Gene Information

Name : clpB (NATL1_06361)
Accession : YP_001014463.1
Strain : Prochlorococcus marinus NATL1A
Genome accession: NC_008819
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.4.21.92
Position : 575221 - 577812 bp
Length : 2592 bp
Strand : -
Note : COG714 MoxR-like ATPases [General function prediction only]

DNA sequence :
ATGAAGGTAAATCCTGATGATTTCACTAACATTGCTTGGCAAGGGATTATTGATGCAAAAGATTTAGCATTAACTGAAAA
ACATCAGACTTTAGAGACAGAACATCTTTTTTGGTCCCTTCTAAAGAAAAATGAAATAGCAATAAAAATAATAGAAAGAT
CAGGCGGAGTAATAAAAAATCTACTCACAGAAATAGAGAATTTCATAAAGAACCAACCAAAAATGCTACAGGCCCAAGAA
TCTATTTTCTTTGGCAAAAATATATCTTTATCAATTTCAAGAGCAAAAAACATTCAACAATCTTTCAAAGATGATTTTAT
TTCAAGCGAACATTTAGTGATTTCCCTATTTGATGACGAGAGAATTTGTAATAGGTTATTTGGACAAAATCATGTCGACA
AAAACAGCCTTCTTGAGGCTATAAATGTTCTTAGAGGTGACAAAAAAGTGACCCAGAAAAATGCTGAGAATAGCTACGAA
GCTCTTCAAAAGTACGGATTAGACCTTACTTCTGCCGCCAGAGATGGAAAATTAGATCCTGTAATTGGAAGAGATGAGGA
GATACGAAGAACGATTCAAATACTAAGCCGCAGAACCAAAAATAATCCTGTGTTAATTGGAGAAGCTGGCGTTGGCAAAA
CAGCAATTATTGAGGGTTTAGCACAAAGAATTATCAACGGTGATGTTCCTACAGCTCTTGAGAACCGTCAACTAATTTCT
TTAGACATGGGGGCACTAATAGCAGGTGCAAAATTTCGTGGTGAATTTGAAGAGAGACTTAAGTCAGTTCTTAAAAATGT
CACAGATTCAGAAGGGAAAATAATTTTGTTCATCGATGAAATACATACTGTCGTCGGAGCAGGAGCGAGTGGTGGAGCTA
TGGACGCTAGCAATCTCCTAAAACCAATGCTTGCTAGAGGTGAACTGAGATGCATTGGAGCAACAACCATAAATGAACAT
AGAGAAAATTTTGAGAAAGACCCTGCGCTGGAAAGAAGATTTCAGCAAATACTTGTAAAACAACCCTCAGTCCAAGATAC
AATTTCGATCTTACGTGGACTAAAAGAAAGATATGAAGTCCATCATGGTGTTCGTATCTCTGATAACGCTCTAATAGCTG
CGGCGATATTGAGCGATAGATATATACCAGAGAGGTTTTTACCTGACAAAGCAATTGATCTAATAGATGAATCAGCCTCA
CGTTTAAAGATGGAAATAACATCAAAACCAGAAGAAATTGACGAGATTGATAGAAAAATCATCCAACTTGAGATGGAGAA
ATTATCTTTAGAAGGTGAGTCAGACACATCAAGTAAAGAGAGATTAGAATTAATTACTACAGAACTAGCATTGCTAACAA
AAAATCAAATTGAAGTAACAAAAAAATGGAAACAAGAAAAAGAATCAATCGAAGAAATTTCAACACTTAAAGAAGACATT
GAGAAAGTACAACTAGAAATAGAAAAAGCAAAAAGAAATTATGACCTAAATAGAGCTGCTGAACTTGAATACGGCACCCT
TGTGAATTATCAACAAAATTTAAAATCTAAAGAACTTAATCTAAAAAATTCCACTGAAAATGCGGAAAAATCACTTTTGA
GAGAAGAGGTTTTAGCCGATGATGTAGCTGAAATAATTGCAAAGTGGACATCTATTCCCGTTAAAAGATTGGCTCAAACT
GAAATTGAAAAATTACTCAATCTTGAATCTCAGCTTCAAAAAAGAGTTATTGGTCAAGATAAAGCCGTTCAATCAATATC
TTCTGCGATACAAAGATCTAGGACAGGACTTAGTGATCCAAGCAGACCAATCGCAAGTTTTTTATTTTTAGGACCGACAG
GCGTGGGGAAGACAGAATTGTCCAAGGCTTTGGCTTCTCAACTTTTTGATAGTGAAAATGCCTTAATCAGAATAGACATG
TCTGAATATATGGAAAAGCACTCTATAAGTCGCTTAATTGGCGCTCCTCCTGGTTACGTTGGTTACGAAGCAGGTGGGCA
ATTAACAGAAGCAATCAGAAGAAAACCTTATTGCGTTTTGCTCTTCGATGAAATTGAAAAAGCACATAAAGATGTTTTCA
ATGTATTGCTTCAGATACTTGACGAAGGCCGAGTAACTGATGGACAAGGTAGAACAACAAATTTCAAAAACACTATTATT
ATTCTCACAAGTAATTTAGGAAGCGAATTAATCTCTGATAATGATGTAACTAATGATCCGTCGACAAATATAGATGAACT
TATTAATCAAGAGCTGAAATCAAATTTCAGGCCTGAGTTCCTAAACAGACTTGATGAAATAATTAATTTTGAACCACTAA
AAAAAGAAACACTACTTAAAGTAGTCGATTTACAATTAAACCGTTTAAGAGAAAGGTTAGAAGCTAAAGGAATCGAGCTT
GAAATTAATGATGATGTCCTATCTTTGATTACTGAACTTGGATACAACCCAAGCTATGGTGCTAGGCCCTTAAAAAGAGT
TATTCAAAAAGAATTAGAAAGTGAAATAGCAAAATATATTCTTAAAGGCAAATATAAAGAAGGAAGCACTATAAAGATTG
AGAGTAAAGAATCAAAATTAATTTTCCACTAA

