Gene Information

Name : leuS (P9303_15061)
Accession : YP_001017515.1
Strain : Prochlorococcus marinus MIT 9303
Genome accession: NC_008820
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1306499 - 1309135 bp
Length : 2637 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGACGGAGTCTTTCCCCTCAACGTCTGCCTCCAGCCACTCCTCAGCTCGATATGACCCTATTGAGCTTGAAACGCGTTG
GCAAAAGGAGTGGTTACGACAAGGATTAGATCGAACGCCAGTCGCTGAAACTAACCAGAAACGCTTTTACGCCCTGTCGA
TGTTTCCTTATCCATCAGGGAAACTGCACATGGGCCACGTACGCAATTACGTGATTACCGATGTGATTGCCAGGGTGCAG
CGCATGCGCGGTGATGCGGTACTTCACCCAATGGGATGGGATGCCTTTGGCTTACCAGCTGAGAATGCAGCCATTGCCAG
AAACGTGGATCCAGGTGATTGGACAGACCAAAATATTGCCCAAATGAGGGCCCAGCTTGATCGGCTGGGCTTGTCGATTG
ACTGGGACCGGCAACAGGCGACTTGCCATCAGGACTATTACCGCTGGACCCAGTGGTTGTTCCTTGAACTTTTTGCGGGT
GGACTGGCTTATCAGAAGGAAGCGACAGTCAACTGGGATCCCATCGACAAAACTGTTCTGGCTAATGAACAGGTAGATGG
CGAGGGTCGTTCATGGCGATCAGGCGCTCTTGTGGAACAGCGACAACTCAAGCAATGGTTCCTGCGAATCACCGACTATG
CCGATGCGTTAATTGATGACCTTGATGAATTGACTGGTTGGCCCGAGCGTGTCCGCACGATGCAAGCCAATTGGATTGGT
CGCTCTCATGGTGCTGAAATTAAGTTCAGAGTTGCTGGTCAGACCAACTCAATCATCACGGTCTTCACAACAAGGCCAGA
CACACTTCACGGTGCCAGCTATGTGGTTTTGGCACCTGAGCACCCCTTGGTTGAAGCCCTAACAAGTCCGCAACAACGTA
TTGCCGTTACTGCATTCTGTGACCTTATAAGCCAACTCAGCGTCAAAGATCGCACCGCTGAGGACCAACCAAAACGTGGG
GTCCCGATCGGTGCACAGGTGATCAACCCAGTGAATGGTGAATCACTACCAGTTTGGATTGCCGATTACGTATTGGCTGA
CTATGGCTCAGGAGCAGTCATGGGAGTACCCGCTCATGATGAGAGGGATTTCATCTTTGCTCGCAGCCACGAACTACCGA
TACGCATTGTGGTTCAGATGCCAGATTCAGACGAGCATCACAATGATGGACAAGCCTGGACCGGAGCCGGAGTACTTGTA
AATTCCGGAGCCTTTGATGGTCTCTCCACAGAGGAAGGGAAGGTTGCGATTACAACCCATGGTGCGTCTAAGGGTTGGGC
TCAAAGCAAAGTTCAATACCGTTTGCGCGATTGGCTTATTTCGCGTCAGCGCTACTGGGGTTGCCCGATTCCAATCATTC
ACTGTGCAAGCTGTGGAATCGTTCCTGTTCCGCAAGAGGACCTCCCTGTAACCCTTCCTAGGGACATAGATCTTTCAGGA
AAAGGAGGATCCCCCTTAGCTCAAGAACAGGATTGGGTTGAGGTGAAATGTCCTATTTGTGGTGAAAAGGCTCACAGGGA
AACAGACACGATGGACACCTTTATGTGTTCTTCATGGTATTACCTACGTTTTGCTGATCCACTCAATAGTCAACGTCCAT
TTGACAAAGATATTGTTGATGAATGGTTGCCTGTTGATCAATATGTAGGTGGTATTGAACATGCAATCCTCCATCTCCTA
