Gene Information

Name : SSA_1741 (SSA_1741)
Accession : YP_001035673.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Virulence
Product : Fe3+-siderophores ABC transporter ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : 3.6.3.34
Position : 1728147 - 1728932 bp
Length : 786 bp
Strand : +
Note : GC: 48.73%; Transporter classification TC:3.A.1.14.7. Codon Adaptation Index (CAI): 0.783. Curator(s): J. Alves

DNA sequence : 
ATGTCCACTATCTCTGCAGCAAGTATCCAGGTCGCCTACGATCAAAAGGTTATTATTGACGGACTGGACTGCCAACTAGC
CGAGGGAAAGATTACAACTATTATCGGTAGCAATGGCTGCGGTAAATCGACTCTTCTCAAGGCTTTTACCCGTATTTTAC
CGACAAAAGCCGGCAGCATAACCCTGGATGGACAGTCCATCGCCCTACTGCCGACCAAGGAGGTGGCGCAAAAGATTGCC
TTGCTGCCCCAAACCATGGAGGCGACCGATGGCATCACCGTCTATGATCTGGTCTCTTATGGCCGCTTTCCGCATCAAAC
TGGCTTGGGCCGGCTCAGTACAGAAGACCGGGAAAAAATCTGCTGGGCTATGGAAGCAACTCAGGTCAGCGAATTTTCGG
ACTGGCAGGTGGATGATTTGTCTGGTGGTCAGCGCCAGCGTGTCTGGATTGCTATGGCCTTAGCTCAAGATACAGAGACT
ATTTTTCTGGACGAGCCGACCACCTATCTGGATATGAATCACCAGCTGGAAATCTTGGAGTTGCTGAATGACCTCAACCG
ACTCAGCGGAAAAACCATTATCATGGTTCTGCATGACATCAACTTAGCTGCCCGCTTTTCCCATCAGCTGATCGCTATGA
AAAATGGGCATATCCGATATCAAGGAAGTGTTGAGCAGGTCATGACTTCGGATATTCTGAGAGACATTTTTCAGATTGAA
GCCCAAATTATTCGAGATCCTATTCAGGATAAGCCGCTCTGCCTCAGCTATCAGCTCGTTAAATAA

Protein sequence : 
MSTISAASIQVAYDQKVIIDGLDCQLAEGKITTIIGSNGCGKSTLLKAFTRILPTKAGSITLDGQSIALLPTKEVAQKIA
LLPQTMEATDGITVYDLVSYGRFPHQTGLGRLSTEDREKICWAMEATQVSEFSDWQVDDLSGGQRQRVWIAMALAQDTET
IFLDEPTTYLDMNHQLEILELLNDLNRLSGKTIIMVLHDINLAARFSHQLIAMKNGHIRYQGSVEQVMTSDILRDIFQIE
AQIIRDPIQDKPLCLSYQLVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 5e-54 48
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 5e-54 48
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-56 47
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 9e-57 45
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 1e-48 44
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 1e-48 44
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 1e-48 44
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 1e-48 44
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-49 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSA_1741 YP_001035673.1 Fe3+-siderophores ABC transporter ATPase BAC0164 Protein 6e-57 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSA_1741 YP_001035673.1 Fe3+-siderophores ABC transporter ATPase VFG1042 Protein 5e-57 45
SSA_1741 YP_001035673.1 Fe3+-siderophores ABC transporter ATPase VFG0925 Protein 1e-49 42