Gene Information

Name : panE (llmg_1131)
Accession : YP_001032445.1
Strain : Lactococcus lactis MG1363
Genome accession: NC_009004
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 1095546 - 1096484 bp
Length : 939 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAGAATCACAATTGCCGGTGCAGGAGCGATGGGAAGCCGTTTTGGGCTTATGCTTCATAGAGGGGGCAACGAAGTGAC
CCTTGTAGATGGTTGGCTTGAACATGTGACTGCAATTAAAGAACACGGCCTACAAGCAAATTTTAATGGTGAAGAAATCA
CTGCTCATCTATCAGTAGAATTACAATCTAATATTTCATCAGAAGAAAAAACAGATTTAATTATTTTATTTACGAAAGCA
ATGCAGTTAGATAAAATGCTTCAGGACATTAAACCTTTAATTGCTGAGCATACAAAAGTTCTTTGCTTACTTAATGGGAT
TGGTCATGAAGATATTATTGAAAAATATGTTTCTAAAAATAATATTTTTATTGGGAATACCATGTGGACTGCAGGTTTAG
AAGGACCAGGAAAAGCAAAACTATTTGGAAATGGTTCTGTTGAACTTCAAAATTTCATTCCTGGCGAAGAAGAAACGGCT
AAAAAATTAGCTGACATTTTATCTGCTTCAGGATTAAATGCTAACTATTCTGATAACATCCATTATTCAATTTACCGAAA
AGCGTGCGTTAATGGGACAATGAATGGACTCTGCACTATTTTGGATACTAATATGGCTGGATTGGGAGCAACAAAACCTG
CTCACGATATGGTTGTTACAATTGTCAAAGAATTTGCGGCAGTTGCAAAACATGAGGATGTGAATCTTGATATAGATGAG
GTCGTAGAACATGTTGAGACATGTTTTGACCCTGAAACTATTGGCTTACATTATCCTTCAATGTATCAAGATTTGATAAA
TAATAATCGCTTGACAGAGATAGATTATATTAATGGTGCAGTTTCACGTAAAGGGAAAAAATATCAGATAGCTACTCCTT
ACTGTGACTTTTTGACTCAATTAGTTCATAGTAAAGAAGAGTTATTAAAGGCGAAATAA

Protein sequence :
MRITIAGAGAMGSRFGLMLHRGGNEVTLVDGWLEHVTAIKEHGLQANFNGEEITAHLSVELQSNISSEEKTDLIILFTKA
MQLDKMLQDIKPLIAEHTKVLCLLNGIGHEDIIEKYVSKNNIFIGNTMWTAGLEGPGKAKLFGNGSVELQNFIPGEEETA
KKLADILSASGLNANYSDNIHYSIYRKACVNGTMNGLCTILDTNMAGLGATKPAHDMVVTIVKEFAAVAKHEDVNLDIDE
VVEHVETCFDPETIGLHYPSMYQDLINNNRLTEIDYINGAVSRKGKKYQIATPYCDFLTQLVHSKEELLKAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 9e-123 80
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 7e-123 80