Gene Information

Name : irp2 (YE2617)
Accession : YP_001006815.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Virulence
Product : yersiniabactin biosynthetic protein
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1020
EC number : -
Position : 2820259 - 2826366 bp
Length : 6108 bp
Strand : +
Note : -

DNA sequence :
ATGATTTCTGGCGCACCATCTAAGGATTCGCTGTTACCGGACAACCGCCACGCGGCTGATTACCAACAATTACGCGAGCG
GCTTATACAGGAACTGAATTTAACGCCGCAGCAGTTACATGACGAAAGCAACCTGATCCAGGCCGGCCTGGATTCAATAA
GATTGATGAGATGGTTACACTGGTTTCGTAAAAATGGCTACCGCCTTACCCTTCGCGAGCTGTATGCCGCCCCCACGCTG
GCGGCATGGAACCAGTTAATGCTCAGCCGGTCGCCGGAGAACGCGGAAGAAGAAACGCTGCCCGACGAATCATCCTGGCC
GAACATGACCGAAAGTACCCCCTTCCCATTGACGCCGGTACAGCACGCCTACCTGACGGGCCGCATGCCGGGGCAGACGC
TTGGCGGCGTGGGTTGCCACCTGTATCAGGAGTTTGAAGGCCATTGTCTGACGGCGTCGCAACTGGAGCAGGCCATCACG
ACCTTGCTGCAACGCCACCCAATGCTGCATATCGCCTTTCGCCCCGACGGGCAGCAGGTCTGGCTACCGCAACCTTACTG
GAACGGCGTCACCGTTCATGATTTACGCCATAACGACGCTGAAAGCCGCCAGGCCTATCTGGACGCACTGCGCCAGCGCC
TCAGCCACCGTCTTTTACGCGTGGAGATCGGCGAAACATTTGATTTTCAGCTGACGCTCTTGCCGGACAATCGCCACCGC
CTCCATGTCAATATTGACCTGCTGATTATGGATGCCTCCAGCTTTACGCTTTTCTTCGATGAGCTTAACGCCCTGCTGGC
CGGAGAATCGCTGTCGGCTATCGACACCCGCTATGATTTCCGCTCGTATTTGCTGCACCAGCAGAAGATCAATCAACCAC
TGAGAGACGACGCACGCGCTTACTGGCTGGCGAAAGCATCGACGCTTCCCCCCGCGCCCGTCTTGCCGCTGGTCTGCGAA
CCCGCCACGCTACGTGAAGTCCGTAATACCCGGCGCCGCATGATTGTCCCAGCAACACGCTGGCACGCCTTTAGCAACCG
GGCCGGCGAATATGGCGTGACGCCAACAATGGCGCTGGCGACCTGTTTTTCTGCCGTGCTGGCTCGCTGGGGCGGCCTGA
CGCGTCTGCTGCTTAACATCACCTTATTCGACCGCCAGCCGCTGCACCCAGCGGTTGGCGCGATGCTTGCCGACTTCACC
AATATTCTTCTGCTGGATACCGCCTGCGATGGCGATACCGTCAGCAACCTGGCGCGTAAAAACCAGCTCACGTTTACGGA
GGACTGGGAGCATCGCCACTGGTCCGGCGTCGAATTACTCCGTGAACTCAAACGCCAGCAGCGCTACCCCCACGGCGCCC
CGGTGGTATTTACCAGCAATCTGGGGCGTTCCCTCTACAGCAGCCGCGCAGAATCGCCGTTGGGCGAGCCGGAATGGGGC
ATCTCGCAAACGCCGCAGGTCTGGATAGATCATCTGGCGTTCGAGCATCACGGCGAGGTCTGGCTGCAATGGGACAGCAA
