Gene Information

Name : polA (llmg_2425)
Accession : YP_001033666.1
Strain : Lactococcus lactis MG1363
Genome accession: NC_009004
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2367757 - 2370390 bp
Length : 2634 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAGATAAGAATAGACTTTTGCTAATTGATGGGTCATCGGTTGCTTTTCGAGCGTTTTTCGCATTATATAATCAGTT
AGATCGGTTCAAAGCACCTAATGGCTTACATACAAATGCCATTTTTGCTTTTCATACGATGTTATCTTCTTTGATGGAAC
GAATTCAACCGACACATGTGTTGATTGCTTTTGATGCGGGGAAAACCACTTTTCGGACGGAAATGTTTGCGGATTATAAA
GGGGGACGGTCAAAAACACCCGATGAGTTTCGCGAGCAATTGCCTTTTATTAAGGAAATGATTGAGAAGTTAGGAATTCG
ACACTATGAGTTGGCAAACTATGAGGCTGATGATATTATCGGAACTTTGGATAAAATGGCTGAAGCGCCTGATGTGAATT
TCGATGTGACCATTGTGACCGGGGACAAGGATATGATTCAGCTGGTCGATGGAAATACACGAGTGGAAATTTCTAAAAAG
GGTGTGGCTGAGTTTGAGGAATTTACACCTGACTATCTCTTAGAAAAAATGGGACTTACGCCATCACAATTTATTGATTT
GAAGGCTTTGATGGGCGATTCTTCGGATAATTATCCTGGCGTCACTAAAGTTGGTGAAAAAACGGGTCTTAAACTTTTAC
AGGAATTTGGTTCACTGGAAAATCTTTATGAAAATGTTGAGACGCTAAAAGCCAGCAAGATGAAGGATAATCTAATTGCT
GACAAGGAAATGGCCTTTTTGTCACAGCAATTGGCGACAATCAATACGAAAGCTCCTCTTGAAATTGGTTTAGAAGATAC
GCTTTTAAAAGAAAAAAATGTGGCTGAACTGGGTCAATTTTATGATGAAATGGGATTTTCACAATTCAAAAGTAAGTTAT
TAGCTGACGGCGGTGGAGAAGTTACTGACGAAACTGTCAGTGAAGAAATTAAGTTTGAAATAGTTACTGACAAAAGTTCA
GTTGCTTCAGTCAATGCTGATGATTTCTTTTATTTGGAAACTTTGGGTGAAAATTATCATCGTGAGCAGATTGTGGCATT
TGCTTGGGGAAATTCTGAGAAAATTTATGTTTCAAAAAATCTAGATTTACTGACAGAAATGAAATTTCCTGAAAATACTT
ATGATTTCAAGAAAAATCGCGTACTTTTGAGCCACTTAAATATTGAATTGCCTCTGGTTAAATTTGATGCTATGCTTGCA
AAATATTTGATTTCTACAACGGAAGATAATAAAATTTCAACCATTGCACGACTTTTTGATGTGGGACATTTGGCCACTGA
TGAGGAAATTTTTGGCAAAGGTACAAAACTTGCTCTACCTGATGATGAGATTTTGTTTGACCATTTGGCTCGTAAAATCA
GAGTTTTAGCTCGTGCCAAAGAAAAAATGATGGCCGAACTTATTGAAAATGAACAAGAACATCTTTTGTCTGATATGGAA
TTACCATTAGCAGAAGTTTTGGCAAAAATGGAGATTACAGGAATTTCTGTTAGTCAAAATACCTTGGAAGAAATTGGCGC
AGAAAACGAAGAAAAATTGGCTTCGTTGACTCGTGAAATTTATGATTTGGCTGGTGAAGAATTTAATATTAATTCGCCAA
AACAGTTGGGTGTGATTTTATTTGAAAAATTACAATTGCCAGTAGGTAAGAAAACAAAAACGGGTTATTCAACGGCGGTG
GATGTTTTAGAAGACTTGGCTGCATTATCTCCTGTGGTGGCAAAGATTTTGGAATATCGTCAAATCAATAAAGTACAATC
GACTTATGTTAAAGGCTTGATTCCGCAAATTGCTGATGATGGAAAAATCCATACGCGATATGTTCAGGACTTGACTCAGA
CCGGTCGTTTGAGTTCGGTTGACCCGAATCTGCAAAATATTCCTGTTCGACTGGAAGAAGGACGGAAGATTCGTAAGGCA
TTTGTGCCAAGTCAAGATTCTCTTTTGTTGAGTTCCGACTATTCACAAATTGAATTGCGAGTGCTGGCTCATATTTCTGC
TGATGAGCATTTGATTGACGCCTTTAAACATGGGGCTGATATCCATACGTCAACGGCTATGCGGGTCTTTGGCATTGAAA
AAGCAGAAGATGTCACGGCAAATGACCGCCGAAACGCAAAAGCAGTCAATTTTGGTGTGGTTTATGGAATTTCGGATTTT
GGTTTGGCAAGAAATCTGGGAATTACAAGAAAAGATGCCAAAAATTATATTGAAACTTACTTTGAACGTTATCCTGGTAT
TAAAACTTATATGGAAAATATTGTTCGCGAGGCTAGAGATAAAGGATTTGTTGAGACAATGAGTCATCGTCGTCGTAAGA
TTCCAGATATTAATGCACGTAATTTTAATGTTCGTGGTTTTGCGGAGCGGACGGCAATTAATTCGCCAATCCAAGGATCG
GCAGCGGATATTTTGAAAATTGCGATGATTAATCTGGATAAAGCGCTGACGGAACGTCAATCAAAATCAAAATTATTATT
GCAAGTACACGATGAAATTATTCTAGATGTTCCACTCGAGGAATTGGAGGATATCAAGGCACTTGTAAAGCAAACAATGG
AAGAAGCAATTGAACTTGCTGTGCCATTGAAAGTGGATGATAATACTGGTAAAACTTGGTATGAAGCCAAATAA

Protein sequence :
MEDKNRLLLIDGSSVAFRAFFALYNQLDRFKAPNGLHTNAIFAFHTMLSSLMERIQPTHVLIAFDAGKTTFRTEMFADYK
GGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDIIGTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKK
GVAEFEEFTPDYLLEKMGLTPSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKASKMKDNLIA
DKEMAFLSQQLATINTKAPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKSKLLADGGGEVTDETVSEEIKFEIVTDKSS
VASVNADDFFYLETLGENYHREQIVAFAWGNSEKIYVSKNLDLLTEMKFPENTYDFKKNRVLLSHLNIELPLVKFDAMLA
KYLISTTEDNKISTIARLFDVGHLATDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMAELIENEQEHLLSDME
LPLAEVLAKMEITGISVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPKQLGVILFEKLQLPVGKKTKTGYSTAV
DVLEDLAALSPVVAKILEYRQINKVQSTYVKGLIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKA
FVPSQDSLLLSSDYSQIELRVLAHISADEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNFGVVYGISDF
GLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRRRKIPDINARNFNVRGFAERTAINSPIQGS
AADILKIAMINLDKALTERQSKSKLLLQVHDEIILDVPLEELEDIKALVKQTMEEAIELAVPLKVDDNTGKTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 68