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Name : tpx (SSA_0259) Accession : YP_001034268.1 Strain : Streptococcus sanguinis SK36 Genome accession: NC_009009 Putative virulence/resistance : Virulence Product : thiol peroxidase Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG2077 EC number : 1.11.1.- Position : 253103 - 253633 bp Length : 531 bp Strand : - Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein DNA sequence : ATGTACAATGAAGCTATCAAACATGAATGGAGACTTCCTATGACAACTTTTCTCGGAAATCCTGTAACCTTTACTGGAAA GCAACTGCAAGTCGGCGACACCGCCCACGATTTTAGCCTGACAGCAACTGACCTTTCAAAGAAAACTCTGGCTGACTTTG CTGGCAAAAAGAAAGTCCTGAGCATCATCCCATCTATCGATACTGGTGTCTGTTCGACTCAGACTCGTCGTTTCAATCAA GAACTCTCTGACTTGGACAATACCGTTGTTATCACGGTTTCAGTTGATTTGCCTTTTGCTCAAGGCAAGTGGTGTGCTGC TGAAGGCATTGAGAATGCTGTCATGCTCTCTGACTACTTCGACCATTCTTTCGGCCGTGACTATGCTGTCCTCATCAATG AATGGCACCTTTTGGCCCGTGCGGTTCTTGTCTTAGACGAAAACAACACTGTGACCTACGCTGAATATGTCGACAATATC AATACCGAGCCTGACTATGATGCGGCGATTGCAGCAGTTAAGAGTTTATAA Protein sequence : MYNEAIKHEWRLPMTTFLGNPVTFTGKQLQVGDTAHDFSLTATDLSKKTLADFAGKKKVLSIIPSIDTGVCSTQTRRFNQ ELSDLDNTVVITVSVDLPFAQGKWCAAEGIENAVMLSDYFDHSFGRDYAVLINEWHLLARAVLVLDENNTVTYAEYVDNI NTEPDYDAAIAAVKSL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tpx | YP_001216305.1 | thiol peroxidase | Not tested | VPI-1 | Protein | 5e-22 | 42 |
| tpx | NP_230472.1 | thiol peroxidase | Virulence | VPI-1 | Protein | 2e-22 | 42 |
| tagD | AAK20751.1 | toxR-activated gene D protein | Virulence | VPI | Protein | 3e-22 | 42 |
| tagD | AAK20781.1 | toxR-activated gene D protein | Virulence | VPI | Protein | 2e-22 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| tpx | YP_001034268.1 | thiol peroxidase | VFG0087 | Protein | 6e-23 | 42 |
