Gene Information

Name : leuS (llmg_1741)
Accession : YP_001033014.1
Strain : Lactococcus lactis MG1363
Genome accession: NC_009004
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1721185 - 1723674 bp
Length : 2490 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGAATACAATCATCAAAAAATAGAAGCCAAATGGCAAAAATACTGGGCGGATAACAAAACTTTCCGTACAGGAACAGA
TAAAAATAAACCAAAATTTTATGCTCTAGACATGTTCCCTTATCCATCTGGTGCAGGACTTCACGTTGGACACCCCGAAG
GTTATACTGCAACTGATATTTTGAGCCGTTACAAACGCGCTCAAGGGTTCAATGTTCTTCATCCAATGGGCTGGGATGCC
TTTGGTTTACCTGCTGAACAATATGCAATGGATACAGGAAATGACCCAGCAGAATTTACAGCTGAAAATATTGCTAACTT
TAAACGTCAAATCAATAGCTTAGGTTTTAGTTATGACTGGGAACGTGAAGTTAATACAACTGACCCAAATTTTTATAAAT
GGACACAGTGGATTTTTACTAAACTTTATGAAAAAGGGTTAGCTTATGAAGCAGAAGTAGCTGTTAACTGGGTTGAAGAA
CTCGGAACGGCTATTGCTAATGAAGAAGTGCTTCCAGACGGAACTTCTGAACGCGGGGGTTATCCTGTTGTTCGTAAACC
AATGCGCCAATGGATGCTTAAAATTACAGCTTATGCGGAACGTTTACTTGAAGACCTTGAAGAAGTTGATTGGCCTGAAT
CAATCAAAGAAATGCAACGGAATTGGATAGGGAAATCAGTAGGAGCAGATGTGACTTTTGAAGTTGCAGGAACCGACAAA
TCATTTGAAGTCTTTACGACTCGTCCTGATACCCTTTTTGGGGCAACTTATGCTGTGCTTGCACCTGAACATGATTTAGT
TGATGCTATTACGACACCTGAGCAAAAAGAAGCTGTTGCTGAATACCGTCGCAAAGCGAGCTTGAAATCTGATTTAGCCC
GTACAGACCTTTCTAAAGAAAAAACTGGAGCATTTACCGGAGCTTACGCGATTAACCCAATTAATGGCCGTAAAATGCCA
ATTTGGGTTGCAGATTATGTTCTTGCTTCTTATGGACATGGTGCTGTTATGGCAGTTCCTGCTCACGACGAACGTGACTG
GGAATTTGCTAAGGTCTATGGACTTGAAATTTTGCCTGTTGTTGAAGGTGGAAATGTAGAAGAAGCTGTTTATACAGAAG
ATGGCCCTCATATTAATTCAGAATTTTTGAATGGACTTGACAAAGCACAAGCGATTGAAAAAGCCATTGAATTTTTAGAA
GAAAAGAAAATTGGGAAAAAGAAAATCACTTACCGCTTGCGTGACTGGCTCTTTAGTCGTCAACGTTATTGGGGTGAACC
AATTCCAATTATTCATTGGGAAGATGGCACATCAACAGCGCTCTCAGAAGATGAACTTCCTCTTGTTTTACCAGTAACCT
CTGATATCAAACCGTCAGGAACTGGTGAGTCTCCTTTGGCTAACTTAACAGATTGGTTGGAAGTCACACGCGCAGATGGC
CTAAAAGGTCGCCGTGAAACTAATACAATGCCACAATGGGCAGGTTCAAGTTGGTATTACCTTCGCTATATTGACCCAAA
TAATAGCGAAGCTTTGGCAGACCCAGAACTTCTCAAAGAATGGTTGCCAGTTGATATCTATGTGGGAGGGGCTGAACATG
CTGTTCTTCACTTACTTTACGCTCGTTTCTGGCATAAAGTGCTTTATGATTTAGGAGTTGTTCCAACTAAAGAACCTTTC
CAAAAACTCTTTAACCAAGGAATGATTCTCGGAACCTCTTATCGTGATCATCGTGGGGCTTTGGTTGCAACTGATAAGGT
TGAAAAACGTGATGGTGGCTTTTACCATATGGAAACAGGTGAAGCCCTTGAACAAGCTCCAGCTAAAATGTCTAAATCTC
TTAAAAATGTTGTTAATCCTGATGATGTTGTTGAACATTATGGAGCTGATACTTTACGTGTTTATGAAATGTTCATGGGT
CCACTTGATGCAAGTATTCCATGGTCAGAAGAAGGCCTTGAAGGGGCTCGTAAATTCCTAGACCGAGCTGTTCGAATGAT
TGAAAATTCAGAGATTAAAGCTGAAAATAATGGAGAGTTGGACAAAGTTTACAATGAAACAGTGAAAAATGTTACTGAGC
GTTTGGACTTGATGTACTTTAACACTGCAATTTCCCAATTAATGATTTTTGTTAATGCAGTTAATAAAGCAAAAGCTTTA
CCGTTAGAATACGCTAATGGCTTTGTCCAACTTTTGGCGCCATTTGCACCACATATTGCTGAAGAACTTTGGGTAAAATT
AGGTAATGAAGCTGGAATTTCTTATGTTGCTTGGCCAACATTTGACGAAAGCAAATTAATTGAATCAGAAGTTGAAATTG
TTGTTCAAATTAATGGTAAATTAAAAGCAAAAATTAAAATTGCTAAAGATTTAGCGCGTGAAGAACTTGAAAAAATTGGT
CGTGAATCAGTTGCTGAGGCTCTTGAAGGTAAAAACGTGGTCAAAGTAATTGCTGTTCCAAATAAATTAGTTAATATTGT
TGTAAAATAA

Protein sequence :
MEYNHQKIEAKWQKYWADNKTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGFNVLHPMGWDA
FGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWEREVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEE
LGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFEVAGTDK
SFEVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQKEAVAEYRRKASLKSDLARTDLSKEKTGAFTGAYAINPINGRKMP
IWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVEGGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLE
EKKIGKKKITYRLRDWLFSRQRYWGEPIPIIHWEDGTSTALSEDELPLVLPVTSDIKPSGTGESPLANLTDWLEVTRADG
LKGRRETNTMPQWAGSSWYYLRYIDPNNSEALADPELLKEWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPF
QKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEALEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMG
PLDASIPWSEEGLEGARKFLDRAVRMIENSEIKAENNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNAVNKAKAL
PLEYANGFVQLLAPFAPHIAEELWVKLGNEAGISYVAWPTFDESKLIESEVEIVVQINGKLKAKIKIAKDLAREELEKIG
RESVAEALEGKNVVKVIAVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 82