Gene Information

Name : mrfD (YE0782)
Accession : YP_001005123.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Virulence
Product : pili chaperone protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 908141 - 908908 bp
Length : 768 bp
Strand : +
Note : Similar to Photorhabdus luminescens mannose resistant fimbriae MrfD SWALL:Q93MT3 (EMBL:AF396083) (249 aa) fasta scores: E(): 1.3e-67, 69.91 38d in 246 aa, and to Escherichia coli chaperone protein PapD precursor papD SWALL:PAPD_ECOLI (SWALL:P15319) (239 a

DNA sequence :
ATGAATTCGAAGGAAAAAGTAATGAAATTGAATAACAAATTGCGTATCACCACCATTTTGGTGACGGCACTGATGACTCA
GCAAGCAACAGCAGCGATTGCACTGGACAGAACCCGGGCCATTCTTAATGGTGGCGATAAGTCGATCAGCTTGAATATCA
GCAACCAGAATAAGGAATTACCTTATCTGGCGCAGGGATGGATTGAAGATGAGCAGGGTAACAAAATCAATTCACCGTTG
ACTGTCGTACCTCCGGTTCAGCGGGTAGAACCGGGCGCGATGAGCCAGTTAAAAATACAAAGTTTGCCTGCGGTGAATCA
GTTGGCGCAAGACCGGGAAACCTTGTTCTATTTTAACCTGCGCGAAATCCCACCACGGTCGGACAAGCCCAATACTTTGC
AGATTGCATTGCAAACGCGCATCAAACTTTTCTACCGCCCTGCGGGTATCGTGCCACAAAAGGCCGATATGTCGACACCT
TGGCAAGAGAAGTTACAGCTGACTCGTCAGGGTGATCGCTATCAGGTTAATAACCCGACGCCGTATTACATCACGCTGGT
CGATGCCAGTGAGAGCAAAACTGGCAAAACGGCAGCAGGTTTCAAACCGCTGATGATTGCACCAAAAGCGCAGGGCATGT
TGGATGTGAGTGCTGCGGCATTAGGTAGCAAGCCAGTGCTGACTTATGTCAACGATTTCGGCGGTCGTCCAAAACTGATC
TTCGGCTGTTCGGGTAGCACGTGTTCTGTGGTGGAAAGTATCAAATAA

Protein sequence :
MNSKEKVMKLNNKLRITTILVTALMTQQATAAIALDRTRAILNGGDKSISLNISNQNKELPYLAQGWIEDEQGNKINSPL
TVVPPVQRVEPGAMSQLKIQSLPAVNQLAQDRETLFYFNLREIPPRSDKPNTLQIALQTRIKLFYRPAGIVPQKADMSTP
WQEKLQLTRQGDRYQVNNPTPYYITLVDASESKTGKTAAGFKPLMIAPKAQGMLDVSAAALGSKPVLTYVNDFGGRPKLI
FGCSGSTCSVVESIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
papD NP_755464.1 PapD protein Virulence PAI I CFT073 Protein 3e-51 50
pixD CAE85158.1 PixD protein Not tested PAI V 536 Protein 4e-60 49
prfD CAD42028.1 PrfD protein Virulence PAI II 536 Protein 2e-58 49
papD_2 NP_757033.1 PapD protein Virulence PAI II CFT073 Protein 4e-58 49
papD YP_002414014.1 Chaperone protein PapD Not tested Not named Protein 4e-58 49
papD YP_854253.1 pilus assembly protein chaperone PapD Virulence PAI I APEC-O1 Protein 4e-58 49
papD AAL67413.1 PapD Virulence PAI II CFT073 Protein 3e-58 49
papD AAZ04423.1 P pilus chaperone Virulence PAI I APEC-O1 Protein 3e-58 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mrfD YP_001005123.1 pili chaperone protein VFG0885 Protein 1e-51 50
mrfD YP_001005123.1 pili chaperone protein VFG1547 Protein 1e-58 49
mrfD YP_001005123.1 pili chaperone protein VFG0896 Protein 2e-58 49