TATGCACGCTTTTTCACCAAAGCACTCCACGATAGAAACTTGATTGGCTTTAAAGAACCATTTAATACATTGCTTACTCA
AGGGATGGTTCAAGGGCTCACCTACCGCAATACTAAAAATGGCAGTTATATTTCTCCTGAACTTGTTAGTGATGAAGGTG
ATCCGAGGGACCCAGAGTCTGGAGATAAGCTAGAGATCCTGTTTGAAAAAATGTCTAAATCTAAATATAATGGCGTTGAT
CCTGCCGTTGTAATCGACCGATACGGTGCTGATACCGCTAGAATGTTCATTCTTTTTAAAGCGCCACCAGAGAAAGATCT
GGAATGGGACGATGCAGATGTTGAAGGCCAATTTCGTTTTCTGCAACGACTTATTCGTCTGATTGATAGCTTTGTATGGC
CTAAAACTGATGAGGATAATGCCTCCATTTCTTCCGCAAACTTGACGATATCTTCAGCTGATCTCAGTGAAGAAGAGATC
AATATGAGAAGAGCTACTCACATGGCGATAGAAGCAATAACTGAGGATTTAAGTGGAGATATTCAATTGAATACAGCTAT
CTCCGAACTCATGAAGCTATCTAACTCCTTGGGTGGAAAACTAGATAAGGTTCGTACTGAAGTGGCTGCAGAGGCTCTTT
CTGTTTTAGTTCGATTAATGGCACCCTTTGCTCCTCACCTTGCAGAAGAATTTTGGATGAAGCTTCATGGGCAAGGAAGC
ATCCATCAACAATCCTGGCCTATAATCGACCCAAGCGCACTTGTACTCGAAACAATTGAGCTCGTCATTCAAGTCAAAGG
TAAGGTACGTGGAACAATCCAGGTTCCTGCTAACGCAGACAAAACGGCATTAGAAGAATTGGCCTTAAAGAGTGACATCG
CCGTTAAATGGTTAGAGGGTCAATCGCCTAGACGGGTCATCATTGTTCCAGGCAAGTTGGTGAACCTAGTGCCATAG

Protein sequence :
MTESFPSTSASSHSSARYDPIELETRWQKEWLRQGLDRTPVAETNQKRFYALSMFPYPSGKLHMGHVRNYVITDVIARVQ
RMRGDAVLHPMGWDAFGLPAENAAIARNVDPGDWTDQNIAQMRAQLDRLGLSIDWDRQQATCHQDYYRWTQWLFLELFAG
GLAYQKEATVNWDPIDKTVLANEQVDGEGRSWRSGALVEQRQLKQWFLRITDYADALIDDLDELTGWPERVRTMQANWIG
RSHGAEIKFRVAGQTNSIITVFTTRPDTLHGASYVVLAPEHPLVEALTSPQQRIAVTAFCDLISQLSVKDRTAEDQPKRG
VPIGAQVINPVNGESLPVWIADYVLADYGSGAVMGVPAHDERDFIFARSHELPIRIVVQMPDSDEHHNDGQAWTGAGVLV
NSGAFDGLSTEEGKVAITTHGASKGWAQSKVQYRLRDWLISRQRYWGCPIPIIHCASCGIVPVPQEDLPVTLPRDIDLSG
KGGSPLAQEQDWVEVKCPICGEKAHRETDTMDTFMCSSWYYLRFADPLNSQRPFDKDIVDEWLPVDQYVGGIEHAILHLL
YARFFTKALHDRNLIGFKEPFNTLLTQGMVQGLTYRNTKNGSYISPELVSDEGDPRDPESGDKLEILFEKMSKSKYNGVD
PAVVIDRYGADTARMFILFKAPPEKDLEWDDADVEGQFRFLQRLIRLIDSFVWPKTDEDNASISSANLTISSADLSEEEI
NMRRATHMAIEAITEDLSGDIQLNTAISELMKLSNSLGGKLDKVRTEVAAEALSVLVRLMAPFAPHLAEEFWMKLHGQGS
IHQQSWPIIDPSALVLETIELVIQVKGKVRGTIQVPANADKTALEELALKSDIAVKWLEGQSPRRVIIVPGKLVNLVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-163 43