CGACGCGCTGTTCCCTCCGGCGTTAGTCGAAACATTGTTCGACGCCTACTGCCAGTTGATTAACCAACTCTGCGATGACG
AAAGCGCCTGGCAAAAGCCGTTCGCAGATATGATGCCCGCCAGCCAGCGCGCGATACGCGAACGGGTCAACGCCACCGGC
GCCCCCATTCCCGAAGGCTTGCTGCATGAAGGCATTTTCCGTATCGCTCTGCAACAGCCGCAGGCGCTGGCGGTAACGGA
CATGCGTTATCAGTGGAATTATCATGAGCTGACAGACTATGCCCGCCGTTGCGCAGGCAGGTTAGTCGAGTGCGGGGTTC
AGCCCGGCGATAATGTGGCTATCACGATGTCGAAAGGCGCAGGACAACTTGTTGCGGTTCTGGCCGTCCTGCTGGCCGGG
GCAGTTTACGTTCCGGTTTCGTTGGACCAGCCTGCCGCACGGCGCGAGAAAATCTACGCTGACGCCAGCGTCCGGCTGGT
GCTCATTTGCCAGCACGACGCCAGCGCCGGGTCAGACGATATTCCCGTCCTTGCCTGGCAGCAGGCCATTGAGGCGGAGC
CGATCGTCAACCCGGTGGTACGCGCCCCCACGCAACCGGCCTACATTATCTACACTTCCGGCTCTACCGGCACGCCGAAA
GGGGTAGTCATTTCTCACCGGGGAGCGCTCAACACCTGTTGCGATATCAATACCCGCTATCAGGTTGGCCCGCATGACAG
GGTGCTGGCCCTCTCCGCCCTGCATTTTGATTTATCGGTTTACGACATTTTTGGCGTACTGCGTGCGGGCGGCGCGCTGG
TGATGGTGATGGAAAATCAACGGCGCGATCCTCACGCATGGTGTGAGCTGATCCAGCGCCATCAGGTCACGCTCTGGAAC
AGCGTCCCGGCGCTGTTCGATATGCTGCTGACCTGGTGTGAAGGTTTCGCCGACGCCACGCCGGAAAACCTGCGCGCAGT
GATGCTTTCCGGCGACTGGATCGGACTTGACCTCCCCGCCCGTTATCGGGCCTTCCGGCCACAAGGACAATTTATCGCGA
TGGGCGGCGCCACCGAGGCGTCTATCTGGTCTAACGCCTGCGAAATTCACGACGTCCCTGCCCACTGGCGTTCCATCCCT
TACGGTTTTCCGCTAACCAACCAACGCTACCGGGTGGTGGATGAACGGGGCCGGGACTGCCCTGACTGGGTGTCGGGTGA
ATTATGGATTGGCGGCATCGGGGTCGCGGAAGGCTATTTCAACGATTCCCTGCGCAGCGAGCAGCAATTTTTGACGCTCC
CGGACGAGCGCTGGTATCGCACCGGCGATCTCGGCTGCTACTGGCCAGACGGCACAATCGAGTTCCTCGGTCGTCGCGAC
AAGCAGGTCAAAGTCGGAGGATATCGCATCGAGCTGGGCGAAATCGAAAGCGCGCTCAGCCAGTTGGCGGGGGTGAAACA
AGCAACCGTTCTGGCGATCGGCGAAAAAGAAAAAACGCTGGCGGCATACGTGGTTCCTCAGAGCGAGGCTTTTTGCGTTA
CCGATCATCGGAACCCGGCATTGCCGAAGGCGTGGCACACGCTTGCGGGAACGTTGCCCTGTTGCGCCATCTCGCCAGAG
ATCTCCGCAGAACAGGTAGCCGATTTCCTTCAGCATCGCCTGTTAAAACTGAAGCCGGGTCACACCGCTGGCGCCGATCC
TATCCCCCTGATGAATTCACTCGCTATCCAGCCGCGCTGGCAGGCCGTGGTGGAACGCTGGTTAGCATTTCTGGTGACGC
AACGGCGACTGAAGCCCGCTGCTGAAGGTTATCAGGTCTGCGCTGGTGAAGAACGCGAGGATGAGCACCCGCACTTCAGC
