Gene Information

Name : ysaV (YE3546)
Accession : YP_001007704.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Virulence
Product : type III secretion system apparatus protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 3862139 - 3864211 bp
Length : 2073 bp
Strand : -
Note : Previously sequenced as: Yersinia enterocolitica YsaV SWALL:O30436 (EMBL:AF005744) (690 aa) fasta scores: E(): 0, 100 38d in 690 aa. Also similar to Salmonella typhimurium, and Salmonella typhi invasion protein InvA inva or stm2896 or sty3019 SWALL:INVA_S

DNA sequence :
ATGAATAAAATTACCGGACTATTGTTAAATATTCGCAATCGTCCTGAACTGTTGGTATTAGTCATCATGGTCATGGTTAT
TGCCATGCTGATTATACCTTTGCCGACGATTTTAGTAGATCTGTTAATTGGCCTGAATATTATGATTTCAGTGCTGATTT
TTATGGGATCATTTTATATTACACGGGTGTTGGACTTCCGGTCATTTCCCTCAATTTTATTGATTACTACGCTATTCCGA
TTAGCGTTATCGATCAGTACCAGCCGTCTTATTTTGCTGGAAGCTGATGCTGGCGACATTATTGCCACCTTTGGCGAGTT
TGTTATTCAGGACAATCTGGTGGTTGGGATGGTGGTATTTGCCATCGTGACCATTGTGCAGTTTATCGTGATTACCAAAG
GTTCTGAACGTATTGCCGAAGTTGCGGCGCGTTTCTCACTTGATGCGATGCCAGGTAAACAGATGAGCATTGACGCTGAT
TTGCGTGCTGGGGTGATTGATGAGGCAACAGTAAAAGAGAAACGTAATGATATGGAGAACGAGAGCCAGTTATACGGCTC
TTTTGATGGGGCGATGAAATTCATCAAAGGTGATGCTATCGCTGGGATCATCATTATTTTTGTCAATCTGATTGGTGGTA
TTTCCGTCGGAATGGCGCAATTGGGTATGGACATGCCTACGGCACTGAATACCTTCACCCTGCTGACCATTGGTGATGGC
TTGGTAGCACAAATTCCGGCTCTGCTTATCTCTATCAGTGCCGGCTTTATTGTGACTCGCGTGGGCGGCAATGATAAAAA
CCTTGGTGAAAATATTGTCTCTGAGCTGTTTGCCAAAGATTTCACTATTATGATCACCGCGATCATTGTTTGTAGCATTG
GTTTTCTGCCCGGGTTTCCTACGCCAATTTTCCTGTTCTTATCCGGTTTAATGGTAGCGCTGCTGTGGTATCGCCATCAT
CAGAAGCGCAAGGAGAAGAAACACCTTGCGGGTGATGAACAGAGTGATGCTGAAGTTAGCTCCGAGGTGGCAGAAGGCGA
AACTCGACGGGAAAGTCAGGTTTCAGATGATGAGTATGTACCTGAAACACTGCCAATTATTATTTCGGTGAGCCAAAAAC
ATAAGGAACTGCTGGAAGAAAATAGTTTTCTATCACGCATCAAGAAAGATATTTTTGTGCGCTATGGCTACCGCATCCCT
GATATTGCCATTAACTATTCTCCGGTGGTACCAAGCGACAAAATTATTGTGCTGATTAATGAAGTTCGTGCGGGTGATTA
TAATATTTGCTTTGGTGGTTTACGTCTTCTTACGATTAACGATGAACTGGAATATCTGGGGCTGGAATTAACCCGATTTA
CTGATGAGCATGGTGCAGTCAGTACCTGGATCGCCAGTAAACATACTGATGATATTAAACAACTGGGTTTAATGGCACGC
GATGATATTAGTGAGATTATCGACTGTATCGGAACTTTATTGCTGCATCACATTAATGAGTTCTTTGGGATTCAGGAAAC
TAAAAACCTGCTTGACGATCTGGAAAAGAAATACCCTGAATTATTAAAAGAGTGCTATCGCCATGCAACAGTACAAAAGA
TAACTGAAGTATTTCAGCGTCTGCTGATGGAAAAGATTTCCATCCGAAATATGAAACTTATTTTGGAAACTTTGGTGCAA
TGGGTGCCAAAAGAGAAAGACAGCATGATGCTGGTGGAATATGTCCGTGGCGCGATGGCCCGTTATATCTCATCTCGTTT
TGCCACCGATGGGCGTTTGAATGTTCTGATGATTAATGATCAATTTGAAGACATGATTCGCCAAGGGATTCGTCAGGCCT
CCGGCGGTAGCTTTATCAGCCTTGATCCGGCAAAAACCGATGACATTATTCAGGCCTTTGCTCAGACAGTAGAAAGCAGT
TATCACTCCGTTCGAGATATGAGTGTGCTGGTGCCCGTAGATATTCGTCGTTTTGTGAAAAAAATTCTTGAGAGTCGTTT
CCCTGAATTGGAGGTGCTCTCATTTAATGAGATCTCCGAGACAGTGAAAGTGAACGTAATTAAAACCGTGTAA

