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Name : secA (SSA_0543) Accession : YP_001034538.1 Strain : Streptococcus sanguinis SK36 Genome accession: NC_009009 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 537419 - 539938 bp Length : 2520 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGCGAATATTTTAAAGACTATCATTGAAAATGATAAAGGTGAATTAAGAAAATTAGAAAAAATGGCTGATAAGGTCTT GGCTTATGAAGACGAAATGGCGGCCTTATCTGATGAAGAACTTCAGGCAAAAACAGAAGAATTCAAGAAACGCTATGCTG ATGGCGAAACTTTAGATCAGCTCTTATTTGAAGCTTTTGCGGTTGTCCGTGAAGGAGCTAAGCGAGTGTTGGGCCTTTTC CCATATAAGGTACAGGTTATGGGTGGGATCGTTCTCCATCATGGTGACGTTCCAGAGATGCGTACCGGTGAAGGAAAAAC ATTGACTGCAACAATGCCAGTTTACTTAAATGCCCTTGCAGGCAAAGGTGTGCATGTTGTCACAGTCAACGAATACCTGA CTGAGCGTGACGCGACCGAAATGGGTGAACTCTACTCTTGGCTAGGTCTTTCTGTTGGTATCAATCTGGCGGCTAAGTCT CCAACTGAGAAGAAAGAAGCATATGCTTGCGACATTACCTATTCAACCAATGCTGAAATCGGCTTTGACTATCTGCGTGA TAACATGGTAGTCCGCGCTGAAAACATGGTACAGCGTCCACTCAATTATGCCTTGGTCGATGAGGTGGACTCCATCCTGA TTGACGAAGCTCGGACACCATTGATCGTGTCAGGACCAGTTTCTTCAGATACCAACCAGCTTTATCATATGGCTGACCAC TATGTCAAATCTCTGGATAAGGATGACTACATCATCGATGTTCAGTCTAAGACGATTGGTCTGTCTGACTCAGGTATTGA CAAGGCAGAAAGCTACTTCAAGCTGGACAATCTCTACGATATTGAAAATGTTGCCCTGACTCACTTTATCGACAATGCTC TGCGAGCTAACTACATCATGCTCCTTGACATTGACTATGTGGTCAGTGAAGATCAGGAAATTCTGATTGTTGATCAGTTT ACTGGTCGGACAATGGAAGGACGTCGCTACTCTGACGGTCTCCACCAAGCGATTGAAGCCAAAGAAGGTGTGCCGATTCA GGAAGAAACAAAGACTTCTGCTTCTATTACCTATCAGAACCTCTTCCGTATGTATAAGAAGCTGTCCGGCATGACAGGTA CAGCCAAGACAGAGGAAGAAGAGTTCCGCGAAACTTATAACATCCGTGTTATTCCGATCCCAACCAACCGTCCGGTAGCA CGTATTGACCATTCTGACCTGCTCTACCCAAGTATTGATTCTAAGTTCAAGGCAGTTGTTCAGGATGTTAAAGAGCGTCA TGAAAAAGGCCAGCCAGTTCTGGTCGGTACCGTTGCGGTTGAAACCAGTGATTATATTTCTAAGAAATTGGTAGAAGCTG GGGTTCCTCACGAAGTTCTTAATGCGAAAAACCACTATAAAGAAGCGCAAATTATCATGAATGCTGGCCAACGTGGTGCG GTTACCATTGCGACCAATATGGCTGGACGGGGAACCGACATTAAGTTGGGTGAAGGTGTTCGCGAACTGGGCGGTCTCTG TGTTATCGGTACAGAGCGCCATGAAAGCCGCCGGATTGACAATCAGCTGCGTGGACGTTCAGGCCGTCAGGGTGATCCAG GTGAGTCACAGTTCTACCTGTCACTGGAAGATGAGCTTATGCGCCGCTTTGGGTCAGAGCGTATTAAAGCCCTCTTGGAT CGGATGAACCTTAGCGACGAAGATTCTGTTATCAAGTCTGGCATGCTGACCCGTCAGGTAGAGGCAGCTCAGAAGCGTGT CGAAGGAAATAACTACGATACACGGAAACAAGTCTTGCAGTATGATGATGTGATGCGTGAGCAGCGGGAAATTATCTATG CTGAGCGCCACGATGTCATTACTGCTGACCGTGACCTCAGTCCTGAAATCCATGCTATGATTAAACGGACGATTAACCGT ATCGTTGATGGCAGCAGCCACTCTGATCAGGATGATAAGATTGAAGCGATTTTAAACTTTGCTAAGTATAACTTGGTTTC AGAAGATTCTATTTCTGACAGCGATTTGGAAGGCAAGTCTGACCAAGAAATCAAAGATTATCTGTTTGAACGTGCATTGG AAGTCTATGACAGTCAGATTGCTAAGCTGCGAGACGAAGAAGCAGTGCGTGAATTCCAGAAGGTCTTGATTCTGCGCGTG GTGGACAGCAAGTGGACTGACCATATCGACGCCCTTGACCAGCTGCGCAATGCTGTTGGACTGCGTGGCTATGCACAAAA TAACCCAGTTGTCGAATACCAAGCAGAGAGCTTCCGCATGTTCAACGACATGATTGGCTCCATTGAATTCGATGTGACTC GTCTGATGATGAAAGCGCAGATTCATGAGCAAGAGCGCCCTCGGACCGAGCGGGCTATCAGCACCACAGCTACCCGCAAT ATCTCTGCTAAGGCGCCAAATATGCCTGATAATGCAGACCTGTCTAACGTAAAGAGAAACGACCCTTGTCCATGTGGCTC TGGCAAGAAGTTCAAGAACTGTCACGGCCGTAAAAAGTAA Protein sequence : MANILKTIIENDKGELRKLEKMADKVLAYEDEMAALSDEELQAKTEEFKKRYADGETLDQLLFEAFAVVREGAKRVLGLF PYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALAGKGVHVVTVNEYLTERDATEMGELYSWLGLSVGINLAAKS PTEKKEAYACDITYSTNAEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGPVSSDTNQLYHMADH YVKSLDKDDYIIDVQSKTIGLSDSGIDKAESYFKLDNLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDQEILIVDQF TGRTMEGRRYSDGLHQAIEAKEGVPIQEETKTSASITYQNLFRMYKKLSGMTGTAKTEEEEFRETYNIRVIPIPTNRPVA RIDHSDLLYPSIDSKFKAVVQDVKERHEKGQPVLVGTVAVETSDYISKKLVEAGVPHEVLNAKNHYKEAQIIMNAGQRGA VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGSERIKALLD RMNLSDEDSVIKSGMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAERHDVITADRDLSPEIHAMIKRTINR IVDGSSHSDQDDKIEAILNFAKYNLVSEDSISDSDLEGKSDQEIKDYLFERALEVYDSQIAKLRDEEAVREFQKVLILRV VDSKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAESFRMFNDMIGSIEFDVTRLMMKAQIHEQERPRTERAISTTATRN ISAKAPNMPDNADLSNVKRNDPCPCGSGKKFKNCHGRKK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 2e-148 | 42 |
