Gene Information

Name : tkt (SSA_2075)
Accession : YP_001035996.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2077203 - 2079179 bp
Length : 1977 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCACAATTATCAGTTAATGCCATTCGCTTTTTAGGGATTGACGCGATTGAAAAGTCTAAGTCAGGTCACCCTGGCGT
AGTCATGGGCGCTGCGCCGATGGCTTATGACTTGTTTACTAAACAACTTCGTATCAATCCAGAAGAGCCAAACTGGATTA
ACCGCGATCGCTTCGTCCTGTCTGCAGGACATGGTTCTATGCTGCTTTATGCCTTGCTTCATCTGTCTGGCTTTAAAGAT
GTCAGCATGGACGAAATCAAAAATTTCCGCCAATGGGGTTCTAAGACACCAGGTCACCCAGAGTTTGGTCACACAGCTGG
TGTTGATGCCACCACTGGCCCACTGGGACAGGGTATTTCTACAGCTACTGGATTTGCTCAGGCAGAGCGTTTCTTGGCTG
CTAAGTATAATCGTGAAGGCTACCCAATTTTCGACCATTACACTTATGTCATCTGTGGTGATGGTGATTTGATGGAGGGG
GTTTCAGCTGAAGCTGCTTCTTATGCTGGGCTGCAAAAGCTGGACAAGCTGGTTGTTCTCTATGATTCAAATGATATCAA
CCTAGATGGAGAGACCAAGGATTCCTTTACAGAAGATGTTCGTGCCCGCTATGAAGCATATGGTTGGCATACTGCCTTGG
TAGAAGATGGAACAGACCTTGCAGCGATTGATGCAGCCATCAATGAAGCTAAAGCTTCCGGCAAACCATCTTTGATTGAA
GTCAAGACGGTTATCGGTTACGGTTCTCCAAACAAGCAAGGAACGAATGCAGTGCACGGTGCGCCTCTGGGAGCAGAAGA
AGCGGCAGCTACTCGTAAAGCCTTGGGCTGGGACTATGCGCCATTTGAGATTCCTGAGGAAGTCTATGCAGATTACCGTA
CAAATGTGGCAGAGCGTGGTGCAGCGGCATACGATGCTTGGGAACAGCTGGTAGAGGACTACAAGCAAGCCCATCCAGAG
TTGGCAGAAGAAGTAGCAGCTATCATTGCTGGTCAAGATCCAGTAGAGATTAAGCCAGAAGACTTCCCAGTGCTTGAAAA
TGGCTTCTCTCAAGCGACCCGTAATTCTAGTCAGGATGCTCTCAATGCAGCAGCTAAGGTGCTTCCAACTTTCCTCGGCG
GTTCTGCTGACTTGGCTCATTCCAATATGACCTACATCAAGGAAGACGGTCTGCAGGATGATGCCCACCGTCTCAACCGC
AACATCCAATTTGGTGTGCGCGAGTTTGCCATGGGAACAATTCTTAACGGTATGGCGCTTCATGGTGGGCTTCGCGTTTA
CGGTGGAACCTTCTTCGTCTTTTCAGACTATGTTAAGGCAGCTGTTCGTTTGTCTGCTTTGCAAGGCTTGCCAGTGACTT
ATGTCTTCACACACGACTCTATTGCAGTTGGTGAAGACGGTCCGACACATGAGCCGATTGAGCATTTGGCTGGTCTGCGT
GCCATTCCAAACCTGACTGTTTTCCGCCCAGCAGATGCGCGTGAAACTCAGGCAGCTTGGTACCTGGCCCTTAAGAGTCA
ATCCACTCCGACTGCTCTGATCTTGACCCGTCAAAATCTGACAGTCGAAGAAGGAACAAACTTTGACAAGGTAGCTAAAG
GCGCTTATGTCGTTTACGAAACAGGAGCAGATTTTGATACCATCTTGCTGGCTTCTGGTTCTGAGGTTAATTTGGCAGTT
GCAGCTGCTAAAGCACTTGCAGCAGAAGGCGCTAAAATCCGCGTTGTCAGCGTGCCATCAACAGAGCTTTTTGATGCTCA
AGATGCAGCCTACAAAGAAGAAATTCTGCCAAATGCAGTTCGTCGCCGCGTAGCGATCGAGATGGCAGCCAGCCAGCCTT
GGTACAAGTATGTCGGTCTGGACGGTGCAGTTATCGGAATCGACCAGTTCGGTGCATCTGCTCCAGCAGGCAAGGTTCTG
GAAGAATATGGCTTTACAGTTGAGCATGTAGCAGAAGTTGTTAAAAATCTTAAATAA

Protein sequence :
MSQLSVNAIRFLGIDAIEKSKSGHPGVVMGAAPMAYDLFTKQLRINPEEPNWINRDRFVLSAGHGSMLLYALLHLSGFKD
VSMDEIKNFRQWGSKTPGHPEFGHTAGVDATTGPLGQGISTATGFAQAERFLAAKYNREGYPIFDHYTYVICGDGDLMEG
VSAEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTEDVRARYEAYGWHTALVEDGTDLAAIDAAINEAKASGKPSLIE
VKTVIGYGSPNKQGTNAVHGAPLGAEEAAATRKALGWDYAPFEIPEEVYADYRTNVAERGAAAYDAWEQLVEDYKQAHPE
LAEEVAAIIAGQDPVEIKPEDFPVLENGFSQATRNSSQDALNAAAKVLPTFLGGSADLAHSNMTYIKEDGLQDDAHRLNR
NIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGLPVTYVFTHDSIAVGEDGPTHEPIEHLAGLR
AIPNLTVFRPADARETQAAWYLALKSQSTPTALILTRQNLTVEEGTNFDKVAKGAYVVYETGADFDTILLASGSEVNLAV
AAAKALAAEGAKIRVVSVPSTELFDAQDAAYKEEILPNAVRRRVAIEMAASQPWYKYVGLDGAVIGIDQFGASAPAGKVL
EEYGFTVEHVAEVVKNLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-145 51
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-137 48