Gene Information

Name : thyA (YE3317)
Accession : YP_001007490.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3625196 - 3625990 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCTGGATTTGATGAAAAAAGTGCTGGAAGAAGGCACTACTAAAGATGACCGCACCGGTACTGGGACGCT
GTCGATTTTTGGGCATCAGATGCGTTTCAATTTACAAGATGGTTTCCCGCTGGTAACCACCAAGCGCTGCCATTTGCGTT
CCATCATTCATGAGTTGTTATGGTTCCTCAATGGCGATACCAATATTGGTTATCTGAAGGAAAATAACGTCTCAATCTGG
GATGAGTGGGCCGATGAAAACGGTGATCTTGGCCCGGTTTATGGTAAGCAATGGCGCGCTTGGGGCGCTGCTGATGGCCG
CCAGATTGACCAACTGAGTAAGGTAGTGCAACAGCTTAAGCAAGACCCAAACTCCCGTCGTATCATCGTTTCTGCATGGA
ATGTGGGTGAGTTGGATCAAATGGCTTTGGCACCGTGCCATGCTTTCTTCCAGTTTTATGTGGCTGATGGCAAGCTATCT
TGTCAGCTATATCAACGCTCTTGCGATGTGTTCCTCGGCTTACCATTTAACATTGCCAGCTATGCATTACTGGTACATAT
GATGGCGCAGCAATGTGATTTGGCAGTGGGTGATTTTGTTTGGACGGGGGGCGATACGCACTTATACAGCAACCATATTG
AGCAAACTCACCTGCAATTAAGCCGTGAACCGCGGGCGCTGCCAAAACTAATTATCAAAAGTAAACCTGCTTCATTGTTT
GACTATCGTTTCGAAGATTTTGAAATTGAAGGGTATGACCCTCACCCTGGCATCAAAGCCCCGATTGCTATCTGA

Protein sequence :
MKQYLDLMKKVLEEGTTKDDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLNGDTNIGYLKENNVSIW
DEWADENGDLGPVYGKQWRAWGAADGRQIDQLSKVVQQLKQDPNSRRIIVSAWNVGELDQMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLAVGDFVWTGGDTHLYSNHIEQTHLQLSREPRALPKLIIKSKPASLF
DYRFEDFEIEGYDPHPGIKAPIAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-80 64