTGGAAAATCCA
AGCGAAAAAGATCTCAAAGCTATTATGACCAGCAATGGCAAGATTCTCATCAAGTCAGCCAAGAAAACTGAAAGCACAGA
GTCCGTTCATTCATCTCAAGAAGAAAAATAA

Protein sequence :
MLCQNCKINESTIHLYTNVNGHKQQVDLCQNCYQIMKTDPEHSLFGGIANANNHGTDPIDDFFNSLSNFQQPQEPTTPPT
QSGGAYGGGGGYGSNPSKGGQPQPSPQKPKGLLEEFGINVTELARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLIDEIRSRQDVILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDAA
IEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEL
QQTSVLDKDTPIISEKTIEHIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTERVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFQALSKDNLLQIVNLMLDDVNQRLATNDIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENP
SEKDLKAIMTSNGKILIKSAKKTESTESVHSSQEEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-150 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE YP_001034657.1 ATP dependent protease VFG0080 Protein 0.0 58
clpE YP_001034657.1 ATP dependent protease VFG0079 Protein 1e-160 55