Gene Information

Name : Mpe_A1549 (Mpe_A1549)
Accession : YP_001020746.1
Strain : Methylibium petroleiphilum PM1
Genome accession: NC_008825
Putative virulence/resistance : Virulence
Product : ATP-dependent protease (heat shock protein)
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1669412 - 1672015 bp
Length : 2604 bp
Strand : +
Note : -

DNA sequence :
ATGCGTATCGACAAACTCACGACCAAGTTCCAGGAAGCGCTGGCCGACGCCCAGAGCCTCGCCGTCACGCGCGACAACCC
CTACATCGAGCCGGCCCACGTGCTGGCTGCGATGCTGGCGCAGACCGACGGCCCCAAGGCCTTGCTCGAGCGGGCTGGCG
CCAACACCGCGGCCCTGCGGACCGCGATGGACGTGGCCCTCAACGGACTGCCGCAGGTGCAGGGGGGCGGGCAGGGCGTG
CAGCCCGGCCGTGATTTCGTCACCCTGATGCAGGCGGCCGAGCGCGATGCCGCGAAGCGCGGTGACCAGTTCATCGCCAG
CGAGATGTTCCTGCTCGCCCTCGCCGATGCCAAGACCGACCTCGGCGGCATCGTGCGCGGCCACGGCCTCACCCGCAAGG
CGCTGGAGACCGCGATCGACGCGGTGCGCGGCGGCCAGAAGGTCGACAGCGCCGAGTCCGAGGGCCAGCGCGAGGCGCTG
AAGAAGTACACGCTCGACCTCACCGAGCGCGCCCGTGCCGGCAAGCTCGACCCGGTGATCGGCCGCGACGACGAGATCCG
CCGCGCGATCCAGGTGCTGCAGCGGCGCAGCAAGAACAACCCGGTGCTGATCGGCGAGCCGGGCGTCGGCAAGACCGCCA
TCGTCGAGGGGCTGGCGCAGCGCATCGTCGCCGGCGAGGTGCCCGAGTCGCTCAAGAGCAAGCGCGTGCTGGTGCTCGAC
ATGGCCCTGCTGCTGGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGGCTCAAGAGCGTGCTGAAGGAAGTGGCGCA
GGACGAGGGCCAGACCATCGTCTTCATCGACGAGATCCACACCATGGTGGGCGCCGGCAAGGCCGAGGGTGCGATCGACG
CCGGCAACATGCTCAAGCCCGCACTGGCGCGTGGCGAACTGCACTGCATCGGCGCCACCACGCTGGACGAATACCGCAAG
TACGTCGAGAAGGACGCCGCGCTCGAGCGCCGCTTCCAGAAGGTGCTGGTCGGCGAGCCCAGCGTCGAGGCCACCATCGC
CATCCTGCGCGGCCTGCAGGAGAAGTACGAGGTCCACCACGGCGTCGAGATCACCGACCCGGCGATCGTGGCCGCGGCCG
AGCTCTCGCACCGCTACATCACCGACCGCTTCCTGCCCGACAAGGCCATCGACCTGATCGACGAGGCCGCGGCCAAGGTC
AAGATCGAGATCGACTCCAAGCCCGAGGTGATGGACAGGCTCGACCGCCGGCTGATCCAGCTGAAGATCGAGCGCGAGGC
CGTGCGCAAGGAGAAGGATGAGGCCTCGCAGAAGCGCTTCGGCCTGATCGAGGAGGACATCGCCAAGCTGGAGCGCGAGG
CGGCCGACCTGGACGAGGTGTGGAAGGCCGAGAAGGCCACCGCCCAGGGCTCGGCCCACCTGAAGGAAGACATCGACCGC
ATCCGCACGCAGATCGAGGAGTTCAAGCGCAAGGGCGACTTCAACAAGGTCGCCGAGCTGCAGTACGGCAAGCTGCCGGA
GCTGGAGAAGAAGCTCAAGGACGCGCAGGCCAAGGAGGCCAAGGGCGGGGTCGATGGCAAGCCCACGCTGCTGCGCACGC
TGGTCGGCTCGGAAGAGATCGCCGAGGTGGTGGCGCGCGCCACCGGGATCCCGGTCGCCAAGCTGATGCAGGGCGAGCGC
CAGAAGCTTCTCGACATGGAAGTGAAGCTGCACGAGCGCGTGGTGGGCCAGGACGAGGCGATCCGCGCCGTGTCCGACTC
GATCCGTCGTTCGCGTGCCGGCCTGTCCGACCCGAACCGCCCGACCGGCTCCTTCCTGTTCCTCGGCCCCACCGGCGTCG
GCAAGACCGAGCTGTGCAAGGCGCTGGCCGGTTTCCTGTTCGACACCGAGGAAGCCATGATCCGCATCGACATGAGCGAG
TTCATGGAGAAGCACTCGGTCGCCCGCCTGATCGGCGCGCCGCCGGGCTATGTGGGCTATGACGAGGGGGGTTATCTCAC
CGAGGCAGTGCGCCGCAAGCCCTACAGCGTGCTGCTGCTCGACGAGGTGGAGAAGGCGCACCCCGACGTGTTCAACGTGC
TGCTGCAGGTGCTGGACGACGGCCGCCTGACCGACGGGCAGGGCCGCACGGTGGACTTCAAGAACACGGTGATCGTGATG
ACCAGCAACCTGGGCTCTCACCTCATCATGCAGATGGCGGGGCAGGACCCGGAGCTGATTCGCGAGGCGGTGTGGGGCGA
GCTGAAGACGCACTTCCGGCCGGAGTTCCTGAACCGCATCGACGAGACCGTGGTGTTCCATGCGCTCGACGCGCAGCACA
TCGAAGCGATCGCGGGCATCCAGCTCAAGGCGCTGGAGGCGCGTCTGGCCAAGCTGGACATCCGCCTCGAGGTGTCGGCG
GCGGCGCTGTCGGAGCTGGCGAAGGTGGGCTTCGATCCGGTGTTCGGGGCGCGGCCGCTGAAGCGGGCGATCCAGCAGCG
CATCGAGAACCCGCTGTCCAAGCTGCTGCTGGAGGGCAAGTTCGCGCCGAAGGACGTGGTGCCGGTCGACGTGGACCCGA
TCCGCTCGCCGGGCGAGTTCCACTTCGGGCGCGTGGTGCACTGA