GGACATGATTTAACGTTATCGCAAATTCTTCGCGGTGCCCGTAACGAACTGTCGTTACTGAACGACGCGCAGTGGTCGCC
GGAAAGCCTGGCCTTTAACCATCCGGCCAGCGCCCCGTATATTCAGGAACTGGCGACAATTTGCCAACAGCTTGCACAGC
GCTTACAGCGCCCGGTACGCCTGCTTGAGGTGGGAACCCGCACCGGCCGCGCCGCAGAATCGCTGTTGGCACAGCTCAAC
GCCGGACAGATTGAGTATGTCGGGCTTGAGCAGAGCCAGGAGATGCTACTGAGCGCCCGGCAGAGGCTCGCCTCCTGGCC
TGGTGCCCGTCTGTCCCCCTGGAATGCAGACACGCTGGCGGCGCACGCTCACTCGGGGGACATTATCTGGCTTAATAACG
CCCTGCATCGTCTGCTGCCGGAAGATCCCGGGCTCCTTGCGACATTACAACAGCTTGCCGTTCCCGGCGCGCTGCTCTAC
GTGATGGAGTTTCGCCAGTTAACGCCGTCCGCCCTGCTCAGCACGCTCCTGTTAACCAATGGGCAGCCGGAGGCCTTGCT
GCATAACAGCGCCGACTGGGCGGCATTATTTAGCGCGGCCGCCTTCAACTGTCAGCATAGCGATGAGGTCGCGGGGTTAC
AACGCTTCCTCGTACAATGTCCTGACAGGCAGGTGCGCCGCGATCCCCGTCAACTTCAGGCCGCCCTCGCCGGGCGTCTG
CCGGGGTGGATGGTGCCGCAACGGATCGTCTTCCTCGACGCCTTACCGCTGACGGCTAACGGGAAAATTGACTACCAGGC
GCTGAAGCGTCGTCATACCCCTAAAGCGGAAAACCAGGCCGAAGCGGATTTACCCCAGGGCGACATTGAAAAACAGGTTG
CCGCCCTCTGGCAGCAACTCTTATCGACTGGCAATGTCACCAGAGAAACCGACTTCTTCCAGCAAGGCGGCGATAGCCTG
CTGGCGACCCGTCTGACCGGGCAACTTCATCAGGCAGGTTATGAAGCGCAATTAAGCGACCTGTTTAATCATCCCCGGCT
GGCGGATTTTGCCGCCACGCTGCGTAAAATCGACGTCCCGGTCGAACAACCATTCGTCCACTCTCCTGAAGAACGCTACC
AGCCCTTTGCGCTTACCGACGTGCAGCAGGCTTACCTGGTGGGGCGTCAGCCGGGCTTTACCCTGGGCGGCGTCGGCTCA
CATTTCTTTGTTGAATTTGAAATTGCCGATCTGGACCTCACCCGGCTGGAGACGGTCTGGAACCGATTAATCGCCCGCCA
CGATATGCTACGCGCCGTCGTGCTTGATGGACAGCAACAGGTGCTCGAACAGACGCCCCCCTGGGTGATACCCACACACA
CCCTTCATACGCCTGAAGAGGCGTTGCGGGTACGCGAAAAACTGGCGCATCAGGTACTCAACCCCGAAGTGTGGCCGGTA
TTCGATCTCCAGGTCGGATACGTGGACGGGATGCCCGCCCGCCTGTGGCTGTGTCTGGATAACCTGTTGCTTGACGGCCT
GAGCATGCAGATCCTGCTGGCGGAGCTGGAGCACGGCTACCGCTACCCGCAACAGCTGCTTCCGCCGCTGCCCGTCACCT
TCAGGGATTATCTGCAACAGCCCTCGCTACAGTCGCCCAATCCAGATTCTCTGGCATGGTGGCAGGCGCAGCTTGATGAT
ATTCCTCCGGCGCCAGCGTTGCCGCTGCGCTGCTTGCCTCAGGAGGTTGAAACACCGCGCTTCGCCCGCCTGAACGGCGC
GCTGGACAGCACGCGCTGGCATCGGCTGAAAAAACGGGCGGCTGACGCCCATCTCACCCCGTCGGCCGTGCTGTTGTCGG
