Gene Information

Name : Mpe_A0005 (Mpe_A0005)
Accession : YP_001019202.1
Strain : Methylibium petroleiphilum PM1
Genome accession: NC_008825
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 5980 - 7566 bp
Length : 1587 bp
Strand : +
Note : -

DNA sequence :
ATGCCGGACGACCTGAAGAGGACCCTCTGGGCCACCGCCGACAAGCTGCGCGCCAACATGGACGCGGCCGAGTACAAGCA
CCTGGTGCTGGGCCTGATCTTCCTGAAGTACATCTCCGACACCTTCCAGGCCCGCCGCACCGAACTGACGGCGCGCTTCG
CCGACCCGGCCGACGAATACCACCTCGACGGCGCCACGCCGGCCGACATCGCCGCCGAACTGGAAGACCGCGACTACTAC
CGCGAGGCCAACGTCTTCTGGGTACCGGAAGCGGCCCGCTGGGAAGCCATCCGTTCTGCGGCCAAGCAGCCCGACATCGG
CAAGCGCATCGACGATGCCCTGAGCCTCATCGAAGCCGAGAACCCCAAGCTCAAGGGCATCCTCGACAAGCGCTTCGCGC
GCGCGCAGCTGCCCGACGGCAAGCTGGGCGAACTGGTGGACCTGGTCTCCACCATCGGCTTCGGCGAGAGCGCCGCCACT
GCGCGCGACGTGCTGGGCCAGGTGTACGAATACTTCCTCGGCATGTTCGCCAGCGCCGAAGGCAAGCGCGGCGGTCAGTT
CTACACGCCGCGCAGCATCGTCAAGACACTGGTCGCCGTGCTGGCGCCGCACCACGGCAAGGTGTACGACCCGTGCTGCG
GCAGCGGCGGCATGTTCGTGCAGAGCGAAGAGTTCATCCTCAGCCACGGCGGCAAGCTGGGCGACGTGGCCATCTTCGGC
CAGGAGGCCAACCCCACCACTTGGCGGCTCGCGGCAATGAACCTCGCGATCCGCGGCATCGACTTCAACCTCGGCCGCGA
GCCGGCCGACACCTTCACCAAGAACCAGTTTCCCGACCTGCGCGCCGACTTCATCCTGGCCAACCCGCCGTTCAACATCA
GCGACTGGTGGCACGCGAGCCTGACGGGTGACGCTCGTTGGCACTACGGCGACCCGCCGCAAGGCAATGCCAACTACGCC
TGGCTGCAGCACATGCTGCACCACCTGAAGCCCGGCGGCCGCGCCGGCATCGTGCTGGCCAACGGCAGCATGAGCAGCAG
CCAGAACAACGAAGGCCAGATCCGCGCCGCGACGGTGGAGGCCGACGTGGTGGAGGTGATGATCGCGCTGCCGGGCCAGC
TGTTCTTCAACACGCAGATCCCGGCGTGCCTGTGGTTCCTGGTGAAGGACAAGCGGCAGCGCCGAGGCGAGGTGCTGTTC
ATCGACGCGCGCAAGCTGGCCACGATGATCAGCCGCGTGCAGTGCGAGCTGAAGGACGAGGTGATCGAGCGGATCGCCGG
GACCGTGGCCGCGTGGCGCGCATCACCCCCTCTCCCGCTGGCGGGAGGGGGTCGGGGTGAGGGTGCTTCGAGCTACGCCG
ACATCCCCGGCTACTGCCGCAGCGTGAAGCTCGCCGAGATCGCCGAGCACGGGCATGTGCTGACGCCGGGGCGCTATGTG
GGCGCGGAAGCGGTGGACGATGATGGCGAGAGCTTCGAGGCCAAGATGCAGGCGCTGACCGAGAAGCTCGGGGAGCAGAT
GGCGAAGGGGGCGGAGCTGGATGCGGTGATTCGGCAGAAGCTGGGTGGGCTCGGGTATGAGTTCTGA

Protein sequence :
MPDDLKRTLWATADKLRANMDAAEYKHLVLGLIFLKYISDTFQARRTELTARFADPADEYHLDGATPADIAAELEDRDYY
REANVFWVPEAARWEAIRSAAKQPDIGKRIDDALSLIEAENPKLKGILDKRFARAQLPDGKLGELVDLVSTIGFGESAAT
ARDVLGQVYEYFLGMFASAEGKRGGQFYTPRSIVKTLVAVLAPHHGKVYDPCCGSGGMFVQSEEFILSHGGKLGDVAIFG
QEANPTTWRLAAMNLAIRGIDFNLGREPADTFTKNQFPDLRADFILANPPFNISDWWHASLTGDARWHYGDPPQGNANYA
WLQHMLHHLKPGGRAGIVLANGSMSSSQNNEGQIRAATVEADVVEVMIALPGQLFFNTQIPACLWFLVKDKRQRRGEVLF
IDARKLATMISRVQCELKDEVIERIAGTVAAWRASPPLPLAGGGRGEGASSYADIPGYCRSVKLAEIAEHGHVLTPGRYV
GAEAVDDDGESFEAKMQALTEKLGEQMAKGAELDAVIRQKLGGLGYEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 4e-133 52
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-131 52
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 6e-133 52
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 3e-130 50