Gene Information

Name : leuS (YE2996)
Accession : YP_001007185.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3266354 - 3268936 bp
Length : 2583 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATACCGCCCAGAAGATATCGAAACGCAAGTACAGCTTCACTGGCAAGAGAAGCAAACTTTTAAAGTCAC
TGAAGATACCAGCAAAGAAAAATATTACTGCCTATCCATGCTGCCGTATCCGTCAGGACGCCTACATATGGGGCACGTTC
GTAACTACACCATTGGTGATGTTATCTCCCGTTACCAGCGCATGCTGGGCAAAAACGTGTTACAGCCGATCGGCTGGGAT
GCATTTGGTCTGCCAGCTGAAGGCGCTGCGGTAAAAAACAACACCGCACCGGCCCCCTGGACTTACGACAACATTGAATA
CATGAAGAACCAGTTAAAATTACTGGGCTTCGGCTATGACTGGGATCGCGAGATTGCCACCTGCTCACCCGATTACTACC
GTTGGGAACAGTGGTTCTTCACCAAATTGTATGAAAAAGGCATGGTCTACAAAAAGACCTCAGCCGTTAACTGGTGTCCA
CACGACCTGACCGTTTTAGCTAACGAGCAGGTTATCGACGGCTGCTGCTGGCGTTGTGATACCAAAGTTGAACGTAAAGA
AATCCCACAGTGGTTTATTAAAATTACTGATTACGCTGATCAATTGCTTAATGATCTGGACACGCTGGAAAGCTGGCCAG
AACAAGTTAAGACCATGCAACGTAACTGGATTGGCCGCTCTGAAGGGGTTGATATCGTTTTCAACGTCGCAGATAGCGAA
GAGAAGCTCTCCGTTTACACCACGCGCCCGGACACCTTTATGGGTGTGACTTACGTAGCTGTTGCTGCTGGTCATCCGCT
GTCATTACAAGCCGCAGCGACTAACCCTGCACTGGCTGATTTTGTCGCGGAATGCCGGAACACCAAGGTTGCCGAAGCTG
AAATGGCCACTATGGAGAAAAAAGGCATGGCTACCGGCCTGTATGCCATCCATCCACTGACAGGTGAAAAATTACCTATC
TGGGCGGCTAACTTTGTCTTGATGGATTACGGCACCGGTGCGGTAATGGCGGTTCCGGGCCACGATGCCCGCGACTGGGA
ATTTGCGACTAAATATAATTTACCAATCAAACCGGTTATTTTGGCTGCTGATGGCAGTGAGCCAGACTTGAGCCAGGAAG
CCATGACCGAGAAAGGCATACTGTTCAACTCCGGTGAGTTTGATGGTCTGAATTATGAAGATGGCTTCAATGCGGTTGCC
GACAAACTGGTCGCCCTCGGTGTCGGTCAGCGCAAAGTCAACTATCGCCTGCGTGACTGGGGTGTTTCCCGTCAGCGTTA
TTGGGGGGCGCCTATCCCGATGGTGACACTGGAAGACGGCACCGTGGTACCAACTCCAGAAGATCAACTGCCGGTTATCC
TGCCGGAAGATGTGGTGATGGATGGTATTACCAGCCCAATAAAGGCCGATCCTGAGTGGGCTAAAACCACCGTTAATGGC
GTGCCGGGCCTGCGTGAAACTGATACCTTTGATACCTTTATGGAATCATCATGGTATTACGCGCGCTACACCTGCCCACA
ATTTGATAAAGGCATGCTGGATCCAGCCGCCGCCAACTATTGGCTGCCGGTTGATCAATATGTCGGTGGTATTGAACATG
CCATCATGCACTTGATGTACTTCCGCTTTTTCCACAAATTGCTGCGTGACGCAGGTTTAGTTGACTCCGATGAGCCAGCC
AAGCGCCTGCTGTGTCAGGGTATGGTTCTGGCAGATGCCTTCTATTACAGCGGCTCCAACGGTGAGCGTATCTGGGTTTC
ACCGGTGGACGCCATTGTTGAGCGTGATGATAAAGGGCGCATCATTAAAGCGACTGATGCCGAAGGCCATGAACTGGTTT
ACGCTGGCATGAGCAAAATGTCGAAATCGAAAAATAACGGTATCGACCCACAAGTCATGGTAGAAAAATACGGTGCCGAT
ACCGTGCGCCTGTTTATGATGTTTGCCTCACCAGCAGAAATGACGCTGGAATGGCAGGAATCTGGTGTCGAAGGAGCTAA
CCGCTTCCTGAAACGCGTCTGGCGTCTGGCCTATGATCACACCGCCAAAGGGGCAACCGCACCACTGGATGTTGCCAACC
TGACGGAAGAGCAGAAATCCTTACGCCGCGACCTGCATAAAACTATTGCCAAAGTCACTGATGACGTGGGCCGCCGTCAA
ACTTTCAATACCGCGATTGCTGCGGTGATGGAGTTGATGAACAAGCTGGGTCGCGCACCTCAGGAAACCGAGCAAGACCG
TGCTCTGCTGCAAGAAGCATTATTGGCAGTGGTTCGGATGCTTTATCCATTCACACCTCACGTTTGCTTTAGCTTGTGGC
AAGCTCTGGGTGGCGAAGGTGATATTGATACCGCACCATGGCCAGTTGCTGATGAACAAGCGATGGTCGAAGACTCTAAA
TTAGTGGTCGTACAGGTTAATGGTAAAGTGCGTGGCCGCATTACTGTGCCAGCCGATGCCACTGAACAGCAAGTGCGTGA
ACGTGCTGGTCAGGAACACTTGGTGGCTAAATACCTGGATGGAGTTACCGTACGTAAAGTCATCTATGTCCCTGGCAAAC
TGCTTAACCTGGTTGTGGGTTAA

Protein sequence :
MQEQYRPEDIETQVQLHWQEKQTFKVTEDTSKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDREIATCSPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCP
HDLTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFNVADSE
EKLSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMATMEKKGMATGLYAIHPLTGEKLPI
WAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKPVILAADGSEPDLSQEAMTEKGILFNSGEFDGLNYEDGFNAVA
DKLVALGVGQRKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
VPGLRETDTFDTFMESSWYYARYTCPQFDKGMLDPAAANYWLPVDQYVGGIEHAIMHLMYFRFFHKLLRDAGLVDSDEPA
KRLLCQGMVLADAFYYSGSNGERIWVSPVDAIVERDDKGRIIKATDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGANRFLKRVWRLAYDHTAKGATAPLDVANLTEEQKSLRRDLHKTIAKVTDDVGRRQ
TFNTAIAAVMELMNKLGRAPQETEQDRALLQEALLAVVRMLYPFTPHVCFSLWQALGGEGDIDTAPWPVADEQAMVEDSK
LVVVQVNGKVRGRITVPADATEQQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-158 43