TGTGGTCAACGGTTCTCTCTGCATGGAGTGCGCAGCCTGAGTTCACGCTTAACCTTACGCTTTTCGACAGGCGACCGCTG
CACCCGCAAATCAACCAGATTCTGGGCGATTTCACTTCGCTGATGTTGCTGAGCTGGCACCCCGGCGAAAGCTGGCTGCA
CAGCGCGCAGTCACTACAGCAGCGGCTGAGCCAGAACCTCAACCACCGCGATGTGTCAGCCATCCGCGTGATGCGTCAAC
TGGCGCAACGGCAAAACGTGCCTGCCGTTCCGATGCCCGTCGTCTTTACCAGCGCGCTGGGCTTTGAGCAGGATAACTTC
CTCGCCCGGCGTAATCTGCTCAAGCCGGTCTGGGGCATCTCCCAGACGCCGCAGGTCTGGCTCGATCACCAGGTTTATGA
ATCCGAAGGCGAACTGCGCTTTAACTGGGATTTTGTCGCCGCGCTGTTTCCTGCCGGGCAGGTGGAGCGCCAGTTTGAAC
AGTATTGCGCATTGCTAAACCGAATGGCCGAGGATGAAAGCAGCTGGCAACTGCCGCTCGCCGCGCTGGTGCCTCCCGTA
AAACACGCAGGGCAATGCGCAGAGCGCCCACCGCGCGTATGCCCTGAGCACTCTCAGCCACACATTGCGGCGGACGAGAG
CACCGTCAGCCTGATTTGCGACGCCTTCCGCGAGGTGGTTGGCGAGTCTGTCACACCCGCAGAAAACTTCTTTGAGGCGG
GTGCAACATCGCTGAATCTGGTGCAACTGCACGTTTTGTTACAACGTCACGAATTTTCCACCCTGACGTTGCTTGACCTC
TTCACCCACCCTTCTCCTGTTGCCCTGGCCGATTATCTGGCCGGCGTCGCCACGGTGGAGAAAACAAAACGTCCTCGCCC
TGTTCGCCGTCGTCAGCGGCGGATATAG

Protein sequence :
MISGAPSKDSLLPDNRHAADYQQLRERLIQELNLTPQQLHDESNLIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTL
AAWNQLMLSRSPENAEEETLPDESSWPNMTESTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFEGHCLTASQLEQAIT
TLLQRHPMLHIAFRPDGQQVWLPQPYWNGVTVHDLRHNDAESRQAYLDALRQRLSHRLLRVEIGETFDFQLTLLPDNRHR
LHVNIDLLIMDASSFTLFFDELNALLAGESLSAIDTRYDFRSYLLHQQKINQPLRDDARAYWLAKASTLPPAPVLPLVCE
PATLREVRNTRRRMIVPATRWHAFSNRAGEYGVTPTMALATCFSAVLARWGGLTRLLLNITLFDRQPLHPAVGAMLADFT
NILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQRYPHGAPVVFTSNLGRSLYSSRAESPLGEPEWG
ISQTPQVWIDHLAFEHHGEVWLQWDSNDALFPPALVETLFDAYCQLINQLCDDESAWQKPFADMMPASQRAIRERVNATG
APIPEGLLHEGIFRIALQQPQALAVTDMRYQWNYHELTDYARRCAGRLVECGVQPGDNVAITMSKGAGQLVAVLAVLLAG
AVYVPVSLDQPAARREKIYADASVRLVLICQHDASAGSDDIPVLAWQQAIEAEPIVNPVVRAPTQPAYIIYTSGSTGTPK
GVVISHRGALNTCCDINTRYQVGPHDRVLALSALHFDLSVYDIFGVLRAGGALVMVMENQRRDPHAWCELIQRHQVTLWN
