Gene Information

Name : cvrA; nhaP2; ycgO (YE1602)
Accession : YP_001005894.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1800852 - 1802579 bp
Length : 1728 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGACGCCATCACTATTAACAGCCTTTTTTTGATTGGCGCAGTGCTGGTGGGAGCCAGTATTTTACTGAGCTCACTCTC
TTCACGGTTAGGCATCCCCATTTTGGTCATCTTTCTGGCCATTGGTATGTTGGCAGGCACCGACGGCATCGGTGGGATTG
CCTTCGATAACTATCCTGTCGCGTATCTGGTCAGTAACCTGGCATTAGCCGTCATTCTGTTAGACGGCGGCATGCGTACC
CGAGCATCTTCCTTTCGTGTCGCATTGTGGCCTGCCCTGTCGCTGGCAACCGTAGGTGTGTTGATTACTGCGGGCCTGAC
CGGTTTGGCCGCCGCCTGGCTATTTGATTTAGATATCATTCAAGGCTTATTGATTGGTGCGATTATAGGTTCAACTGATG
CGGCAGCCGTTTTCTCACTGTTAGGTGGCAAAGGTCTCAACGAGCGAGTCAGTGCCACTCTGGAGATAGAATCAGGCAGT
AACGACCCAATGGCCGTATTCTTGACCATTACCCTGATTTCCATGATTTCCGCCGGTGAATCCAGCCTGAGCTGGATGTT
TTTGGTGCATCTGATTCAGCAATTTGGTTTGGGCATTATCATCGGATTGGGTGGCGGCAGCTTGCTGTTGTTGCTCATCA
ACCGGATAGAATTACCCAGCGGTTTATACCCATTACTGGCCGTCAGTGGCGGTATTTTGGTATTTTCACTCACCACCGCG
ATGAATGGCAGCGGGATTTTGGCGGTCTATCTCTGTGGCCTGATGCTCGGCAACCGCCCCATCCGCAACCGCGCGGGTAT
TTTACAGACCTTCGATGGGTTGGCATGGCTCAGTCAAATTGGCATGTTTCTGGTATTGGGGTTATTGCTTAACCCAAGTG
AGTTGTTGCCGATTGCCATTCCGGCATTAATTCTCTCATTGTGGATGATTCTATTCGCCCGACCACTATCAGTGTTTATC
GGCTTACTGCCCTTCCCCAGTTTTAATCTGCGTGAGCGCATCTTTATTTCATGGGTCGGTTTACGCGGTGCCGTTCCGGT
TATTCTGGCAGTATTCCCGATGATGGCCGGTATTCCCCATGCGAATTTATTCTTCAATGTCGCCTTTTTTGTCGTGCTGG
TCTCGCTGCTATTACAAGGCACCAGTTTGTCATTTGCTGCACGCAAAACAAAATTGGTGGTGCCGCCCGCGCTCGCTCCG
GTGGCACGGATTGGTTTAGACATTGATAAAAATAACCAGTGGGAGCAGTTTATTTACCAGCTCAGCTCCGATAAGTGGTG
TATCGGCGCAGCGCTGCGTGATTTAAAAATGCCGCAGGAAACGCGCATTGCGGCACTGTTTCGTGGCAAAGACTTATTAC
ATCCCAACGGCAATACCCGCTTGAAAGAAGGCGATATTTTGTGCGTTATTGGTCAGGAACATCACTTGCCCGCACTGGGA
AAATTATTTAGCCAGTCACCCAGCATCCAGTTGGATGAGCGCTTCTTTGGCGACTTTATTCTCGACGCAGATGCAAAGCT
TGATGATATATCTCAGATTTATGGTCTTAATCTGGAACAGGGTGTCGATAAACAACAAACACTCGGTCAGTTCGTGCTCT
ATCTCTTTGGTGGTGAACCGGTTATTGGTGACCAGATTGAGTGGGATGGCCTGACGTGGACCATTGCCGAAATGGAATCT
GACCGCGTGAGCCGGGTCGGGGTTAAAATAGTGACCGATAAAGCCTGA

Protein sequence :
MDAITINSLFLIGAVLVGASILLSSLSSRLGIPILVIFLAIGMLAGTDGIGGIAFDNYPVAYLVSNLALAVILLDGGMRT
RASSFRVALWPALSLATVGVLITAGLTGLAAAWLFDLDIIQGLLIGAIIGSTDAAAVFSLLGGKGLNERVSATLEIESGS
NDPMAVFLTITLISMISAGESSLSWMFLVHLIQQFGLGIIIGLGGGSLLLLLINRIELPSGLYPLLAVSGGILVFSLTTA
MNGSGILAVYLCGLMLGNRPIRNRAGILQTFDGLAWLSQIGMFLVLGLLLNPSELLPIAIPALILSLWMILFARPLSVFI
GLLPFPSFNLRERIFISWVGLRGAVPVILAVFPMMAGIPHANLFFNVAFFVVLVSLLLQGTSLSFAARKTKLVVPPALAP
VARIGLDIDKNNQWEQFIYQLSSDKWCIGAALRDLKMPQETRIAALFRGKDLLHPNGNTRLKEGDILCVIGQEHHLPALG
KLFSQSPSIQLDERFFGDFILDADAKLDDISQIYGLNLEQGVDKQQTLGQFVLYLFGGEPVIGDQIEWDGLTWTIAEMES
DRVSRVGVKIVTDKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 1e-146 76
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 1e-146 76