Gene Information

Name : lysS (NATL1_20701)
Accession : YP_001015890.1
Strain : Prochlorococcus marinus NATL1A
Genome accession: NC_008819
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1713935 - 1715476 bp
Length : 1542 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGTTGTATGTACCCATTGCCTTGTCTGAATTAAGAGATACCCGCCTCGAGAAGGCAAAAGCACTAAAAACCCTTGGGAA
AGGTCCCTATGGTTTGAATTTTCGACCTACTGACTCTGCCGCTGTTTTGCAGGGAAAATATAAAGACTTGCCAAATGGCG
AAGAAAAAAAAGACGAAGTATCTATTGCAGGGCGAGTAACTTCTAGAAGAGTGATGGGGAAACTTGCTTTTTTTACTCTT
TCCGATGAAACAGGCATAATTCAACTCTTTTTGGAAAAGGCGACCTTAAATCGGAATGAAGATAGTGAGAATCCAAAGAA
TAATTTTGAGAACATTACCTCTCTGGTTGACTCTGGTGATTGGATAGGAGTCAGTGGAATATTAAGGAGAACTGATAGAG
GTGAACTTTCTATAAAGGTTTTCGAATGGTCAATGCTATCAAAATCTTTACAACCCCTACCAGATAAATGGCATGGACTT
GCCGATGTAGAAAAGCGCTATAGACAAAGATATTTAGATTTAATTGTAAATCCACAGTCAAGAAAAACTTTTCGAACTAG
GGCTTTATTAGTTAGTTCAATTCGACGTTGGTTAGATGAAAAAGACTTTCTTGAAATCGAGACTCCAGTTTTACAATCAG
AAGCTGGAGGAGCGGATGCAAGGCCTTTCATAACTCATCACAACACGCTCGATTTACCTTTGTATCTGAGGATTGCAACA
GAATTGCATCTTAAAAGACTTGTGGTGGGTGGATTTCAAAGGGTCTATGAACTTGGAAGAATTTTTAGAAATGAAGGGAT
TAGCACTAGGCATAATCCTGAATTTACTTCTGTTGAAATTTATGAGGCCTTTGCAGATTATTTCGACATGATGGATTTAA
CAGAAAAATTACTTTCTTCAGTTTGCGAAAAGATTTGTGGATCGACCAAAATTAATTATCAAGAGCAAGAAATAGATTTG
CAACCTCCTTGGAGAAGGGCCACGATGCATGACTTAGTTAAGGAATTTACTGGAATAGATTTTGAATTATTTGGAGACAA
TGCTGATGATGCTAAGGCTGAAATGAGTCGAGAGGGGCTTCAAGTGCCCGATAAGGCTGATACTGTTGGAATCCTATTAA
ATGAAGCTTTTGAACAAGCAGTAGAGCCTGAGCTGATTCAGCCTACATTTGTGATGGATTATCCAATTGAGATTTCTCCA
TTGGCTAGAAAACACAGAACTAAAAAAGGTTTAGTGGAAAGATTTGAACTTTTTATTGTTGGTAGAGAAACTGCCAATGC
TTTTAGCGAATTAATTGACCCTATTGATCAAAGAGAACGTTTACTTTTACAGCAAGCGAAAAAAGAAGCAGGTGATCTTG
AGGCTCAAAGCTTGGATGAGGATTTTATCAATGCTCTTGAAGTCGGAATGCCTCCAACAGGAGGTCTCGGAATAGGAATA
GATAGGTTTGTAATGTTGTTAACAGATAGTCCTTCCATAAGAGATGTAATAGCTTTTCCACTTTTACGACCAGAAGCAAA
TTTAAAACAAACTGGAAAGTGA

Protein sequence :
MLYVPIALSELRDTRLEKAKALKTLGKGPYGLNFRPTDSAAVLQGKYKDLPNGEEKKDEVSIAGRVTSRRVMGKLAFFTL
SDETGIIQLFLEKATLNRNEDSENPKNNFENITSLVDSGDWIGVSGILRRTDRGELSIKVFEWSMLSKSLQPLPDKWHGL
ADVEKRYRQRYLDLIVNPQSRKTFRTRALLVSSIRRWLDEKDFLEIETPVLQSEAGGADARPFITHHNTLDLPLYLRIAT
ELHLKRLVVGGFQRVYELGRIFRNEGISTRHNPEFTSVEIYEAFADYFDMMDLTEKLLSSVCEKICGSTKINYQEQEIDL
QPPWRRATMHDLVKEFTGIDFELFGDNADDAKAEMSREGLQVPDKADTVGILLNEAFEQAVEPELIQPTFVMDYPIEISP
LARKHRTKKGLVERFELFIVGRETANAFSELIDPIDQRERLLLQQAKKEAGDLEAQSLDEDFINALEVGMPPTGGLGIGI
DRFVMLLTDSPSIRDVIAFPLLRPEANLKQTGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-103 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001015890.1 lysyl-tRNA synthetase VFG1668 Protein 1e-103 47