Gene Information

Name : nrdE (llmg_1543)
Accession : YP_001032829.1
Strain : Lactococcus lactis MG1363
Genome accession: NC_009004
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1514411 - 1516579 bp
Length : 2169 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGTCTCTAAAACAACTTAAAGATGTAACTTATTTCAAGCTCAATAACGAGATTAACATCCCCGTGAATGGTAGCATTCC
TCTTGCCAAAGATAAAGAAGCAATTACCGCTTTTTTCAAAGAGAATGTTGAACCTAATCGTTATGAAGCTGACACTTATA
TCGATAAACTTAATTGGTTAGTTAAAGAAGAATACCTAGAAGCTGAATTTCTAGAAAAATATAAGCCAGAATTTATCACA
AATCTTCGTAAAGAATTGAGTAAATTTGAATTTCATTTTGATTCATTTATGGCTGCTTATAAATTTTATAATCAATATGC
CATGAAAAACAATGACGGTTCACTCTATCTTGAAGATTTTGAAGACCGTGTGTTAATGAATGCTTTATACATGGCTGACG
GTGATGAAAAATTAGCTAATAATCTTGCTTTTGCAATGATTAATCGTCGTTATCAACCGGCTACTCCAACTTTCTTAAAT
GCTGGACGTAAACGTCGTGGTGAATTCGTTTCTTGTTTTCTTTTACAATTGACTGATGATATGAATTCAATTGGGCGGAC
GATTAATTCTGCCTTACAACTTTCTAAAAATGGTGGTGGTGTTGGTCTTAATTTGACTAATCTGCGTGCTGCTGGTGCAC
CAATCAAAGGATATGATGGAGTTGCCGCTGGTGTTGTGCCTGTCATGAAACTTTTTGAAGATGCTTTTTCTTATGCCAAT
CAATTGGGGCAACGACAAGGTGCTGGTGTAGTTTATTTATCACTTTTCCATCCAGATATCATGGAATTTTTATCAACTAA
AAAAGAAAATGCTGACGAAAAAATCCGCGTTAAAACACTCTCACTTGGTGTTACTGTTCCTGATAAATTCTACGAATTGG
TTAAAAAAGGCGAAACAATGTATCTTTTTGAACCCTACTTCGTTGAAAAATACTATGGTAAACCTTTTGCCGAAGTCGAT
ATTACAGCTGAATACGACAAGATGGTGGCTAACCCAGAAATTCGCAAGACACCAATTAATGCCCGTGAGCTTGAACAAGA
ACTTTCAAAACTTCAACAAGAATCTGGTTATCCTTATATCGTGAATGTCGATACGGTCAATCAAGCTAATCCTGTTGATG
GGGTGATTTCAATGTCAAACCTTTGTTCTGAAATCCTTCAAGTTCAAACACCTTCTGTTTTGAATGATGACCAAACTTAT
AAAGTCGTTGGAACTGACGTTGCTTGTAACTTAGGTTCAACTAATGTCTTAAATATGATGACTTCCAGTGATGAATTTGG
AACTTCTGTTGAATCAATGGTTCGTGCTTTAACTTTCATTTCTGAAACTTCAAACCTGGATACTGTTCCAACTGTTCGTA
AAGGAAATGATGAAATGCATGCCATTGGGCTTGGAGCAATGGGCTTGCATTCTTTCTTAGCTCAAAATCAAATTCATTAT
GATAGTAAAGAAGCCGTTGAATTCACAAGTGTCTATTTCATGTTGTTGAATTACTACACTTTGGTGGCTTCAAATAAATT
AGCTGTTGAAAAAGGGTCTAGCTTCAAGAATTTTGAAAAATCGGCCTATGCTGATGGTTCTTATTTTGATAAATACTTGA
CTCATGATTATTTTGCAGCTGTTTCTCCTAAAGTTCAAGAACTTTTCAAAGGAATTGCCGTTCCAACAATCGCTGATTGG
ACTGAATTACGCGATACTGTAAAAACTTCTGGTCTTTATAATTCTTATCGTATGGCTGTAGCTCCAAATGGTTCTATTTC
TTATATCAATGACTGCTCTTCTTCTATCCACCCAATCGTCAATCGGATTGAAGAACGTCAAGAAAAGAAAGTTGGGAAAA
TTTATTATCCAGCTGCTGGACTTGCCACTGAAACAATTCCTTACTACAAATCCGCTTATGATACTGATATGCGCGCGGTC
ATTGATGTTTATGCGGCTGCTACAGAACACGTTGACCAAGGATTGTCACTCACATTATTTATGCGTTCAACTTTACCAGA
AGGTTTGTATGAATGGAAAGTTGCAAATAATAAAATGACCACACGTGATTTGTCTATTTTGCGTAACTATGCTTACAAAA
AAGGAATTAAAACAATTTATTACATTCGTACATTTACTGATGACCAAGAAGAAGTCGGCGCTAACCAATGTGAAAGTTGT
GTCATTTAA

Protein sequence :
MSLKQLKDVTYFKLNNEINIPVNGSIPLAKDKEAITAFFKENVEPNRYEADTYIDKLNWLVKEEYLEAEFLEKYKPEFIT
NLRKELSKFEFHFDSFMAAYKFYNQYAMKNNDGSLYLEDFEDRVLMNALYMADGDEKLANNLAFAMINRRYQPATPTFLN
AGRKRRGEFVSCFLLQLTDDMNSIGRTINSALQLSKNGGGVGLNLTNLRAAGAPIKGYDGVAAGVVPVMKLFEDAFSYAN
QLGQRQGAGVVYLSLFHPDIMEFLSTKKENADEKIRVKTLSLGVTVPDKFYELVKKGETMYLFEPYFVEKYYGKPFAEVD
ITAEYDKMVANPEIRKTPINARELEQELSKLQQESGYPYIVNVDTVNQANPVDGVISMSNLCSEILQVQTPSVLNDDQTY
KVVGTDVACNLGSTNVLNMMTSSDEFGTSVESMVRALTFISETSNLDTVPTVRKGNDEMHAIGLGAMGLHSFLAQNQIHY
DSKEAVEFTSVYFMLLNYYTLVASNKLAVEKGSSFKNFEKSAYADGSYFDKYLTHDYFAAVSPKVQELFKGIAVPTIADW
TELRDTVKTSGLYNSYRMAVAPNGSISYINDCSSSIHPIVNRIEERQEKKVGKIYYPAAGLATETIPYYKSAYDTDMRAV
IDVYAAATEHVDQGLSLTLFMRSTLPEGLYEWKVANNKMTTRDLSILRNYAYKKGIKTIYYIRTFTDDQEEVGANQCESC
VI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 1e-166 51