Protein sequence :
MKVNPDDFTNIAWQGIIDAKDLALTEKHQTLETEHLFWSLLKKNEIAIKIIERSGGVIKNLLTEIENFIKNQPKMLQAQE
SIFFGKNISLSISRAKNIQQSFKDDFISSEHLVISLFDDERICNRLFGQNHVDKNSLLEAINVLRGDKKVTQKNAENSYE
ALQKYGLDLTSAARDGKLDPVIGRDEEIRRTIQILSRRTKNNPVLIGEAGVGKTAIIEGLAQRIINGDVPTALENRQLIS
LDMGALIAGAKFRGEFEERLKSVLKNVTDSEGKIILFIDEIHTVVGAGASGGAMDASNLLKPMLARGELRCIGATTINEH
RENFEKDPALERRFQQILVKQPSVQDTISILRGLKERYEVHHGVRISDNALIAAAILSDRYIPERFLPDKAIDLIDESAS
RLKMEITSKPEEIDEIDRKIIQLEMEKLSLEGESDTSSKERLELITTELALLTKNQIEVTKKWKQEKESIEEISTLKEDI
EKVQLEIEKAKRNYDLNRAAELEYGTLVNYQQNLKSKELNLKNSTENAEKSLLREEVLADDVAEIIAKWTSIPVKRLAQT
EIEKLLNLESQLQKRVIGQDKAVQSISSAIQRSRTGLSDPSRPIASFLFLGPTGVGKTELSKALASQLFDSENALIRIDM
SEYMEKHSISRLIGAPPGYVGYEAGGQLTEAIRRKPYCVLLFDEIEKAHKDVFNVLLQILDEGRVTDGQGRTTNFKNTII
ILTSNLGSELISDNDVTNDPSTNIDELINQELKSNFRPEFLNRLDEIINFEPLKKETLLKVVDLQLNRLRERLEAKGIEL
EINDDVLSLITELGYNPSYGARPLKRVIQKELESEIAKYILKGKYKEGSTIKIESKESKLIFH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-101 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-101 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_001014463.1 ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB VFG2076 Protein 2e-122 42