Gene Information

Name : leuS (NATL1_09941)
Accession : YP_001014817.1
Strain : Prochlorococcus marinus NATL1A
Genome accession: NC_008819
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 913884 - 916472 bp
Length : 2589 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGAATAATACTACTTCAGATATTAATGACCAGCGATACGAGCCTCGGGAAGTAGAAGCTTATTGGCAAAAAGAATGGGC
TAATGATGACCTCTATAGGACAAATACTGAGGTAAATAAAGAAAATACTTTCTATGCCTTGTCGATGTTTCCATACCCAT
CAGGTTCTTTACATATGGGTCACGTAAGGAATTATGTAATTACTGACGTGCTCGCTAGATATAAAAGGATGAAAGGTTTA
AACGTCCTACATCCAATGGGTTGGGATTCCTTCGGATTACCTGCTGAAAATGCAGCAATAGAGAGAGAAACAAGTCCATC
GACATGGACAGATAAAAATATTTCACAAATGAAAGATCAATTAGATCGTCTAGGACTATCAATAGATTGGTCTAAAGAAG
TTACTACTTGCAAAGAAGACTATTATAAATGGACTCAATATATATTTAATCAATTACATAAAAATAATCTTGCCTATCAA
AAAAAAGCAACAGTTAATTGGGATCCAATTGATCAAACTGTTCTTGCTAATGAGCAAGTAGACGCTGAAGGTAAATCATG
GAGATCTGGAGCTAAAGTTGAGAAAAAAGAATTAAATCAGTGGTTTTTACGAATTACTAGTTTCGCCGAAGATCTTAATA
AGGATTTAGTTACGCTTAATGACTGGCCAGATAGAGTAAGAGTTATGCAAAAAAATTGGATTGGTAAATCCATCGGAGCA
GAAATAACATTTGATATCAAAAATAGCGACCAAAAAATAACAGCTTTCACAACAAGAATAGATACTGTTTATGGAGTAAG
TTATCTGGTATTAGCATCAAATCATCCATTAATTGATCAATTAATAAGTTCTAATGATATAGATAAATTAAATGACTTTA
GACAAACTCAAGAAAAGTTAAGTGATCTTGAACGTAATTCAGATACCAGACAAAAACTTGGAATGTACTTAGGAGTAGAT
GCAATTAATCCAGCAAATAATAAAGAGATACCGATTTGGATAGGAGACTATGTGATTATGGAATATGGAACTGGTGCTGT
GATGGGTGTTCCAGCTCACGATAGTAGAGATTATCAGTTTGCGAAATCATATGATTTACCAATTCAATATGTAATAAAAC
CTAATATTGGTGAAGATGAAAGTTATTTAAATGCTGAATTTGTTGATAAGGGAGTCATGATCAATTCAGATAAATTTAAT
GGTATTGAATCTGATATTGCAAAAACAAAAATACTTGAATTTGGTTCAAATTCAAATTGGGCAAAACCAAAGATCACATA
CAAATTAAGAGATTGGCTTATATCTAGACAACGATATTGGGGCTGCCCAATTCCGATTATTAATTGTAAGAAGTGTGGCC
AAGTAAGAGTCCCTGACGATGATCTTCCAGTTGTATTACCAATTGATATTAAATTAACTGGTAAAGGTAAGAGTCCTTTA
ACAACCAAAACCGAATGGATAAATACTTGTTGCCCAAAATGTGGAACTGATGCAAAAAGAGAAACTGATACAATGGACAC
TTTTATGTGTTCATCTTGGTACTTTTTAAGATATATAAACCCTGATAATTGTGAAAAGCCTTTTCTGAAAAGCGAAATAG
