Gene Information

Name : tktA (NATL1_20621)
Accession : YP_001015882.1
Strain : Prochlorococcus marinus NATL1A
Genome accession: NC_008819
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1706093 - 1708105 bp
Length : 2013 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGTTGCCTTGACTACTTCCCTAGACACACTTTGCATCAACAGCATCAGGATGCTCGCTGTTGATGCAATTAATAAATC
CAAAAGTGGTCACCCAGGTTTACCTATGGGTTGCGCACCTATGGGTTATGCATTATGGGACAAGCACTTACGACACAATC
CAAAAAACCCGAAATGGTTTAATCGAGACAGATTTGTTCTTTCAGCGGGACATGGATGCATGCTTTTGTATGCTCTCTTG
CATTTGACTGGCTATGACTCTGTCACCATTGAAGATATAAAAGAATTTAGACAGTGGGGAGCTAAAACTCCAGGGCATCC
AGAAACCTTCGAAACTCCGGGAGTTGAAGTAACTGCAGGACCTTTGGGAGCAGGAATTTCAAATGCAGTTGGATTAGCTA
TTGCGGAAGCTCACCTTGCTGCAAAATTCAACAAACCTGATTCAACAGTTGTAGACCATTACACCTATGTGATCATGGGG
GATGGATGTAATCAAGAAGGTATTTCCTCAGAAGCATGTTCTCTTGCTGGGCATTTAAAACTTGGAAAATTAATAGCTCT
CTATGACGATAATCACATAACTATTGATGGAAGAACTGATGTCTCATTTACAGAGGATGTCTTAAAAAGATATGAAGCAT
ATGGATGGCATGTACAAGAAATTCCTGAGGGGAATACAGATGTTGAAGGCATATCTCAAGCAATCGAAAAGGCCAAATCA
GTCACTGATAAGCCATCCATCATCAAAGTAACAACAACTATCGGTTACGGTTCTCCAAATAAAAGTGATACTGCAGGTAT
TCACGGCGCCCCATTGGGCGAAGAAGAGGCAGAGCTCACTAGAAAACAATTAGGTTGGTCATACAAACCTTTCGAGGTTC
CCCAAGATGCTTATGATCAATATCGACAAGCCATTCAAAAAGGTGCACAGCTAGAAGAAGAGTGGAATCAAAGCCTAGCT
AAATACAAAGAAAAATATCCTAATGAAGCAACTCAATTTGAGCGCATGTTGAGAGGTGAGCTCCCTGAAGGCTGGGATAA
AGATTTACCTACCTATACATCCGATGATAAAGGGGTTGCTACTAGAAAACATTCTCAAATATGTCTAGGTGCTCTTGGTC
CAAACATCCCTGAACTAATAGGAGGTTCTGCTGATTTAACTCATTCAAACTACACAGATATAAAAGGAGAAACTGGATCT
TTTCAATATGAAAGTCCTGAAAAACGTTATTTACATTTTGGTGTCAGAGAGCATGCTATGGCAGCCATATTGAATGGCAT
TGCTTATCACGACAGTGGTTTAATTCCTTATGGTGGAACCTTCTTAGTCTTCGCAGATTACATGAGAGGATCGATGCGTC
TTTCTGCTCTTAGTGAGCTTGGAGTTATTTATGTTTTAACCCATGATTCCATAGGTGTTGGTGAAGATGGCCCAACACAT
CAACCTATAGAAACCATCCCATCATTGAGAGCAATGCCAAATATGATGGTTTTCCGTCCTGGCGATGGCAATGAAACCAG
TGGTGCTTATAAAGTTGCAATTAAAAATCGTAAGAGACCAAGTTCCTTATGCCTAAGTAGGCAGGGTATGGCAAATCAAC
AAAATTCATCCGTAGACAAAGTTGCTTTAGGTGGATATGTACTTGAGGAGTGCGATGGCACCCCAGAACTAATACTTATC
GGAACCGGAACTGAACTTGATTTATGTGTTCAAGCAGCGAAAAAGTTAACTAAGGAAGGTCGAAAAGTGCGTGTTGTTTC
TATGCCATGCGTTGAACTTTTTGAAGAACAAAGCGATAGTTATAAAGAAGAAGTTTTGCCTTCAAATATCAGAAAACGCC
TAGTAGTTGAAGCCGCAGAGAGTTTCGGATGGCACAAATATATTGGTCTTGATGGTGACAGCGTAACTATGAATAGCTTT
GGAGCATCTGCTCCAGGTGGATTATGTATGGAAAAATTTGGATTTACAGTTGAAAACGTACTAGAAAAATCTAAAAGTCT
GCTCAACAAATAA

Protein sequence :
MVALTTSLDTLCINSIRMLAVDAINKSKSGHPGLPMGCAPMGYALWDKHLRHNPKNPKWFNRDRFVLSAGHGCMLLYALL
HLTGYDSVTIEDIKEFRQWGAKTPGHPETFETPGVEVTAGPLGAGISNAVGLAIAEAHLAAKFNKPDSTVVDHYTYVIMG
DGCNQEGISSEACSLAGHLKLGKLIALYDDNHITIDGRTDVSFTEDVLKRYEAYGWHVQEIPEGNTDVEGISQAIEKAKS
VTDKPSIIKVTTTIGYGSPNKSDTAGIHGAPLGEEEAELTRKQLGWSYKPFEVPQDAYDQYRQAIQKGAQLEEEWNQSLA
KYKEKYPNEATQFERMLRGELPEGWDKDLPTYTSDDKGVATRKHSQICLGALGPNIPELIGGSADLTHSNYTDIKGETGS
FQYESPEKRYLHFGVREHAMAAILNGIAYHDSGLIPYGGTFLVFADYMRGSMRLSALSELGVIYVLTHDSIGVGEDGPTH
QPIETIPSLRAMPNMMVFRPGDGNETSGAYKVAIKNRKRPSSLCLSRQGMANQQNSSVDKVALGGYVLEECDGTPELILI
GTGTELDLCVQAAKKLTKEGRKVRVVSMPCVELFEEQSDSYKEEVLPSNIRKRLVVEAAESFGWHKYIGLDGDSVTMNSF
GASAPGGLCMEKFGFTVENVLEKSKSLLNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-170 53
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-161 50