Gene Information

Name : lysS (P9303_01841)
Accession : YP_001016204.1
Strain : Prochlorococcus marinus MIT 9303
Genome accession: NC_008820
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 202932 - 204458 bp
Length : 1527 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGCGAGGTCAGTCCTGAGTGCCTTGTCTGAGCTGCGTGAGACTCGCCTGGAAAAGGCACAAGCCCTCAAAGAGCTGGG
GAATGGGCCTTATGCCCTGCGCTTTGAGTCAAGCCATCGCACCGCTAACTTGCAGGCGGATCATGCTGATTTGGCCAAGG
GGGAGGAGAGGCTTCTCAGTGTGTCTGTGGCTGGTCGGGTGATGGCCCGTCGTGTCATGGGCAAGTTGGCTTTCTATACC
TTGGCGGATGAGACCGGCACGATTCAGTTGTATTTGGACAAGGCCACCATTGATGCGGCTGCATCAAATGAGCTGGCTTC
AGGAACTTTTGTTCAGCTCACCACTCTTGTTGACGCGGGCGACTGGATTGGGGTCACAGGCGTGCTTCGTCGCACTGATC
GTGGTGAGCTTTCGGTGAAGGTTCAGCAGTGGCAGATCTTGAGCAAATCATTGCAACCCTTGCCGGATAAGTGGCACGGT
TTAGCTGATGTGGAGAAGCGCTATCGGCAACGCTATCTGGATCTAATCGTGTCGCCTCAGTCGCGTGAGACTTTTCGCCG
CCGGGCATTGATGGTGAGTGCAATCCGTCGATGGCTCGATGATCGCGCCTTCTTGGAAATCGAAACACCGGTGCTTCAGG
CTGAGGCCGGTGGCGCCGAAGCTAGGCCATTCATTACTCACCACAACACACTCGATCTTCCTCTTTATCTGCGTATTGCT
ACAGAGCTGCATCTCAAGAGGCTTGTGGTTGGTGGTTTTGAGCGGGTCTATGAGCTTGGGCGCATCTTTCGTAACGAGGG
GATGAGTACCCGCCACAACCCTGAATTCACTTCTGTAGAGGTCTATCAGGCCTATGCGGATTACATCGACATGATGGTCC
TTACTGAGCAGCTGATTTCCTCAGTTTGTACTCAGATCTGTGGGTCTACGAGGATCACTTATCAAGGTATAGAAATCGAC
CTAACGCCCCCTTGGCGGAGAGCCAGCATGCACGAACTGGTGCAAGAGGCGACGGGGCTTGATTTCATGGGTTTTGCTGA
CCGTGCGGTAGCGGCTTCGGCTATGGCGCGGGCAGGTCTAGAGGTTCCGTCTAAGGCCGATAGTGTGGGCCGCTTGCTTA
ATGAGGCCTTTGAACAAGCAGTGGAGGTAAGTCTGATCCAGCCAACATTTGTGCTCGATTATCCGATTGAGATCTCGCCT
CTTGCCCGACAACATCGCAGCAAACCAGGATTGGTCGAGCGCTTTGAATTGTTCATTGTGGGTCGGGAAACAGCCAATGC
TTTTAGTGAGTTAATCGATCCCCTTGATCAGCGTCAGCGGCTTGAGGCTCAGCAAGCACGTCGTCAGGCTGGGGACCTGG
AGGCTCATGGGGTTGATGAGGATTTTCTTCAGGCGCTTGAGGTGGGCATGCCCCCTACCGGCGGCTTGGGTATTGGCATC
GATCGCTTAGTGATGTTGTTCACCGATAGCCCGTCAATACGTGATGTGATTGCTTTCCCTCTGCTTCGACCGGAGCTCAA
AACTTAA

Protein sequence :
MARSVLSALSELRETRLEKAQALKELGNGPYALRFESSHRTANLQADHADLAKGEERLLSVSVAGRVMARRVMGKLAFYT
LADETGTIQLYLDKATIDAAASNELASGTFVQLTTLVDAGDWIGVTGVLRRTDRGELSVKVQQWQILSKSLQPLPDKWHG
LADVEKRYRQRYLDLIVSPQSRETFRRRALMVSAIRRWLDDRAFLEIETPVLQAEAGGAEARPFITHHNTLDLPLYLRIA
TELHLKRLVVGGFERVYELGRIFRNEGMSTRHNPEFTSVEVYQAYADYIDMMVLTEQLISSVCTQICGSTRITYQGIEID
LTPPWRRASMHELVQEATGLDFMGFADRAVAASAMARAGLEVPSKADSVGRLLNEAFEQAVEVSLIQPTFVLDYPIEISP
LARQHRSKPGLVERFELFIVGRETANAFSELIDPLDQRQRLEAQQARRQAGDLEAHGVDEDFLQALEVGMPPTGGLGIGI
DRLVMLFTDSPSIRDVIAFPLLRPELKT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-95 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001016204.1 lysyl-tRNA synthetase VFG1668 Protein 9e-96 46