Gene Information

Name : tktA (P9303_26081)
Accession : YP_001018603.1
Strain : Prochlorococcus marinus MIT 9303
Genome accession: NC_008820
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2301063 - 2303072 bp
Length : 2010 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGTCGCTGCGACTGCTTCCCTAGACACGCTCTGCATCAACAGCATTCGCATGCTGGCCGTCGATGCGGTCAACAAGGC
CAACAGCGGCCACCCTGGTCTTCCCATGGGCTGTGCCCCCATGGGCTACACCCTCTGGGACCAATTTCTGCATCACAACC
CCAAGAATCCTCAGTGGTTCAACCGCGACCGCTTTGTCCTCTCAGCCGGTCACGGCTGCATGTTGGTTTACTCGCTGTTG
CATCTCACCGGGTATGACTCGGTGAGCATCGAGGACATCAAGCAGTTCCGCCAATGGGGCTCCCGCACTCCTGGACATCC
CGAAACATTTGAAACCCCTGGGGTCGAAGTCACCGCAGGCCCCCTTGGTGCTGGGATCTCTAATGCCGTTGGCCTTGCGA
TCGCTGAAGCTCACCTTGCGGCCAAATTCAATAAACCCGAAGCAAAGATCGTTGATCACTTCACCTACGTGGTGATGGGC
GATGGCTGCAACCAAGAAGGTATTTCCTCTGAGGCCTGCTCCCTTGCCGGCCACCTCAAGCTAGGAAAACTGATCGCCCT
CTACGACGACAACCACATCACGATCGACGGCCGCACAGACGTTTCCTTCACCGAAGACGTTCTCAAGCGCTACGAGGCCT
ATGGCTGGCATGTACAACATGTCGCCAATGGCGACACCGACGTGAATGCCATCGCCAAGGCGATCGCTGCCGCCAAGGCC
GTGACCGATAAGCCTTCGATTATCAAGGTGACCACCACCATTGGTTACGGCTCCCCTAACAAAAGCGATACTGCCGGCGT
GCACGGGGCCCCCCTTGGCGAAGAAGAAGCCACTCTCACTCGCCAACAACTGGGATGGAACTATGGCCCTTTTGAAATTC
CCCAAGAGGCCTACGACCAATACCGCAAGGCCATCGATCAAGGCGCTCGCCTTGAATCTGAGTGGAATCAAGCACTCGCC
AACTACAGAAGTCAATACCCAAATGAAGCAGCTGAATTCGAGCGGATGTTGCGCGGTGAGCTTCCCAAGGGGTGGGACAA
AGATCTACCGACCTATACCCCTGAAGACAGTGGCCTCGCAACGCGTAAGCACTCCCAGATCTGCCTGGGCGCTCTAGGCC
CAAACCTACCGGAACTCATCGGCGGCTCTGCCGACCTCACTCACTCCAATTACACCGATATCAAAGGTGAAACCGGCTCC
TTCCAACCGGAAACACCCGAAAAGCGTTATCTACATTTCGGTGTGCGCGAGCACGCCATGGCCGCCATCCTCAATGGCAT
CGCTTACCACAACAGTGGCCTAATCCCCTACGGCGGAACCTTCCTAGTTTTTGCTGACTACATGCGCGGATCAATGCGCC
TTTCAGCCTTAAGTGAGCTTGGCGTGATCTACGTACTCACCCATGACTCAATCGGTGTGGGAGAAGACGGCCCGACCCAC
CAACCGGTCGAAACCATTCCCTCCCTGCGCGCCATGCCAAACATGCTGGTGTTCCGTCCCGGAGATGGTAATGAGACCAG
CGGAGCGTATAAATTAGCCATCCAGAATCGCAAACGCCCCAGCTCTCTTTGCCTGAGCCGTCAGGGCATGGCCAACCAAG
CCAATTCATCCATCGAAAATGTCGCTCTCGGCGGCTACGTACTGGAAGATTGCGAAGGAACAGCTGATCTGATCCTTATC
GGTACAGGCACAGAGCTTGACCTTTGCGTGCAAGCCGCCAAGCAACTCAGTGCTGCAGGCCACAAGATTCGCGTGGTCTC
GATGCCTTGCGTAGAACTTTTCGAAGAACAGAGCAGCGCATACAAACAAGAGGTGCTGCCAAACGCTGTACGCAAGCGCA
TCGTGGTGGAAGCCGCCGAATCATTTGGCTGGCACAAGTACATCGGCATTGATGGCGACAGTGTGACCATGAACAGCTTT
GGCGCTTCTGCACCAGGTGGCACATGCATGGAGAAGTTTGGCTTCACCGTAGAGAATGTGGTAGCGAAGTCAAAAGCGTT
GCTGAATTGA

Protein sequence :
MVAATASLDTLCINSIRMLAVDAVNKANSGHPGLPMGCAPMGYTLWDQFLHHNPKNPQWFNRDRFVLSAGHGCMLVYSLL
HLTGYDSVSIEDIKQFRQWGSRTPGHPETFETPGVEVTAGPLGAGISNAVGLAIAEAHLAAKFNKPEAKIVDHFTYVVMG
DGCNQEGISSEACSLAGHLKLGKLIALYDDNHITIDGRTDVSFTEDVLKRYEAYGWHVQHVANGDTDVNAIAKAIAAAKA
VTDKPSIIKVTTTIGYGSPNKSDTAGVHGAPLGEEEATLTRQQLGWNYGPFEIPQEAYDQYRKAIDQGARLESEWNQALA
NYRSQYPNEAAEFERMLRGELPKGWDKDLPTYTPEDSGLATRKHSQICLGALGPNLPELIGGSADLTHSNYTDIKGETGS
FQPETPEKRYLHFGVREHAMAAILNGIAYHNSGLIPYGGTFLVFADYMRGSMRLSALSELGVIYVLTHDSIGVGEDGPTH
QPVETIPSLRAMPNMLVFRPGDGNETSGAYKLAIQNRKRPSSLCLSRQGMANQANSSIENVALGGYVLEDCEGTADLILI
GTGTELDLCVQAAKQLSAAGHKIRVVSMPCVELFEEQSSAYKQEVLPNAVRKRIVVEAAESFGWHKYIGIDGDSVTMNSF
GASAPGGTCMEKFGFTVENVVAKSKALLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 8e-166 53
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-162 52