Gene Information

Name : murD (YE0670)
Accession : YP_001005019.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 774180 - 775514 bp
Length : 1335 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGTTGATTATCAGGGTAAGAAAGTCGTCATTATCGGGCTGGGGCTAACCGGCCTTTCCTGCGTTGATTTCTTCATTGC
GCGTGGCGTAACGCCGCGTGTGATGGATACCCGTATCAATCCACCGGGCCTGGATAAATTACCCGAAAATGTCGAGCGTC
ATGTTGGTGACTTGAATCAGCAGTGGTTATTGGATGCTGATTTGATTGTTGCCAGCCCCGGTATTGCGTTGGCACATCCT
GCTTTGAGTGAAGCCGCGGAAGCAGGTGTTGAGATTGTCGGCGATATCGAGCTGTTCTGTCGTGAAAATCAGGCACCGGT
GGTAGCGATTACCGGCTCTAACGGTAAAAGTACCGTAACCACTCTGGTCGGCGAGATGGCGAAAGCGGCTGGCTGGCAGG
TTGGCGTAGGGGGAAATATTGGTGTTCCTGCTCTTAACTTACTGAAACAGTTGACCTTGCAAAAACACGAAAATCAATTG
GTGGTGTTGGAATTATCCAGCTTCCAGTTGGAAACCACCTCAAGCTTGCATGCCAGTGCGGCCACCATACTGAACGTGAC
GGAAGATCATACTGACCGTTATCCGTTCGGTTTGCAGCAATATCGCGCAGCTAAGCTGCGGGTATATGAAAACGCTAAAG
TTTGTGTCGTGAATGCCGATGACGCGCTCACTATGCCGGTGCGTGGCGCTGATAACCGCTGTATCAGCTTTGGCGTGGAT
GTCGGTGACTACCATCTGAATAAGCAGCAGGGAGAAATCTGGCTGCGGGTTCGGGGTGAAAAAGTCTTGAATACCCGCGA
AATGAAATTGACCGGTCGCCATAACTATACCAATGCGCTAGCCGCACTGGCATTGGCTGATGCCGTAGGGATTCCGCGCT
CATCAAGTTTGAAAGCGCTGACCACGTTCACTGGTTTGCCGCACCGTTTCCAATTGGTGTTTGAACACAACGGCGTGCGT
TGGATTAACGACTCCAAAGCCACCAACGTGGGCAGCACAGAAGCGGCTCTGGATGGTTTACCGCTTGATGGCACTTTGCA
TTTGTTACTGGGCGGCGACGGGAAATCGGCAGATTTCTCCGGGTTGACCCGTTTTTTGCAAGGCGACCATATCAAGATTT
ACTGTTTTGGGCGTGATGGTGAGCAACTGGCTGAGCTGCGTCCGGAAGTGTCGCAACTGACTGAAACGATGGAACAAGCC
ATGGTGCTGCTGGCTAAATCACTGGCACCGGGCGATATGGTGTTATTGTCACCCGCTTGCGCCAGCTTGGATCAGTTCCG
CAGCTTCGAACAACGTGGTGATGAGTTTGCTCGTCTGGCAGAGGAGTTGGGCTGA

Protein sequence :
MVDYQGKKVVIIGLGLTGLSCVDFFIARGVTPRVMDTRINPPGLDKLPENVERHVGDLNQQWLLDADLIVASPGIALAHP
ALSEAAEAGVEIVGDIELFCRENQAPVVAITGSNGKSTVTTLVGEMAKAAGWQVGVGGNIGVPALNLLKQLTLQKHENQL
VVLELSSFQLETTSSLHASAATILNVTEDHTDRYPFGLQQYRAAKLRVYENAKVCVVNADDALTMPVRGADNRCISFGVD
VGDYHLNKQQGEIWLRVRGEKVLNTREMKLTGRHNYTNALAALALADAVGIPRSSSLKALTTFTGLPHRFQLVFEHNGVR
WINDSKATNVGSTEAALDGLPLDGTLHLLLGGDGKSADFSGLTRFLQGDHIKIYCFGRDGEQLAELRPEVSQLTETMEQA
MVLLAKSLAPGDMVLLSPACASLDQFRSFEQRGDEFARLAEELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 7e-58 42
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 7e-58 42