Gene Information

Name : leuS (SSA_0289)
Accession : YP_001034296.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 281546 - 284059 bp
Length : 2514 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGAGAAAAGAATGGCTTATTATAATCACAAAGAAATCGAACCCAAGTGGCAGAAATATTGGGCAGAGCACCATACATT
TAAGACAGGTACGGACAAGGACAAGCCTAACTTTTATGCGCTGGACATGTTTCCTTATCCATCAGGAGCGGGACTCCATG
TAGGGCATCCGGAGGGCTACACGGCGACAGATATCCTTAGCCGCTACAAGCGAACTCAGGGCTATAATGTCCTGCATCCT
ATGGGCTGGGATGCCTTTGGTCTGCCAGCTGAGCAATATGCCATGGATACAGGCAATGACCCAGCTGATTTTACAGCGGA
AAACATTGCCAACTTCAAGCGTCAAATCAACGCTCTAGGATTTTCGTATGACTGGGACCGAGAAATCAATACAACTGACC
CTAACTACTATAAGTGGACCCAGTGGATTTTCACAAAGCTTTACGAAAAAGGTCTGGCTTATGAAGCTGAAGTGCCAGTA
AACTGGGTTGAAGAGCTGGGAACGGCTATTGCCAATGAGGAAGTTCTGCCAGATGGCACATCTGAGCGCGGCGGTTATCC
AGTTGTCCGCAAGCCTATGCGTCAGTGGATGCTGAAAATCACAGCCTATGCAGAACGTTTGCTCAATGACTTGGAGGAAC
TGGACTGGCCAGAGTCTATCAAGGATATGCAGCGCAACTGGATCGGCAAGTCAACCGGTGCCAATGTAACCTTCAAGATT
AAGGACACTGACAAGGACTTCACCGTCTTTACGACTCGTCCGGACACCCTTTTTGGTGCGACCTATGCTGTTTTGGCTCC
GGAGCATGCTCTCGTTGATGCCATTACAAGTGCCGAACAAGCCCAAGCAGTTGCAGACTACAAACATGCAGCCAGTCTCA
AATCTGACCTTGCTCGGACTGATTTGGCTAAGGATAAGACTGGTGTCTGGACAGGCGCTTATGCCATCAATCCTGTCAAC
GGCAAGGAAATCCCCATCTGGATTGCCGACTATGTACTTGCAAGCTACGGAACAGGTGCTATCATGGCCGTTCCTGCGCA
TGACGAGCGCGACTGGGAGTTTGCTAAGCAGTTTGACTTGGAGATTATTCCGGTTCTAGAAGGTGGCAATGTTGCTGAAG
CTGCTTATACAGAGGACGGTCCGCACATTAACTCGGGCTTCCTAGATGGCTTGGACAAGGCTGCCGCTATCGACAAGATG
GTTGCTTGGCTGGAAGCAGAAGGTGTCGGAAATGAAAAAGTCACCTATCGCCTGCGCGACTGGCTCTTTAGTCGTCAACG
CTACTGGGGTGAGCCGATTCCAATCATTCATTGGGAGGATGGCACCTCAACAGCTGTTCCTGAAAATGAATTGCCACTTG
TCTTGCCTGTAACCAAGGATATCCGCCCTTCTGGTACTGGTGAAAGTCCTCTGGCCAATTTGACTGACTGGCTGGAAGTG
ACTAGGGAAGATGGTGTTAAAGGACGCCGCGAAACCAACACTATGCCTCAATGGGCTGGTTCCAGCTGGTATTACCTGCG
TTACATTGACCCGCACAACAATGAGAAATTAGCAGACGAAGAACTGCTCAAGGCTTGGCTTCCAGTTGATATTTACATCG
GAGGTGCGGAGCACGCCGTGCTCCATCTTCTCTACGCTCGCTTCTGGCACAAGTTCCTTTATGATATCGGAGTGGTTCCG
ACCAAAGAGCCTTTCCAAAAACTCTTTAACCAAGGGATGATTCTGGGGACTAGCTACCGTGATAGTCGCTGTGCTCTAGT
GGCGACAGACAAGGTGGAAAAACGCGATGGTTCTTTCTTCAATATCGAAACTGGAGAAGAACTGGAGCAAGCGCCTGCTA
AGATGTCTAAGTCTCTGAAGAATGTAGTCAACCCAGACGATGTAGTGGAGCAATATGGTGCCGATACGCTTCGTGTCTAT
GAAATGTTCATGGGGCCGCTGGATGCATCTATCGCTTGGAGCGAAGAAGGGTTAGAAGGCAGCCGTAAGTTCCTTGATCG
GGTTTATCGTCTCTTTAACTCTAAGGAGCTGGTCACTGAAAATAGCGGAGCTTTGGACAAGGTCTACCATGAAACGGTCA
AGTCTGTCACAGAGCAGATTGAGGAGCTCAAGTTTAACACAGCCATTGCCCAGCTCATGATCTTTGTCAATGCAGCCAAC
AAGGAAGAAAAGCTCTATGTCGAATATGCCAAAGGCTTTATCCAATTGCTGGCGCCTTTTGCACCGCACTTGGCTGAAGA
ACTCTGGCAGGCAGTCGCTCAAACTGGCGAGAGCATTTCCTATGTAACTTGGCCAACTTATGACGAAAGCAAACTGGTCG
AAGCAGAGGTCGAAATCGTAGTTCAAATCAAGGGTAAAGTTCGTGCTAAGCTAGTCGTAGCTAAGGACTTGAGCCGTGAG
GAACTGCAGGAAATCGCTCTGTCAGATGAAAAAATCAAGTCCGAAATCGCTGGCAAAGAAATCGTCAAAGTGATTAGTGT
TCCAAATAAACTGGTTAATATTGTGGTGAAATAA

Protein sequence :
MEKRMAYYNHKEIEPKWQKYWAEHHTFKTGTDKDKPNFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRTQGYNVLHP
MGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYDWDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPV
NWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLEELDWPESIKDMQRNWIGKSTGANVTFKI
KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITSAEQAQAVADYKHAASLKSDLARTDLAKDKTGVWTGAYAINPVN
GKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIPVLEGGNVAEAAYTEDGPHINSGFLDGLDKAAAIDKM
VAWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTKDIRPSGTGESPLANLTDWLEV
TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNNEKLADEELLKAWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVP
TKEPFQKLFNQGMILGTSYRDSRCALVATDKVEKRDGSFFNIETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY
EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLFNSKELVTENSGALDKVYHETVKSVTEQIEELKFNTAIAQLMIFVNAAN
KEEKLYVEYAKGFIQLLAPFAPHLAEELWQAVAQTGESISYVTWPTYDESKLVEAEVEIVVQIKGKVRAKLVVAKDLSRE
ELQEIALSDEKIKSEIAGKEIVKVISVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 90