Gene Information

Name : pyk (llmg_1119)
Accession : YP_001032433.1
Strain : Lactococcus lactis MG1363
Genome accession: NC_009004
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1079292 - 1080800 bp
Length : 1509 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAATAAACGTGTAAAAATCGTCTCAACTCTTGGACCTGCTGTCGAAATTCGTGGTGGCAAAAAATTTGGTGAAAGCGG
CTATTGGGGAGAATCTCTTGACGTCGAAGCATCAGCAAAAAACATTGCAGCTTTGATTGAAGAAGGCGCTAATGTCTTCC
GTTTCAACTTCTCACACGGTGACCATCCTGAACAAGGTGCTCGTATGGCAACTGTTCACCGCGCTGAAGAAATCGCTGGT
CACAAAGTAGGTTTCTTGCTTGATACTAAAGGTCCTGAAATGCGTACAGAACTCTTCACTGACGGTGCTGATTCAATCAG
CGTTGTTACTGGAGATAAATTCCGTGTTGCAACTAAACAAGGTCTTAAATCAACTCCTGAATTGATTGCCTTGAACGTAG
CTGGCGGACTTGACATCTTTGATGATGTTGAAATCGGTCAAACTATCTTGATTGATGATGGTAAACTTGGTTTGTCATTG
ACTGGTAAAGATGCAGCAACTCGTGAATTCGAAGTTGAAGCACAAAATGATGGTGTTATCGGTAAACAAAAAGGTGTTAA
CATTCCTAACACTAAAATTCCTTTCCCAGCCCTTGCTGAACGTGACGATGCAGATATCCGTTTCGGTCTTTCACAACCTG
GTGGAATTAACTTTATCGCTATCTCATTCGTACGTACTGCAAATGACGTTAAAGAAGTACGTCGTATTTGTGAAGAAACT
GGTAATCCACACGTACAACTTTTGGCTAAAATTGAAAACCAACAAGGGATTGAAAACCTTGATGAAATCATCGAAGCAGC
TGATGGTATCATGATTGCTCGTGGTGACATGGGTATCGAAGTTCCATTTGAAATGGTTCCAGTTTACCAAAAATTGATTA
TCAGCAAAGTTAACAAAGCAGGTAAAATTGTTGTAACTGCAACAAACATGCTTGAATCAATGACTTACAACCCACGTGCT
ACACGTTCAGAAATTTCAGACGTATTTAACGCTGTTATTGACGGAACTGATGCTACAATGCTTTCAGGTGAGTCTGCTAA
TGGTAAATACCCACGCGAATCAGTTCGTACAATGGCTACTGTTAACAAAAATGCTCAAACAATGTTGAAAGAATACGGAC
GTCTTCACCCAGAACGTTACGACAAATCAACTGTAACAGAAGTTGTTGCTGCATCAGTTAAAAATGCTGCAGAAGCTATG
GATGTTAAATTGATTGTTGCTTTGACTGAATCTGGTAACACAGCTCGTTTGATTTCTAAACACCGTCCAGATGCTGATAT
CTTGGCTATCACATTTGACGAAAAAGTTGAACGTGGATTGATGATCAACTGGGGTGTTATCCCAATGATGACTGAAAAAC
CTGCATCTACTGATGACATGTTTGAAGTTGCTGAAAAAGTTGCATTGGCTTCTGGTTTGGTTGAAGCTGGCGACAATATC
ATCATCGTTGCTGGTGTTCCAGTTGGTACTGGTCGCACTAATACAATGCGTATCCGCACTGTTAAATAA

Protein sequence :
MNKRVKIVSTLGPAVEIRGGKKFGESGYWGESLDVEASAKNIAALIEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAG
HKVGFLLDTKGPEMRTELFTDGADSISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQTILIDDGKLGLSL
TGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKEVRRICEET
GNPHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESMTYNPRA
TRSEISDVFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKNAQTMLKEYGRLHPERYDKSTVTEVVAASVKNAAEAM
DVKLIVALTESGNTARLISKHRPDADILAITFDEKVERGLMINWGVIPMMTEKPASTDDMFEVAEKVALASGLVEAGDNI
IIVAGVPVGTGRTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-76 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-76 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-76 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-77 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_001032433.1 pyruvate kinase VFG0479 Protein 5e-77 42