Gene Information

Name : tkt (llmg_0868)
Accession : YP_001032195.1
Strain : Lactococcus lactis MG1363
Genome accession: NC_009004
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 837369 - 839345 bp
Length : 1977 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTTTGATACTACTGATCAATTGGCTGTAAATACGATTCGTACTCTATCATTAGATGCGATTCAAAAAGCAAATTCAGG
ACATCCTGGACTTCCAATGGGCTCTGCCCCAATGGCTTATGTACTTTGGAGCAAGTTTCTTAATGTAAACCCAAAAACGA
GTCGTAAATGGTCAAATCGTGACCGTTTTGTCTTGTCGGCTGGTCATGGTTCTGCAATGTTATATAGTTTGTTACACTTG
GCAGGATATAATGTAACGACTGATGATTTAAAAGGTTTCCGTCAATGGCAATCAAAAACACCAGGACATCCAGAAGTTAA
CCATACAGATGGTGTCGAAGCAACAACAGGTCCTTTGGGACAAGGAATTGCCAATGCTGTTGGAATGGCAATGGCTGAGG
CACATTTAGCTGCACAATATAATAAACCTGGTTTTGATATTGTTGACCATTATACTTATGCCTTAAATGGTGATGGTGAT
TTAATGGAAGGTGTTTCACAAGAAGCTGCTTCACTTGCAGGTAAATTGAAACTTGGTAAATTGATTCTTTTCTATGATTC
AAATAATATCTCTCTTGATGGTGATTTATCTATGTCATTTATTGATGATATTCAAAAACGTTTTGAATCATATGGTTGGC
AACATTTATTGGTAAAAGATGGTAATGATTTGGAAGAAATTGCTGCTGCTGTCGAAGTGGCTAAAGCTGAAAAATCTAAA
CCAACAATTATTGAAGTTAAAACAGTCATTGGTTTTGGTGCTGAAAAACAAGGAACTTCAGCAGTTCATGGAGCCCCTCT
TGGAGCTGACGGTGTAGCTTTTGCTAAGAAAGCTTATGGTTGGGATTATCCAGAATTTACTGTTCCTGAAGAAGTTTCAA
AACGCTTTTTAGAAACGACAGTTGCGCGTGGTGAAGCGATGGAGCAAGTATGGCGTGGCACTTTTGATGATTATTCTGAA
AAATACCCTGAGCTTGCTGAACAATATGTAAAAGCTTTTGAAAATGAAACACCAGAGCTTACATTGACCAAACATGAAAT
GGAAACAAGTAAGGCAAGTCGTGTGACTTCCCAAGAAGCTATTCAAGAACTATCTGCTCAAATGCCAAATCTCTGGGGAG
GGTCTGCTGACCTTTCAGCTTCAAATAATACAATGGTTAAAGTTGAAGAAGACTTCATGCCAGATAACTATGTTGGACGT
AATATTTGGTTCGGTGTTCGTGAATTCGCAATGGGTGCCATTATGAACGGAATTGCTTTGCATGGTGGAACTCGTGTTTA
TGGTGGAACATTCTTTGTCTTCTCAAACTATATGCTTCCTTCTGTTCGGATGGCTGCTCTACAAAGCTTGCCAGTTACTT
ATGTCTGGACACATGATTCGATTGCTGTCGGTGAAGATGGACCAACTCATGAACCTGTCGAACAACTGGCTTCTGTTCGT
TCAATTCCGAATTTGGATGTGATTCGTCCAGCTGATGGAAATGAAGTAGTGGCTGCATGGCGTCGTGCTGCTTCAAGTAA
AAGCCGTCCAACCGCACTTATTTTGACTCGTCAAAATCTTCCAGTTTTACCTGATACTTATGAATTGGCTGAAGAAGGTT
TAAATCGTGGGGCTTATATTCTTTCTAAAGAAGAAGGTAAACTTGAAGGAATTATCATTGCGACTGGTTCAGAAGTAGCT
TTGGCACTTGAAGCGAAGAAGACTTTAGGTTCTGGTATTCGTGTTGTTTCAATGCCTTCAATGAATATCTTTGATGAGCA
GTCAGCAGACTATCGCGAAGAAATTTTACCTAAATCAGTTAGACGTCGTTTAGCGATTGAAGCTGGAACAAGTTACGGTT
GGGGTAAATATGTTGGACTTGATGGTGCAACAGTTACAGTAGACACTTGGGGCGCTTCGGCACCAGCAAATATCGTTCTT
CCGGCTTACGGATTTACCGCTGAAAATGTAATTAAAGTATATCAATCTTTAGATTGA

Protein sequence :
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGADGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRGTFDDYSE
KYPELAEQYVKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYVGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQSADYREEILPKSVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVIKVYQSLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-127 51
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 6e-129 49