Gene Information

Name : nisR (SSA_0204)
Accession : YP_001034214.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Resistance
Product : nisin biosynthesis two-component response transcriptional regulator nisR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 202197 - 202895 bp
Length : 699 bp
Strand : +
Note : GC: 44.35%; Codon Adaptation Index (CAI): 0.765. Curator(s): P. Manque , J. Alves

DNA sequence :
ATGGAAATTATGAGACAGTATCGTATTTTGGTGGTTGATGACGACCGGAGCATTTTGAAGCTGGTGAAAAATGTCCTAGA
GCTCGATGCTTATGATGTGACGACGCTTGATCGGATAGAAGAGCTAGAGCTGACGAATTTTGTCGGATATGACTTGATTC
TGCTGGATGTGATGATGGAGCCTGTTAATGGTTTTGAGCTGTGTTCCTACATTCGTCCCCATATTTCGTGTCCAATCATC
TTTCTGACGGCCAAGGAATTGGAGGCGGACAAGGTGGAAGGGCTCTTTCGTGGAGCAGATGACTATATTGTCAAACCTTT
TGGGACCAAAGAATTGCTGGCGCGTGTCAGAGCTCATCTTCGGCGGGAGGAAAGACGTGAGGAGCGATATTCTGAAATTG
CTTCTTGTCAATTTTATCCAGAGCGCTATGAAGTTGCCTGTTTTGGTAAAGTCTTGAAATTTTCAGAGCGAGAGTTTAAG
TTGCTACATTTACTAGCTAGCAATCCCAAGCAGACCTTTTCAGCTGAACGCCTGCATACCTTGCTTTACCCAGAAAGCTC
AGAAACACAGCTTCGCTCCATCTCAGAATACGTATATCAGATTCGTCAAAAATGCAAACAAGAAGGGTTGCAAGCAATCG
CAACAGTGAGAGGAGTAGGCTATAGATGGCAATTAGAACCCGAAATTTCAAAAGCCTAG

Protein sequence :
MEIMRQYRILVVDDDRSILKLVKNVLELDAYDVTTLDRIEELELTNFVGYDLILLDVMMEPVNGFELCSYIRPHISCPII
FLTAKELEADKVEGLFRGADDYIVKPFGTKELLARVRAHLRREERREERYSEIASCQFYPERYEVACFGKVLKFSEREFK
LLHLLASNPKQTFSAERLHTLLYPESSETQLRSISEYVYQIRQKCKQEGLQAIATVRGVGYRWQLEPEISKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nisR2 YP_006309922.1 NisR Not tested FWisland_1 Protein 4e-38 51
SSU05_0907 YP_001198273.1 NisR Not tested 89K Protein 7e-35 46
nisR YP_006309898.1 NisR Not tested FWisland_1 Protein 8e-36 44