Gene Information

Name : guaA (A9601_00361)
Accession : YP_001008431.1
Strain : Prochlorococcus marinus AS9601
Genome accession: NC_008816
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 34778 - 36364 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGTCAAACATCTTTAAAAAAAGAACGAGATCCTTCAATATTAATTTTAGATTTTGGATCTCAATATTCTGAATTGAT
TGCAAGAAGAATTAGAGAAACTAATGTTTTCTCTCTTGTAGTGAGTAATTTTATTTCAATTGAGGATATTAATAGAATTA
ATCCTAAAGGGATCATATTGAGTGGAGGCCCAAATTCTGTATATGAACAAAATGCTCCCAGATGTGATGAAAAAATTTTT
AATTTAGGAATTCCTATTCTTGGCATATGCTATGGAATGCAATTAATGGTCAAGGAACTTGGAGGAACTGTTATTTCAGC
AACCAAAAAAGCTGAATATGGTAGAGCACCACTAAATATAGATCAAGAATCTGACCTTCTTTTTGATGTAGAAGATAAAT
CTATAATGTGGATGAGTCATGGCGATTCAATTAATTGTTTGCCTGATGGATTTAATAAGATTGCTCATACCGAGAACACA
CTCCATGCAGCAATTTCAAATGATGTAAAGAAATTATTTGGCGTACAATTTCATCCTGAAGTTGTTCATTCAGAATTTGG
AATGAGGGTAATTAAAAATTTTGTTTATAAAATTTCTTGTTGTACGGCTGATTGGACAACCGAAACATATATAGAAGAAA
CTATTCCAAGAATAAGAGAGCAAGTTGGCAACAAAAAAGTATTGCTTGCTTTATCAGGGGGAGTTGATTCCTCAACTCTT
GCCTTTCTTCTTAATAAAGCAATTGGAAATCAGCTTACTTGCATGTTTATAGATCAAGGTTTCATGAGAAAAGGTGAACC
AGAATTTTTAATGAATTTTTTTGATAAGAAATTTCACATTAAAGTTGAATACATTAATGCAAGAGAAAGGTTTATTGCCA
AATTAAAAGGAATTACTGATCCAGAACAAAAAAGAAAAATTATTGGTGAAGAATTTATTAGAGTATTTGAAGAGGAAAGT
AATAGATTGGGACCTTTTCAGTATTTAGCTCAAGGTACTCTATATCCTGATGTTATTGAAAGTGCTGGTACTAATATTGA
TCCTAAGACAGGTGAGAGGATAGCTGTAAAAATAAAGAGTCATCATAATGTAGGTGGATTGCCAAAAGATTTACAATTTA
AATTAGTTGAGCCATTAAGAAAACTTTTTAAGGATGAAGTTCGAAAAGTCGGCGCTGCTTTAGGTTTGCCAGATGAAATT
ATAAAAAGGCATCCATTCCCAGGACCTGGATTAGCTATAAGAATTTTGGGAGAGGTGAATAATGAAAAACTTGATTGTTT
AAGAGATGCAGACTGGATAGTAAGAGACGAAATTAAAAAAGCAGGTCTTTACAACGATATTTGGCAAGCTTTTGCAGTAT
TGTTACCTGTAAAAACTGTAGGAGTTATGGGTGATAAAAGGACTTATTCATGGCCAATAGTTTTACGTTGTGTATCAAGT
GAAGATGGCATGACAGCTGATTGGTCAAAAATTCCTTTTCAGATTTTGGAGAGGATTGCTAATAGAATAGTAAATGAAGT
AATTTCAGTTAATAGAGTTGTTTATGATATTACAAGCAAACCTCCTGGAACTATTGAGTGGGAATAA

Protein sequence :
MSQTSLKKERDPSILILDFGSQYSELIARRIRETNVFSLVVSNFISIEDINRINPKGIILSGGPNSVYEQNAPRCDEKIF
NLGIPILGICYGMQLMVKELGGTVISATKKAEYGRAPLNIDQESDLLFDVEDKSIMWMSHGDSINCLPDGFNKIAHTENT
LHAAISNDVKKLFGVQFHPEVVHSEFGMRVIKNFVYKISCCTADWTTETYIEETIPRIREQVGNKKVLLALSGGVDSSTL
AFLLNKAIGNQLTCMFIDQGFMRKGEPEFLMNFFDKKFHIKVEYINARERFIAKLKGITDPEQKRKIIGEEFIRVFEEES
NRLGPFQYLAQGTLYPDVIESAGTNIDPKTGERIAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRKVGAALGLPDEI
IKRHPFPGPGLAIRILGEVNNEKLDCLRDADWIVRDEIKKAGLYNDIWQAFAVLLPVKTVGVMGDKRTYSWPIVLRCVSS
EDGMTADWSKIPFQILERIANRIVNEVISVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-139 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-128 50