Gene Information

Name : polA (SSA_0100)
Accession : YP_001034111.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 100820 - 103462 bp
Length : 2643 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAAAAAAGAACAAGTTATTATTAATCGATGGTTCGTCCGTTGCTTTTCGCGCTTTTTTTGCGCTTTATAATCAAAT
CGACCGTTTCAAGAGTCCATCGGGCCTGCATACCAATGCCATTTATGGCTTCCACCTCATGCTCAATCATCTCTTGGAGC
GCGTGCAGCCGACTCATGTCCTGGTAGCTTTTGATGCTGGCAAGACGACCTTCCGGACCGAGATGTACGCCGACTATAAG
GCAGGGCGGGCCAAGACACCGGATGAATTTCGTGAGCAGCTGCCCTTTATCCGAGAAATGCTGAAGCACCTAGGCATTCA
CTACTACGACTTGGCTCAGTACGAGGCGGATGACATCATCGGAACCTTGGACAAGATGGCTGAAAAGACAGCTGTGCCTT
ACGATGTGACCATTGTCAGCGGCGATAAAGACTTGATTCAGCTGACGGATGAAAATACCGTGGTGGAGATTTCCAAGAAA
GGCGTAGCTGAGTTTGAGGAATTTACCCCAGCCTACCTCATGGAAAAGATGGGCATCACGCCAGAGCAGTTCATTGACCT
CAAGGCGCTGATGGGCGATCAGTCGGATAATATCCCCGGCGTGACCAAGATTGGTGAGAAGACTGGCCTCAAGCTCCTCT
TGGAGTATGGCTCTTTGGAAAATCTCTATGAAAATATTGATCAGCTCAAGGCTTCCAAGATGAAGGAAAATCTGATCAAT
GACAAGGACAAGGCTTTCTTATCAAAAACCCTAGCCACCATCAATACTCAGGCTCCGATTGAAATCGGGCTGGATGATTT
GGTTTATAAGGGTCCGCAGGTAGAGGCTCTGAGCAAGTTCTATGACGAGATGGGCTTCAAGCAGCTCAAGGCTCAGCTGG
GAACTGGTCAAGATCCGGTAGAAGTCAAACCAATTGAATTTACCAAAGTGACTGAGGTGACAGCAGATATGCTGGCACCA
GAGCAGTTCTTCTATTTTGAAATCTTGGGTGACAACTACCACAAGGAAGAGGTTGTCGGTCTTGCCTGGGGCGATAGCCG
TCAGATTTATGTCGGCTCTAGCGACTTACTGCAGCAGCCTCTCTTTCAGGAATTTTTGACAAAAACAGCTCTGAAAACTT
ACGATATCAAGCGGGCCAAGGTATTGCTCAGTCATTACGGCATTGAACTGCCGGCAGCAGCCTTTGATGCGCGCCTAGCC
AAGTATCTGCTTTCGACAGTCGAGGATAATGAGCTGGTGACTATTGCTCGCCTCTACGGCCAAACAATTCTGCCGACGGA
TGACGAGGTTTATGGCAAGGGAGCCAAGCGCGCTTTGCCGGAGCAAGAGCAGCTCTTTAAGCATCTAGCTCGTAAGATCC
AAGTACTGCTGGAAACAGAAGAACCTATGCAAGAACAGCTTCGCGCCCACGATCAGCTGGATTTGTTGCTTGAAATGGAG
CAGCCGCTGGCCTTTGTCCTAGCCAAGATGGAGATTGCGGGGATCAAGGTTGAGCGGGAAACCCTGCAGGGCATGCAGGC
GGAAAATGAAAAGACGCTGGAAAGTCTGACTCAGGAGATTTATGATCTGGCTGGTCAGGAGTTCAATATTAACTCGCCGA
AACAGCTGGGAACCATTCTCTTTGAGGATATGGGGTTGCCACTGGAGTACACCAAAAAGACCAAGACGGGCTACTCGACA
GCAGTCGATGTGCTGGAGCGTCTAGCTCCCATTGCACCGATTGTGTCTAAGATTCTGGAATACCGTCAAATCAGCAAGCT