ACAAATGGCTTCCAGTTAAGCAGTATGTCGGTGGTATCGAGCACGCTATTTTACATTTACTATATTCTAGATTTTTAACC
AAGGCTCTCAAGAGATGTGGATTAATAAATATCGATGAACCTTTTAAGAAACTGCTAACTCAAGGGATGGTTCAAGCCGT
TACTTTTAAAAATCCCAATACAAATAAATATTTTTCAAAGGATCAAATTAAAGATATTGATAATCCTAAAGATCCACTTA
CAGGAGAGAATATTGAAATCATCTATGAAAAGATGTCGAAGTCAAAATACAATGGTGTAGATCCATCTGTAGTGATAGAT
AAATATGGAGCTGACACAGCAAGAATGTTTATTCTTTTTAAAGCTCCACCGGAAAAAGATTTAGAGTGGGATGACTCCGA
TGTCGAAGGTCAATACCGATTTATACAGAGACTCTGGAAATTTGTTATTAATACCTTTAAACTAACAAATAATAATTCAA
GATCTAATATAGAAAAAGAAAAGTCTAAAGACGAAGAGGCTTTACGCCTAATTAATATTGCTATTAAGGAAATTACTGAT
GATTTGGATAATCTTCAATTTAATACAGCAATATCTGAACTTATGAAGGTTGTAAATGGCCTAAGTTTAATAGTTAATTA
CTGTAGTAATGAAACACTAAATAAAGTTATTTCAATATTAGTTAAAATAACTTCTCCATTTTCTCCTCATATTGCAGAGG
AGCTTTGGAAGACAATTGGAAATACCCAAAGTATTCATCTTCAGTCATGGCCAGAATTTGATGCAGGTGCAATTGAACAA
GATACTTTTAAACTTATGATTCAAATCAATGGAAAAGTTAGAGGATCAATTAATGCTAGTAAAAATCTATCTAAAGAAAA
TTTAGAGGACTTAGCTATTAAAACTGAGGCTGCTATAAAATGGATGGATGGAAAAGAACCAAAACGAATAATTGTTGTCC
CGAATAAATTAGTAAATATAGTTATTTAG

Protein sequence :
MNNTTSDINDQRYEPREVEAYWQKEWANDDLYRTNTEVNKENTFYALSMFPYPSGSLHMGHVRNYVITDVLARYKRMKGL
NVLHPMGWDSFGLPAENAAIERETSPSTWTDKNISQMKDQLDRLGLSIDWSKEVTTCKEDYYKWTQYIFNQLHKNNLAYQ
KKATVNWDPIDQTVLANEQVDAEGKSWRSGAKVEKKELNQWFLRITSFAEDLNKDLVTLNDWPDRVRVMQKNWIGKSIGA
EITFDIKNSDQKITAFTTRIDTVYGVSYLVLASNHPLIDQLISSNDIDKLNDFRQTQEKLSDLERNSDTRQKLGMYLGVD
AINPANNKEIPIWIGDYVIMEYGTGAVMGVPAHDSRDYQFAKSYDLPIQYVIKPNIGEDESYLNAEFVDKGVMINSDKFN
GIESDIAKTKILEFGSNSNWAKPKITYKLRDWLISRQRYWGCPIPIINCKKCGQVRVPDDDLPVVLPIDIKLTGKGKSPL
TTKTEWINTCCPKCGTDAKRETDTMDTFMCSSWYFLRYINPDNCEKPFLKSEIDKWLPVKQYVGGIEHAILHLLYSRFLT
KALKRCGLINIDEPFKKLLTQGMVQAVTFKNPNTNKYFSKDQIKDIDNPKDPLTGENIEIIYEKMSKSKYNGVDPSVVID
KYGADTARMFILFKAPPEKDLEWDDSDVEGQYRFIQRLWKFVINTFKLTNNNSRSNIEKEKSKDEEALRLINIAIKEITD
DLDNLQFNTAISELMKVVNGLSLIVNYCSNETLNKVISILVKITSPFSPHIAEELWKTIGNTQSIHLQSWPEFDAGAIEQ
DTFKLMIQINGKVRGSINASKNLSKENLEDLAIKTEAAIKWMDGKEPKRIIVVPNKLVNIVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-160 41