Gene Information

Name : hemC (P9515_05591)
Accession : YP_001010875.1
Strain : Prochlorococcus marinus MIT 9515
Genome accession: NC_008817
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 498406 - 499356 bp
Length : 951 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGACTAAATTAAAATTAAAGATAGCTAGTAGAAGAAGTAAATTAGCAATGGTTCAAACATTATGGGTTAAAGAGCAATT
AGAAAAAAATATTCCTAACTTGGAAGTATCCATAGAGTCCATGGCAACACAAGGGGATAAAATTCTCGATGTGGCATTAG
CAAAAATAGGAGATAAAGGACTTTTTACAAAAGAACTTGAAGCTCAAATGCTCATTGGTAAAGCGGACATTGCGGTGCAT
TCTTTAAAAGATTTGCCAACCAACTTACCTGACGGACTAAAATTAGGATGTATAACAAAAAGAGAAGATCCTTCTGATGC
TCTAGTAGTTAATAAAAAAAATGAAATTTATCAATTAGAGAGTCTTCCCGCGGGTTCAATTGTTGGAACTAGTTCTCTTA
GGAGACTGGCTCAATTAAGGTACAAATTCCCATATCTTAATTTCAAAGACATCAGGGGAAATGTTATTACAAGAATAGAA
AAGTTAGATTCCGGAGAATTTGATTGTATTATTCTTGCTGCAGCGGGTTTAAAAAGATTGGGATTTGAATCAAGAATACA
CCAAATTATTCCTAACGAGATTTCCCTCCATGCAGTTGGGCAAGGGGCTTTAGGAATAGAATGTAAATCTGAGGATAAAG
AAGTTCTAAAAATTATAAGTGTCTTAGAAGATAAGGCCTCAAGCCAAAAATGTTTAGCAGAGAGATCTTTTTTAAGAGAA
CTTGAAGGTGGATGTCAAGTTCCAATTGGAGTTAATAGTAGTATTCAAAATGATGAAATATGCCTAAAAGGAATGGTCGC
ATCTATTGATGGGAAAAAACTTATTAAGGATGAATCAAGTGGAAATGTTAAATATCCAGAGGAAGTTGGTAAAAAACTAG
CTGAAAAGCTGAAACTTCAAGGAGCAGATAAAATTCTCTCGGAAATATTTGAACAATTTAGGGATAAATAA

Protein sequence :
MTKLKLKIASRRSKLAMVQTLWVKEQLEKNIPNLEVSIESMATQGDKILDVALAKIGDKGLFTKELEAQMLIGKADIAVH
SLKDLPTNLPDGLKLGCITKREDPSDALVVNKKNEIYQLESLPAGSIVGTSSLRRLAQLRYKFPYLNFKDIRGNVITRIE
KLDSGEFDCIILAAAGLKRLGFESRIHQIIPNEISLHAVGQGALGIECKSEDKEVLKIISVLEDKASSQKCLAERSFLRE
LEGGCQVPIGVNSSIQNDEICLKGMVASIDGKKLIKDESSGNVKYPEEVGKKLAEKLKLQGADKILSEIFEQFRDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-60 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-60 49