SVPALFDMLLTWCEGFADATPENLRAVMLSGDWIGLDLPARYRAFRPQGQFIAMGGATEASIWSNACEIHDVPAHWRSIP
YGFPLTNQRYRVVDERGRDCPDWVSGELWIGGIGVAEGYFNDSLRSEQQFLTLPDERWYRTGDLGCYWPDGTIEFLGRRD
KQVKVGGYRIELGEIESALSQLAGVKQATVLAIGEKEKTLAAYVVPQSEAFCVTDHRNPALPKAWHTLAGTLPCCAISPE
ISAEQVADFLQHRLLKLKPGHTAGADPIPLMNSLAIQPRWQAVVERWLAFLVTQRRLKPAAEGYQVCAGEEREDEHPHFS
GHDLTLSQILRGARNELSLLNDAQWSPESLAFNHPASAPYIQELATICQQLAQRLQRPVRLLEVGTRTGRAAESLLAQLN
AGQIEYVGLEQSQEMLLSARQRLASWPGARLSPWNADTLAAHAHSGDIIWLNNALHRLLPEDPGLLATLQQLAVPGALLY
VMEFRQLTPSALLSTLLLTNGQPEALLHNSADWAALFSAAAFNCQHSDEVAGLQRFLVQCPDRQVRRDPRQLQAALAGRL
PGWMVPQRIVFLDALPLTANGKIDYQALKRRHTPKAENQAEADLPQGDIEKQVAALWQQLLSTGNVTRETDFFQQGGDSL
LATRLTGQLHQAGYEAQLSDLFNHPRLADFAATLRKIDVPVEQPFVHSPEERYQPFALTDVQQAYLVGRQPGFTLGGVGS
HFFVEFEIADLDLTRLETVWNRLIARHDMLRAVVLDGQQQVLEQTPPWVIPTHTLHTPEEALRVREKLAHQVLNPEVWPV
FDLQVGYVDGMPARLWLCLDNLLLDGLSMQILLAELEHGYRYPQQLLPPLPVTFRDYLQQPSLQSPNPDSLAWWQAQLDD
IPPAPALPLRCLPQEVETPRFARLNGALDSTRWHRLKKRAADAHLTPSAVLLSVWSTVLSAWSAQPEFTLNLTLFDRRPL
HPQINQILGDFTSLMLLSWHPGESWLHSAQSLQQRLSQNLNHRDVSAIRVMRQLAQRQNVPAVPMPVVFTSALGFEQDNF
LARRNLLKPVWGISQTPQVWLDHQVYESEGELRFNWDFVAALFPAGQVERQFEQYCALLNRMAEDESSWQLPLAALVPPV
KHAGQCAERPPRVCPEHSQPHIAADESTVSLICDAFREVVGESVTPAENFFEAGATSLNLVQLHVLLQRHEFSTLTLLDL
FTHPSPVALADYLAGVATVEKTKRPRPVRRRQRRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp2 YP_001006815.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 100
irp2 YP_002346902.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 99
irp2 NP_669706.1 HMWP2 nonribosomal peptide synthetase Virulence HPI Protein 0.0 99
irp2 YP_070124.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 99
irp2 YP_853075.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 0.0 99
irp2 NP_993007.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 99
irp2 CAA21390.1 - Virulence HPI Protein 0.0 99
PMI2599 YP_002152317.1 non-ribosomal peptide synthase Not tested Not named Protein 0.0 41