Gene Information

Name : Mpe_A1610 (Mpe_A1610)
Accession : YP_001020807.1
Strain : Methylibium petroleiphilum PM1
Genome accession: NC_008825
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1737035 - 1738921 bp
Length : 1887 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCCCCCGACAAGCTCGCCACCCTGCTCTCGCTGACACGCGAGCCCTTCCCCGCCTCGCGCAAGTCCTATCTGCA
AGGCTCGCGCAGCGACCTGCGCGTACCGATGCGCGAAGTGACGCTGACCAACGGCGAGACCGTCTCGCTGTACGACACCT
CGGGTCCGTACACCGAACCCGGCGTCGCGATCGACGTGAGGCGCGGCCTGCCCAGCGTGCGCACGCCCTGGCTCGACGAG
CGTGCCGACACCGAGGTCTATGCCGGCCGGCTGCACCAGGCGCTGGACGACGGCGCGAAGCACGAGGACCGCGAGGCCGA
GCGCATCGAACAGTTGCGCCTCGACGCCGCAGCGCTGCAGCGGCCTCCGCGCCGTGCCAGGGCCGGCGCCAACGTCACGC
AGATGCACTATGCGCGCCGCGGCATCGTCACGCCCGAGATGGAGTACGTGGCGCTGCGCGAGAACGGCAAGCGCGAGTGG
ATGCGGGAGTACCTCGGCGACGCCCCGCGCGAACAGCGCCTGCGCGGCAACCCGATGGGTGCGCAGATCCCGGCCATCGT
GACGCCTGAGTTCGTGCGCGACGAGGTGGCGCGCGGCCGCGCCATCATCCCGGCCAACATCAACCACCCCGAAGTGGAGC
CGATGGCGATCGGCCGCAACTTCCTGGTGAAGATCAACGCCAACATCGGCAACTCGGCCGTCACGTCGAGCATCGAGGAA
GAGGTGGAGAAGCTGGTGTGGGCGATCCGCTGGGGCGCCGACAACGTGATGGACCTCTCCACCGGTCGCAACATCCACAC
CACGCGCGACTGGATCCTGCGCAACTCGCCGGTGCCGATCGGCACCGTGCCGATCTACCAGGCGCTCGAGAAGGTGGGCG
GCGTGGCCGAGGACCTCACCTGGGCCATCTTCCGCGACACGCTGATCGAGCAGGCCGAGCAAGGCGTCGACTACTTCACC
ATCCACGCCGGCGTACGCCTGCCCTTCATCCACCTCACCGCGGACCGCCGCACCGGCATCGTCTCGCGTGGCGGCTCGAT
CATGGCCAAGTGGTGCATCTCGCACCACCGCGAGAGCTTCATCTACGAGCACTTCGAGGACATCTGCGACATCATGAAGG
CCTACGACGTGAGCTTCTCGCTCGGCGACGGCTTGCGCCCCGGCTCGGCCGCCGACGCCAACGACGAGGCGCAGTTCGCC
GAACTGCGCACGCTGGGCGAGCTGACCCAGGTGGCCTGGAAGCACGACGTGCAGACCATGATCGAAGGCCCGGGCCACGT
GCCGATGCACATGATCCAGGCCAACATGGACGAGCAGCTCAAGCACTGCCACGAGGCGCCGTTCTACACGCTGGGGCCGC
TGACGATCGACATCGCGCCCGGCTACGACCACATCGCCAGCGCCATCGGCGCGGCCATGATCGGCTGGTTCGGCACCGCG
ATGCTGTGCTACGTGACGCCCAAGGAACACCTGGGCCTGCCCGACCGCGAGGACGTGAAGCAGGGCATCGTCGCCTACAA
GATCGCCGCGCACGCGGCTGATGTCGCCAAGGGTCACCCCGGCGCTCGCGCCCGCGACGACGCGCTGTCCAAGGCGCGCT
TCGAGTTCCGCTGGATGGACCAGTTCAACCTTTCGCTGGACCCCGACACCGCACGCGACTTCCACGACGAGACGCTGCCC
AAGGACGCCAGCAAGGTGGCGCACTTCTGCTCGATGTGCGGGCCCAAGTTCTGCTCGATGAAGATCACCCAGGAGGTGCG
CGACTACGCCGCGCAGCGCGGCGTCAGCGAGGCGCAGGCGCTGGGCGCCGGCATGGCCGAGAAGTCGAGCCAGTTCCGGC
AGGCCGGCGGCGAGATCTACATCCCGCTCGCCGTCGACAAGGGCTGA

Protein sequence :
MNAPDKLATLLSLTREPFPASRKSYLQGSRSDLRVPMREVTLTNGETVSLYDTSGPYTEPGVAIDVRRGLPSVRTPWLDE
RADTEVYAGRLHQALDDGAKHEDREAERIEQLRLDAAALQRPPRRARAGANVTQMHYARRGIVTPEMEYVALRENGKREW
MREYLGDAPREQRLRGNPMGAQIPAIVTPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFLVKINANIGNSAVTSSIEE
EVEKLVWAIRWGADNVMDLSTGRNIHTTRDWILRNSPVPIGTVPIYQALEKVGGVAEDLTWAIFRDTLIEQAEQGVDYFT
IHAGVRLPFIHLTADRRTGIVSRGGSIMAKWCISHHRESFIYEHFEDICDIMKAYDVSFSLGDGLRPGSAADANDEAQFA
ELRTLGELTQVAWKHDVQTMIEGPGHVPMHMIQANMDEQLKHCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWFGTA
MLCYVTPKEHLGLPDREDVKQGIVAYKIAAHAADVAKGHPGARARDDALSKARFEFRWMDQFNLSLDPDTARDFHDETLP
KDASKVAHFCSMCGPKFCSMKITQEVRDYAAQRGVSEAQALGAGMAEKSSQFRQAGGEIYIPLAVDKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 67
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 67
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 65