Gene Information

Name : hemC (Hbut_0836)
Accession : YP_001013032.1
Strain : Hyperthermus butylicus DSM 5456
Genome accession: NC_008818
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 832447 - 833358 bp
Length : 912 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAAGCTCCGCGTAGCTACGCGGGGTAGTAAGCTCAGCATAGCACAGACAATGATAGCTCTGGAGGCAATAAAACGTGT
CGAGCCAAGCCTAGAGTATGAACTAGTGATAGTCAAGACTAGAGGTGATATACACCAGGACAAACCATTTACAGCTATAG
GCGGCAAGGGCCTCTTCGAGAAAGAGGTAAACCTTGCAGTACTGGAGGGACGTGCTGACATAGCAGTTCACAGTCTAAAG
GATGTACCTAGCGCTATTTCGCCCGGTCTAGTACTAGCCATGACGCCGCCGAGGGATCCACCCTACGACGTGCTCGTTGT
GAGAGGCGGGAAGGAGAAGACGATATGGGATCTGCCCAGCGGCGCTATCGTTGGAACATCGAGCGCCCGTAGGGTTGCAA
TGCTCAAACATGTCCGCCGCGACCTAGTCTTCAAGGTTTTAAGGGGTAATGTGGATACCAGGCTTCGAAAGCTAGAGCAA
GGACAGTATGACGCCATAGTGCTTGCCGAGGCCGGGCTAAAGAGGCTAGGTGTAGACATAGAGTATTGGCGTATACCTCC
AGACATCCTGCCCCCAGCGCCTGGCCAGGGCATAATAGGGGTCTATACTCTGTCCAGTCGCAGCGACATACTCCCGATCC
TCGAGAAGGCCTCAGACCAGAAGGCTATGGCCGAGGCTAGGGCTGAGAGAGCATTCCTAGCCTATGCTGGCGGTGGCTGC
CACACCCCACTCGGAGCCTACGCTGAGCTGCGTGGCAACACCCTCTACTTCCATGCAGCATTAGCATCTCCCGATGGCAG
CCGAAGGGTTGAAGTAAGGGTCGAGGGTGATCCGGATAAGCCTACACAGGTAGGCCTAGAGGCAGCATTCGAGCTGAGGA
GGCTAGCAGCAAGGGAGGGGATAAGCCTGTAA

Protein sequence : 
MKLRVATRGSKLSIAQTMIALEAIKRVEPSLEYELVIVKTRGDIHQDKPFTAIGGKGLFEKEVNLAVLEGRADIAVHSLK
DVPSAISPGLVLAMTPPRDPPYDVLVVRGGKEKTIWDLPSGAIVGTSSARRVAMLKHVRRDLVFKVLRGNVDTRLRKLEQ
GQYDAIVLAEAGLKRLGVDIEYWRIPPDILPPAPGQGIIGVYTLSSRSDILPILEKASDQKAMAEARAERAFLAYAGGGC
HTPLGAYAELRGNTLYFHAALASPDGSRRVEVRVEGDPDKPTQVGLEAAFELRRLAAREGISL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-41 42
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-41 42