Gene Information

Name : guaA (NATL1_00351)
Accession : YP_001013864.1
Strain : Prochlorococcus marinus NATL1A
Genome accession: NC_008819
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 35154 - 36740 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCTTCAATGATTTCAGCTGAAAAACGTAATCCAGCAATTGTAATTCTCGATTTTGGTTCTCAATATTCAGAATTAAT
TGCTCGAAGGATTAGAGAGACAGAGGTTTACTCATTAGTTATGAGTTACACAACATCTGCTGACAAATTACGTTCACTTA
AGCCTAAGGGAATTATTTTAAGCGGAGGTCCTGGATCTGTTTATGAAGAAGGTGCTCCATATTGTGACCCAGAGATTTTT
AATTTAGGAATTCCTGTTCTTGGTGTTTGTTATGGAATGCAATTAATGGTTCATGAGCTAGGAGGATCTGTAAAACCTGC
TACTGGGAAAGCCGAATATGGAAAGGCTCCTTTAGAAGTTGATGATCCAACAGCGTTATTAACGAATGTTATTAGTGGTT
CAACAATGTGGATGAGTCATGGTGATTCAGTTCAGAAATTACCCAAAGGATTTGTCAGATTAGCTCATACCTCGAATACT
TTAGAGGCTGCTATTGCTTTGCATGATAAGAGCTTTTATGGAGTGCAATTTCATCCCGAAGTTGTTCATTCCACCCATGG
AATGGTTGTAATAAGAAATTTTGTATATGATATTTGTTCTTGTGAGCCGGATTGGACAACAAATTTATTTATAGATGAAG
CTGTTTCTCAAGTGCAACAACAGGTAGGCGATAAAAAAGTTTTATTGGCTCTATCTGGTGGTGTTGATTCATCAACTCTT
GCATTTTTGTTAAACAAAGCAATAGGACCTCAATTGACGTGCATGTTTATTGATCAAGGTTTTATGAGAAAAGGTGAGCC
AGAATTTTTAATGTCTTTTTTTGATGAAAAGTTCAAGATTAATGTTGAATACATCAATGCCAGAGAAAGATTTATTTCAC
AATTAAAAGGAGTAACTGATCCTGAGCAAAAGCGTAAAATTATAGGTAGAGAATTTATTCGGGTTTTTGAAGAAGAGAGT
CTGCGATTAGGCCCTTTTGATTACTTGGCTCAAGGTACGCTTTATCCAGATGTAATTGAAAGTTCTGGAACAAATATTGA
TCCAAAAACTGGCGAACGAATAGCGGTTAAAATTAAAAGTCATCATAATGTAGGAGGGTTGCCAAAAGATTTGCAATTTA
AATTGGTAGAGCCCTTGAGACGTTTATTTAAAGATGAAGTCAGAAAAGTTGGTAAATCACTGGGATTGCCAGATGAGATT
GTTCGAAGACACCCATTTCCAGGTCCAGGATTGGCTATAAGAATTTTAGGAGAGGTTACTCATGAGAAACTAAATTGTTT
AAGAGACGCAGATTTAATTGTCAGAGAGGAGATTAATAATGCTGGCTTGTATAACAAAATTTGGCAGGCGTTCGCAGTTT
TATTGCCTGTGTATTCAGTGGGAGTAATGGGAGATCAAAGAACTTATGCGTGGCCAATTGTTGTTCGTTGTGTTTCTAGT
GAGGATGGGATGACTGCTGATTGGTCGCGTTTGCCGTATGCAGTTTTAGAGAAAATTTCTAACCGGATAGTTAACGAGGT
CGAGGGAGTTAATAGAGTTGTTTTAGATATAACAAGTAAACCCCCAGGAACTATTGAGTGGGAGTGA

Protein sequence :
MASMISAEKRNPAIVILDFGSQYSELIARRIRETEVYSLVMSYTTSADKLRSLKPKGIILSGGPGSVYEEGAPYCDPEIF
NLGIPVLGVCYGMQLMVHELGGSVKPATGKAEYGKAPLEVDDPTALLTNVISGSTMWMSHGDSVQKLPKGFVRLAHTSNT
LEAAIALHDKSFYGVQFHPEVVHSTHGMVVIRNFVYDICSCEPDWTTNLFIDEAVSQVQQQVGDKKVLLALSGGVDSSTL
AFLLNKAIGPQLTCMFIDQGFMRKGEPEFLMSFFDEKFKINVEYINARERFISQLKGVTDPEQKRKIIGREFIRVFEEES
LRLGPFDYLAQGTLYPDVIESSGTNIDPKTGERIAVKIKSHHNVGGLPKDLQFKLVEPLRRLFKDEVRKVGKSLGLPDEI
VRRHPFPGPGLAIRILGEVTHEKLNCLRDADLIVREEINNAGLYNKIWQAFAVLLPVYSVGVMGDQRTYAWPIVVRCVSS
EDGMTADWSRLPYAVLEKISNRIVNEVEGVNRVVLDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-136 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-136 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-130 53