Gene Information

Name : lysS (YE3374)
Accession : YP_001007545.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 3686176 - 3687693 bp
Length : 1518 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCAGAGCAAAAACCACAAGTCGCTGAGCAAGCGCAAGAACTCAATAGTGAGTTACAAGCTCGTCGGGAAAAACTGGC
AGCACTGCGGGAAAAAGGGATTGCTTTCCCTAATGATTTCCGTCGTGAGCACCTCTCAGACCAGCTACATGCCGAGTACG
GCGAAAAAACAAATGAAGAATTAGAAGCGCTGGATATCGAAGTGACTGTTGCTGGCCGTATGATGACTCGCCGTATTATG
GGTAAAGCATCATTTGTGACGCTGCAAGATGTCGGTGGCCGTATCCAGCTATACGTTTCCCGCGATGACCTGCCGGAAGG
CGTTTATAACGAAGAATTTAAAAAGTGGGATCTCGGCGATATCTTGGGTGCACGCGGCAAGTTGTTCAAAACTAAAACTG
GCGAGCTGTCTATCCACTGTAGTGAGTTGCGTTTACTGACCAAAGCATTGCGCCCGCTGCCGGATAAATTCCACGGTCTG
GCTGATCAGGAAACCCGCTATCGTCAGCGTTATCTGGATCTAATCGCTAACGACGAATCCCGCAATACATTCAAAGTTCG
TTCGCAAGTGATGTCAGGTATTCGCCGCTTCATGGTGGAAAAAGGCTTCATGGAAGTCGAAACTCCTATGATGCAAGTGA
TTCCCGGAGGTGCTTCAGCGCGCCCATTCGTGACTCATCACAATGCGCTGGATATCGATATGTACTTGCGTATCGCCCCA
GAGTTGTATCTGAAGCGCTTGGTAGTCGGTGGTTTTGAACGAGTGTTCGAAATCAACCGTAACTTCCGTAATGAAGGTGT
TTCACCGCGTCATAACCCAGAGTTCACCATGATGGAACTCTATATGGCTTATGCGGATTACAAAGACCTGATAGCGTTGA
CCGAAGAGTTATTCCGGACACTGACTGAAACCGTGCTGGGTAGCAGTGTGGTGCAGTATGGTGACCAGACCTTCGATTTT
GGTAAGCCTTTTGCCAAATTGACCATGAAAGAAGCTATTTGCAAATATCGTCCAGAAACCAATGTGGCTGATTTGGACGA
TATGGATAAAGCAGTAGCTATCGCTGAGTCCTTGGGTATTAAAGTTGAGAAGAGCTGGGGCTTGGGCCGCGTTCAATGCG
AAATTTTTGAAGAGACGGCAGAGAGCCACCTGATTCAACCTACCTTCATCACTGAATACCCAGCAGAAGTTTCACCGTTG
GCACGTCGTAATGATGATAATCCGTTTATCACTGACCGCTTCGAATTCTTCATCGGTGGCCGTGAAATTGGTAATGGTTT
CTCCGAGCTGAATGATGCTGAAGATCAGGCACAGCGCTTTGCTGATCAGGTTAGCGCCAAAGAAGCTGGTGATGATGAAG
CGATGTTCTACGACGAAGACTATGTTACTGCACTGGAACATGGCTTGCCGCCGACCGCGGGTCTGGGTATCGGTATCGAC
CGTATGGTGATGTTGTTTACCAACAGCCACACCATCCGCGATGTTATCTTGTTCCCAGCGATGCGCCCGGTAAAATAA

Protein sequence :
MSEQKPQVAEQAQELNSELQARREKLAALREKGIAFPNDFRREHLSDQLHAEYGEKTNEELEALDIEVTVAGRMMTRRIM
GKASFVTLQDVGGRIQLYVSRDDLPEGVYNEEFKKWDLGDILGARGKLFKTKTGELSIHCSELRLLTKALRPLPDKFHGL
ADQETRYRQRYLDLIANDESRNTFKVRSQVMSGIRRFMVEKGFMEVETPMMQVIPGGASARPFVTHHNALDIDMYLRIAP
ELYLKRLVVGGFERVFEINRNFRNEGVSPRHNPEFTMMELYMAYADYKDLIALTEELFRTLTETVLGSSVVQYGDQTFDF
GKPFAKLTMKEAICKYRPETNVADLDDMDKAVAIAESLGIKVEKSWGLGRVQCEIFEETAESHLIQPTFITEYPAEVSPL
ARRNDDNPFITDRFEFFIGGREIGNGFSELNDAEDQAQRFADQVSAKEAGDDEAMFYDEDYVTALEHGLPPTAGLGIGID
RMVMLFTNSHTIRDVILFPAMRPVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-167 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001007545.1 lysyl-tRNA synthetase VFG1668 Protein 1e-167 69