Gene Information

Name : hemC (YE0187)
Accession : YP_001004576.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 222463 - 223404 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAATTATTCGAATTGCCACGCGACAAAGCCCGCTCGCCTTATGGCAAGCACATTATGTTCAACATTTACT
GCAAGCCAATCACCCAGGCCTGCAAGTCGAATTGGTGCCAATGGTGACCCGTGGGGACATCATTCTGGACACGCCACTGG
CAAAGGTTGGTGGTAAAGGTTTGTTTGTTAAAGAATTAGAACTAGCGCTATTGGAAGGACGAGCAGATATTGCCGTTCAT
TCAATGAAAGATGTCCCGATTGCCTTCCCTGAAGGATTGGGTCTGGTCACCATTTGTGAGCGTGATGACCCTCGCGATGC
TTTCGTATCAATAAATTATGCTCATTTGGATGAGTTGCCCGCTGGCAGCATTGTGGGCACATCAAGCTTGCGCCGTCAGT
GTCAATTGCGTGAGCGCCGCCCTGATCTGATTATCCGTGACCTGCGCGGTAACGTCGGCACGCGTCTTGCCAAGTTAGAT
AAAGGTGAATACCACGCCATTATTTTAGCCGTTGCTGGCCTCAAGCGCCTCGGGCTGGAAACGCGAATTCGTTATGCCAT
GCCTGCTGAGGAGTCATTGCCTGCGGTCGGTCAAGGTGCTGTCGGTATTGAATGCCGTCTCGATGATAATTTTACCCGTC
AATTACTGGCACCATTGAATCATCGCGAGACTGAATTGCGCGTGTGCGCTGAACGCGCCATGAATACCCGCCTTGAAGGA
GGTTGCCAGGTGCCTATCGGCAGTTATGCCGAATTGGACGGCGATACACTGTGGCTTCGCGCATTGGTCGGTGCCCCTGA
TGGCAGTGAAATTATTCGCGGTGAACGCCGAGGGCCGGCTGAAAATGCAGAGCAAATGGGTGTTGAACTGGCCGATGAGC
TGCTATCACGGGGTGCCAGAGAGATACTGGCTGAGGTTTATCAGGATAATCCACCGCTATGA

Protein sequence :
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLEGRADIAVH
SMKDVPIAFPEGLGLVTICERDDPRDAFVSINYAHLDELPAGSIVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLD
KGEYHAIILAVAGLKRLGLETRIRYAMPAEESLPAVGQGAVGIECRLDDNFTRQLLAPLNHRETELRVCAERAMNTRLEG
GCQVPIGSYAELDGDTLWLRALVGAPDGSEIIRGERRGPAENAEQMGVELADELLSRGAREILAEVYQDNPPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-81 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-81 61