Gene Information

Name : pykF (P9303_15431)
Accession : YP_001017552.1
Strain : Prochlorococcus marinus MIT 9303
Genome accession: NC_008820
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1344316 - 1346133 bp
Length : 1818 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGGTAGTTTCCGCGATGTTTCAGGTCCCGTTGATGGCCCAGATCGATCTGACACGACGGACCAAAATCGTTGCCACCAT
AGGTCCGGCAACCGAGACCGCCGAACGAATCCGAGAACTCGTTCAGGTAGGTGCTACCACCTTCCGGCTGAATTTCTCAC
ACGGCGACCATGACGAGCACGCCAAGCGCATCTCCACCATCCGCCAGGTCTCTGATGAATTGGGGATGCACATTGGCATT
CTTCAAGACTTGCAAGGCCCCAAAATTCGCCTGGGTCGTTTTGATAAGGGGCCTATCACTTTGGCCAATGGCGATCCCTT
CGCACTGACCTCAAAACAAGTTCAATGCAATCAGTCAGTGGCAACCGTCACTTACGAAAAGCTTGCAGACGAAGTCACGA
CCGGCAGTCGAATCTTGCTTGATGACGGTCGAGTGGAGATGAAAGTCGTAAAAATCGATCAAAGCGAACAAACCTTGCAC
TGCATCGTCACAGTGGGAGGGGTGCTCTCAAATAACAAGGGAGTGAATTTCCCTGATGTACAGCTATCGGTTCGCGCCCT
TACAGAGAAAGATCGCCAAGATCTCGCCTTTGGCCTCCAGCAAGGGGTGGACTGGGTCGCACTGAGCTTTGTGCGAAACC
CTTCGGACATGAAAGAGATCCGCAAACTCATCGGGGATCATGGGCACAGCACCCCAGTGATCGCGAAGATCGAGAAATTT
GAGGCGATTGATCAAATCGATTCAATCCTTCCTCTCTGTGATGGAGTCATGGTTGCAAGGGGGGACCTAGGCGTTGAGAT
GCCAGCCGAAGAGGTGCCTCTACTGCAAAAGGATTTGATTCGCAAGGCCAACAGCCTTGGAATTCCAATCATCACAGCCA
CCCAGATGCTCGACTCGATGGCCTCGAGCCCGAGGCCCACCAGAGCAGAAGTGAGTGATGTAGCAAATGCGATCCTTGAT
GGTACTGATGCAGTGATGCTCTCGAACGAAACCGCTGTAGGAGACTATCCAGTGGAGGCGGTTCAAACGATGGCCACCAT
TGCCAGACGGATTGAACGGGACTATCCACAGCGTCCAATCGAAACTTATCTTGCCAGCACCATTTCCAACGCGATTAGTT
CAGCCGTAAGCAGCATCGCCAGTCATCTCAACGCGGCAGCAATCGTGCCACTAACTGAAAGTGGTGCCACTGCCCACAAC
GTCAGCAAATTCCGCCCAGCAGCGCCAATTTTGGCCGTCACCAACGAAGTGGCTGTAGCAAGAAAACTTCAATTGGCATG
GGGTGTCACCCCACTGCTTGTCCCAACCCAGAAAAGCACCACTGCAACCTTCAGTGCTGCAATTGCTGTTGCCCAGGAAT
TGGGTCTTCTCAAAGAAGGAGATCTAACAATTCAAACTGCAGGAACCCTTGCTGGCGTGAGCGGGTCCACAGATCTTGTC
AAAGTAGGAATTGTCAGTGCAGTGCTTGGCCAAGGGATCGGTATTGGCAATGGCACCGTTAGCGGCAAGGTCAGATTTGC
TTTCTCCCCAAACGACTCAACAAAAATTGAACCAGGGGAGATTCTGGTCATTCATGAAACAAGCGATGACTATCTCGATG
CAATCAGAAAGTCTGCAGGAGTGATTACAGAACAAGAAGGAGAGGAATCCCACGCAGCCGTGATCTCAAAACGCCTAGGG
ATTCCGTTCATCATTGGGATAGCACATGCCACGAGAAACCTGCTTGAAGGAGAGGTGGTAACAATGCAGCTCAGTAATGG
CAAAGTTCATCGCGGCACAGGCGGCAAGCTGCCAATGAAGCTCGACTCAATGCTTTGA

Protein sequence :
MVVSAMFQVPLMAQIDLTRRTKIVATIGPATETAERIRELVQVGATTFRLNFSHGDHDEHAKRISTIRQVSDELGMHIGI
LQDLQGPKIRLGRFDKGPITLANGDPFALTSKQVQCNQSVATVTYEKLADEVTTGSRILLDDGRVEMKVVKIDQSEQTLH
CIVTVGGVLSNNKGVNFPDVQLSVRALTEKDRQDLAFGLQQGVDWVALSFVRNPSDMKEIRKLIGDHGHSTPVIAKIEKF
EAIDQIDSILPLCDGVMVARGDLGVEMPAEEVPLLQKDLIRKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILD
GTDAVMLSNETAVGDYPVEAVQTMATIARRIERDYPQRPIETYLASTISNAISSAVSSIASHLNAAAIVPLTESGATAHN
VSKFRPAAPILAVTNEVAVARKLQLAWGVTPLLVPTQKSTTATFSAAIAVAQELGLLKEGDLTIQTAGTLAGVSGSTDLV
KVGIVSAVLGQGIGIGNGTVSGKVRFAFSPNDSTKIEPGEILVIHETSDDYLDAIRKSAGVITEQEGEESHAAVISKRLG
IPFIIGIAHATRNLLEGEVVTMQLSNGKVHRGTGGKLPMKLDSML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-77 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-78 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-78 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_001017552.1 pyruvate kinase VFG0479 Protein 3e-78 44