Gene Information

Name : fliI (YE2540)
Accession : YP_001006744.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2734554 - 2735885 bp
Length : 1332 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGGATAAATTCGAAGAACGTATTAGCCAATCAACTACCATTCGCCGTTACGGGCGATTAACGCGCGCCACCGGCCTGGT
GCTGGAAGCCACTGGCTTGCAACTGCCACTGGGGGCCACCTGTCTGATTGAGCGCCATGATAACGGCGAAGTACAAGAAG
TTGAGAGTGAAGTGGTCGGTTTTAACGGCCAGCGCCTGTTCCTGATGCCACTGGAAGAAGTGGAAGGGATTGTGCCCGGC
GCCCGGGTTTATGCACGCATCACCACCGGTGGAGCCTCGGCCAGTAAGCAATTGCCACTCGGCCCAGAATTACTCGGGCG
CGTATTAGATGGCAGCGCCAAGCCACTTGATGGCTTACCCGCCCCTGAAACCGGCTACCGCGCCCCGCTTATCACTCCCC
CGATCAACCCATTACAACGTACCGCGATTGAACAGGTATTGGATGTTGGTGTGCGCACCATTAATGCCCTGCTGACCGTC
GGTCGTGGGCAGCGTATGGGCCTGTTCGCTGGCTCTGGGGTGGGGAAAAGTGTGCTGTTAGGCATGATGGCTCGCTACAC
CCAAGCGGATGTTATTGTCGTTGGCTTGATCGGTGAACGTGGCCGTGAAGTAAAAGATTTTATTGAGAACATTTTAGGCC
CCGAAGGGCGTGCGCGCTCAGTAGTCATCGCCGCACCGGCTGATGTATCGCCGTTACTGCGCATGCAAGGGGCGGCTTAT
GCCACTCGTATTGCAGAAGATTTTCGTGACCGTGGTCAGCATGTCCTGCTGATTATGGACTCCCTGACGCGCTATGCCAT
GGCACAACGTGAAATCGCGCTGGCTATCGGCGAGCCTCCGGCGACCAAAGGTTATCCGCCGTCGGTATTCGCCAAATTAC
CGGCGCTGGTTGAGCGTGCTGGTAACGGGGTGTCCGGTGGTGGATCGATCACCGCTTTTTATACGGTATTGACCGAGGGC
GATGATCAGCAAGACCCGATCGCCGACTCTGCTCGCGCCATTCTTGATGGGCACGTGGTGCTATCGCGCCGCCTGGCGGA
ATCGGGCCACTACCCCGCTATTGATATTGAAGCCTCTATCAGCCGCGCCATGACCTCGCTGATAGATGAGAACCACTACA
GCAAAGTTCGCCAATTTAAACAATTGCTTGCAAGCTTCCAACGTAACCGTGATTTAGTCAGCGTAGGAGCCTATGCCGCC
GGAAGTGACCCATTATTGGATAAGGCTATTGCTTTGTATCCGCAAATGGAAATCTTCTTGCAGCAAGGCATGTTCGAACG
CAGCAGTTACGAAGATGCCTGCCAGCATCTGAAAAGCTTGTTTCCAGGTTGA

Protein sequence :
MDKFEERISQSTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHDNGEVQEVESEVVGFNGQRLFLMPLEEVEGIVPG
ARVYARITTGGASASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLITPPINPLQRTAIEQVLDVGVRTINALLTV
GRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENILGPEGRARSVVIAAPADVSPLLRMQGAAY
ATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEG
DDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDENHYSKVRQFKQLLASFQRNRDLVSVGAYAA
GSDPLLDKAIALYPQMEIFLQQGMFERSSYEDACQHLKSLFPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-80 53
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-82 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-81 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-81 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-79 47
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-79 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-81 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-81 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-81 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-74 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-65 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 4e-71 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 6e-71 45
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-70 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-71 45
escN AAC38383.1 EscN Virulence LEE Protein 1e-70 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 5e-71 45
escN AAC31513.1 L0034 Virulence LEE Protein 9e-71 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 9e-71 45
escN AAK26715.1 EscN Virulence LEE Protein 5e-71 45
escN AAL57542.1 EscN Virulence LEE Protein 5e-71 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-70 45
escN CAI43874.1 EscN protein Virulence LEE Protein 5e-71 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-70 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-73 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-73 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-66 43
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-67 43
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-67 43
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 9e-68 43
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-67 43
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-68 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-72 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-57 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-68 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-72 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-68 42
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-68 42
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-68 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 9e-68 41
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_001006744.1 flagellum-specific ATP synthase VFG2331 Protein 0.0 100
fliI YP_001006744.1 flagellum-specific ATP synthase VFG2499 Protein 2e-144 70
fliI YP_001006744.1 flagellum-specific ATP synthase VFG1254 Protein 3e-122 62
fliI YP_001006744.1 flagellum-specific ATP synthase VFG0048 Protein 4e-79 47
fliI YP_001006744.1 flagellum-specific ATP synthase VFG2144 Protein 2e-83 46
fliI YP_001006744.1 flagellum-specific ATP synthase VFG0192 Protein 2e-82 45
fliI YP_001006744.1 flagellum-specific ATP synthase VFG0730 Protein 8e-71 45
fliI YP_001006744.1 flagellum-specific ATP synthase VFG0812 Protein 5e-71 45
fliI YP_001006744.1 flagellum-specific ATP synthase VFG0390 Protein 5e-75 44
fliI YP_001006744.1 flagellum-specific ATP synthase VFG0515 Protein 5e-68 43