CCAGTCCACTTATATCATCGGCCTGCAGGAGGCGATAGCGGCTGACGGTAAGATTCACACTCGCTATGTTCAGGATTTGA
CTCAGACTGGCCGCCTGTCCTCGGTTGACCCAAACCTGCAGAATATCCCCGTTCGTTTGGAGCAGGGGCGCCTCATTCGC
AAGGCCTTTGTGCCAGAGTGGGCAGACAGTGTGCTTCTCAGTTCGGATTATTCCCAGATTGAGCTGCGGGTGCTGGCTCA
TATTTCGCAGGACGAGCATCTGATTGCTGCCTTTCAGCATGGAGAAGATATTCACACGGCTACAGCCATGCGGGTCTTTG
GTATTGAAAAGGCAGAGGATGTGACGCCTAATGACCGCCGCAATGCCAAGGCTGTCAACTTCGGAGTAGTCTATGGCATT
TCCGACTTCGGACTGGCCAATAATTTGGGAATTTCCCGCAAGGCTGCCAAAGATTATATTCAGACTTATTTTGAGCGTTT
CCCAGGAATCAAAAATTATATGGAAACCATTGTTCGCGAAGCGCGTGATAAGGGATATGTAGAGACCATTTACCATCGCC
GTCGCTCCTTGCCGGACATCAATTCCCGCAACTTTAACATCCGAAATTTTGCGGAGCGCACAGCCATTAACAGCCCCATC
CAAGGCTCCGCCGCAGATATTCTCAAAGTTGCTATGATTAATCTGGATCGAGCTCTAACAGAGAAGAATTTCAAGTCTCG
CATGCTCTTGCAGGTTCACGATGAAATCGTGCTGGAAGTGCCAAATGACGAGCTAACAGCCGTTCGCAAGCTGGTCAAAG
AAACCATGGAAACTGCGATTGAGCTGGCCGTTCCACTAGTGGCTGATGAAAATGCCGGCCAAACTTGGTACGAGGCAAAG
TAA

Protein sequence :
MEKKNKLLLIDGSSVAFRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLLERVQPTHVLVAFDAGKTTFRTEMYADYK
AGRAKTPDEFREQLPFIREMLKHLGIHYYDLAQYEADDIIGTLDKMAEKTAVPYDVTIVSGDKDLIQLTDENTVVEISKK
GVAEFEEFTPAYLMEKMGITPEQFIDLKALMGDQSDNIPGVTKIGEKTGLKLLLEYGSLENLYENIDQLKASKMKENLIN
DKDKAFLSKTLATINTQAPIEIGLDDLVYKGPQVEALSKFYDEMGFKQLKAQLGTGQDPVEVKPIEFTKVTEVTADMLAP
EQFFYFEILGDNYHKEEVVGLAWGDSRQIYVGSSDLLQQPLFQEFLTKTALKTYDIKRAKVLLSHYGIELPAAAFDARLA
KYLLSTVEDNELVTIARLYGQTILPTDDEVYGKGAKRALPEQEQLFKHLARKIQVLLETEEPMQEQLRAHDQLDLLLEME
QPLAFVLAKMEIAGIKVERETLQGMQAENEKTLESLTQEIYDLAGQEFNINSPKQLGTILFEDMGLPLEYTKKTKTGYST
AVDVLERLAPIAPIVSKILEYRQISKLQSTYIIGLQEAIAADGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIR
KAFVPEWADSVLLSSDYSQIELRVLAHISQDEHLIAAFQHGEDIHTATAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGI
SDFGLANNLGISRKAAKDYIQTYFERFPGIKNYMETIVREARDKGYVETIYHRRRSLPDINSRNFNIRNFAERTAINSPI
QGSAADILKVAMINLDRALTEKNFKSRMLLQVHDEIVLEVPNDELTAVRKLVKETMETAIELAVPLVADENAGQTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 76