Gene Information

Name : Mpe_A2342 (Mpe_A2342)
Accession : YP_001021533.1
Strain : Methylibium petroleiphilum PM1
Genome accession: NC_008825
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 2510537 - 2512552 bp
Length : 2016 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGCGTGTTCCTGTGCGAGAAGCCGTCCCAGGGCAAGGACATCGCCCGTGTGCTGGGTGCCGGTCAACGCGGCAACGG
CTGCTACAGCGGCGCGGGTGTCGTCGTGACCTGGTGCATCGGTCATTTGGTGGAGGCGGTTCCGCCCGAAGGCTACGGCG
AGCAATACAAGCGCTGGGCCATCGAACAACTGCCTATTCTTCCTGAGCGTTGGCGTGTCGAGCCCAAGGCGGCGACCGCA
GCGCAATTCAAGGTCGTGCAGCAGCTCGTCGCCAAGGCGGGCGAGCTGGTGATCGCGACTGACGCCGACCGCGAGGGCGA
GATGATCGCCCGCGAGATCATCGACCTATGCGGCTACCGCGGGCCGATTCAGCGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCGATCCGCAAAGCGCTGGGTGCGCTCAAGCCGTCCGACGAGACGCTGCCGCTGTATTTCTCCGCACTCGCCCGATCG
CGCGCCGACTGGCTGATTGGGATGAACCTGAGCCGCTTGTTCACACTGCTGGGGCGCCAGGCCGGCTATACCGGCGTGCT
GTCGGTGGGGCGCGTGCAGACGCCGACGCTGAAGTTGGTCGTGGACCGCGATCGCGAGATCGCGCGATTCGTCTGCGTAC
CGTTCTGGGCCATCGAGGTTGCGCTTTCGCATGCAGGCCAGTCCTTCGTCGCAAGCTGGACGCCGCCGCAAGGCAGCGCC
GACGACGCCGACCGCTGCTTGCAGCAGCCGGTGGCGCAGCAGGCAGCGGAATTCCTGCGCGCGGCCGGCACCGCCCAGGT
GCTGTCGGTGGAGACCGAGCGCGTGCGCGAAGGGCCGCCGCTGCCGTTCGACCTGGGCACGCTGCAGGAGGTGTGCTCCA
AGCAGTTGGGCCTCGACGTGCAGGAGACGCTGGACATTGCCCAGGCGCTGTACGAGACGCACAAGGCGACAACGTATCCG
CGCTCGGATTCGGGCTACCTGCCCGAGAGCATGCTGGCCGAGGTGCCGACGGTACTCAACAGCCTGGTCAAGACCGACCC
CAGCTTGCGGCCGCTGATCGAGCGCCTGGATCGCCAACAGCGTTCGCGTGCATGGAACGACGGCAAGGTGTCGGCTCACC
ACGGCATCATCCCGACGCTGGAGCCCGCCAACCTGTCGGCCATGAACGAGAAGGAACTGGCCGTCTACCGGCTGATCCGC
GCTCATTACCTCGCGCAGTTCCTCCCACACCATGAGTTCGACCGGACGGTGGCGCAGTTCTCGTGCGGCAGTCAGTCGCT
GGCGGCCGTGGGCAAGCAGATCGCCGTCATCGGCTGGCGTGAGGTGCTGGCGACGCCGGGGCCGGACGATGCCGATGGCG
AGGATGCGCAGCGCAGCCAGGTGCTGCCCGCCCTGCATGCGGGCCTGTCCTGCCCGGTCGGAAAGGTGGATCTCAAGGCG
CTGAAGACGCTGCCGCCCAAACCCTACACGCAGGGCGAGCTGATCAAGGCCATGAAGACCGTCGCCAAGCTCGTGACCGA
CCCGCGCCTGAAGCAGAAGCTGCGAGATACCACCGGCATCGGCACCGAGGCGACACGCGCCAACATCATCAACGGTCTGA
TCGGTCGCGGCTACCTGGTCAAGAAAGGCCGCGCCGTCCGCGCTTCCGACGCGGCATTCACGCTCATCGACGCGGTGCCC
TCAGCCATCGCCGACCCCGGCACCACGGCGGTGTGGGAGCAGGCGCTCGACATGATCGAGGCCGGCCAGATGACGCTGGA
CACCTTCATCGAGAAGCAGTCCGTGTGGGTCGGCCAGCTCGTGCAGCAGTACCGCGGCGCAACGCTCTCGCTCAAGCTGC
CGCCGGCGCCGGCCTGCCCGCAGTGCGCCGCACCGATGCAGCAGCGCACGGGCAAGAGCGGCGCGTTCTGGTCCTGCTCG
CGCTACCCGGACTGCAAGGGCACGTTGCCGATCGAGTCCCCGACGGGCCGGCGCAGCGCACCGCGCAAGCGGCGCGCTGC
CTCCAAGGCGTCCTGA

Protein sequence :
MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWAIEQLPILPERWRVEPKAATA
AQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSDETLPLYFSALARS
RADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHAGQSFVASWTPPQGSA
DDADRCLQQPVAQQAAEFLRAAGTAQVLSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYP
RSDSGYLPESMLAEVPTVLNSLVKTDPSLRPLIERLDRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIR
AHYLAQFLPHHEFDRTVAQFSCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA
LKTLPPKPYTQGELIKAMKTVAKLVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLVKKGRAVRASDAAFTLIDAVP
SAIADPGTTAVWEQALDMIEAGQMTLDTFIEKQSVWVGQLVQQYRGATLSLKLPPAPACPQCAAPMQQRTGKSGAFWSCS
RYPDCKGTLPIESPTGRRSAPRKRRAASKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 80
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 79
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 65
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-161 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-161 51
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 7e-162 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-162 51
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 7e-163 50