Protein sequence :
MRIDKLTTKFQEALADAQSLAVTRDNPYIEPAHVLAAMLAQTDGPKALLERAGANTAALRTAMDVALNGLPQVQGGGQGV
QPGRDFVTLMQAAERDAAKRGDQFIASEMFLLALADAKTDLGGIVRGHGLTRKALETAIDAVRGGQKVDSAESEGQREAL
KKYTLDLTERARAGKLDPVIGRDDEIRRAIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVAGEVPESLKSKRVLVLD
MALLLAGAKYRGEFEERLKSVLKEVAQDEGQTIVFIDEIHTMVGAGKAEGAIDAGNMLKPALARGELHCIGATTLDEYRK
YVEKDAALERRFQKVLVGEPSVEATIAILRGLQEKYEVHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAKV
KIEIDSKPEVMDRLDRRLIQLKIEREAVRKEKDEASQKRFGLIEEDIAKLEREAADLDEVWKAEKATAQGSAHLKEDIDR
IRTQIEEFKRKGDFNKVAELQYGKLPELEKKLKDAQAKEAKGGVDGKPTLLRTLVGSEEIAEVVARATGIPVAKLMQGER
QKLLDMEVKLHERVVGQDEAIRAVSDSIRRSRAGLSDPNRPTGSFLFLGPTGVGKTELCKALAGFLFDTEEAMIRIDMSE
FMEKHSVARLIGAPPGYVGYDEGGYLTEAVRRKPYSVLLLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNLGSHLIMQMAGQDPELIREAVWGELKTHFRPEFLNRIDETVVFHALDAQHIEAIAGIQLKALEARLAKLDIRLEVSA
AALSELAKVGFDPVFGARPLKRAIQQRIENPLSKLLLEGKFAPKDVVPVDVDPIRSPGEFHFGRVVH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-106 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-102 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-102 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mpe_A1549 YP_001020746.1 ATP-dependent protease (heat shock protein) VFG2076 Protein 7e-117 45