Protein sequence :
MNKITGLLLNIRNRPELLVLVIMVMVIAMLIIPLPTILVDLLIGLNIMISVLIFMGSFYITRVLDFRSFPSILLITTLFR
LALSISTSRLILLEADAGDIIATFGEFVIQDNLVVGMVVFAIVTIVQFIVITKGSERIAEVAARFSLDAMPGKQMSIDAD
LRAGVIDEATVKEKRNDMENESQLYGSFDGAMKFIKGDAIAGIIIIFVNLIGGISVGMAQLGMDMPTALNTFTLLTIGDG
LVAQIPALLISISAGFIVTRVGGNDKNLGENIVSELFAKDFTIMITAIIVCSIGFLPGFPTPIFLFLSGLMVALLWYRHH
QKRKEKKHLAGDEQSDAEVSSEVAEGETRRESQVSDDEYVPETLPIIISVSQKHKELLEENSFLSRIKKDIFVRYGYRIP
DIAINYSPVVPSDKIIVLINEVRAGDYNICFGGLRLLTINDELEYLGLELTRFTDEHGAVSTWIASKHTDDIKQLGLMAR
DDISEIIDCIGTLLLHHINEFFGIQETKNLLDDLEKKYPELLKECYRHATVQKITEVFQRLLMEKISIRNMKLILETLVQ
WVPKEKDSMMLVEYVRGAMARYISSRFATDGRLNVLMINDQFEDMIRQGIRQASGGSFISLDPAKTDDIIQAFAQTVESS
YHSVRDMSVLVPVDIRRFVKKILESRFPELEVLSFNEISETVKVNVIKTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 3e-174 57
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 8e-168 54
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 8e-168 54
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 8e-168 54
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 8e-168 54
invA AAS66860.1 InvA Not tested SSR-2 Protein 8e-148 51
ECs3731 NP_311758.1 EivA Not tested LIM Protein 5e-153 51
lssD AAO18050.1 LssD Virulence TTSS locus Protein 7e-113 42
unnamed AAL06368.1 EscV Virulence LEE Protein 1e-103 41
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 2e-102 41
escV AAC38382.1 EscV Virulence LEE Protein 2e-102 41
escV CAC81861.1 EscV protein Virulence LEE II Protein 5e-103 41
escV YP_003223476.1 translocator EscV Virulence LEE Protein 4e-103 41
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 3e-103 41
escV CAI43875.1 EscV protein Virulence LEE Protein 3e-103 41
escV AAK26714.1 EscV Virulence LEE Protein 2e-103 41
escV AAL57541.1 EscV Virulence LEE Protein 2e-103 41
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 4e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ysaV YP_001007704.1 type III secretion system apparatus protein VFG1780 Protein 0.0 100
ysaV YP_001007704.1 type III secretion system apparatus protein VFG2461 Protein 1e-164 54
ysaV YP_001007704.1 type III secretion system apparatus protein VFG0557 Protein 4e-168 54
ysaV YP_001007704.1 type III secretion system apparatus protein VFG1006 Protein 5e-156 52
ysaV YP_001007704.1 type III secretion system apparatus protein VFG0729 Protein 1e-102 41
ysaV YP_001007704.1 type III secretion system apparatus protein VFG0064 Protein 3e-114 41
ysaV YP_001007704.1 type III secretion system apparatus protein VFG0198 Protein 3e-107 41
ysaV YP_001007704.1 type III secretion system apparatus protein VFG0384 Protein 3e-111 41