Gene Information

Name : kdsB (YE1550)
Accession : YP_001005844.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1739226 - 1739978 bp
Length : 753 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTCATTGCTATAATTCCCGCCCGTTATGCTTCAACCCGTCTACCAGGCAAGCCACTGGCGGATATCGCTGGCAA
ACCGATGGTAGTACATGTGATGGAGCGAGCGTTGGAGTCAGGTGCTTCCCAGGTGATTGTGGCAACAGACCATCCGGAAG
TGGTGACTGCGGTTGAAGCGGCGGGTGGCGAAGTGTGTCTAACCCGGGCTGATCATCAATCCGGTACCGAGCGCTTAGCG
GAAGTTATTGAGCGTTATGGCTTTGCCGATGATCAAATTATCGTCAATGTGCAAGGGGATGAGCCACTGGTGCCACCAGA
GATTATTCGCCAGGTTGCTGAGAATTTGGCAGCCTCCAGTGCGGGTATGGCAACATTGGCTGTGCCGATTGAAAGCAGTG
AAGAGGCCTTTAACCCTAATGCCGTGAAAGTGGTAATGGATGCACAAGGCTATGCGCTGTATTTCTCGCGCGCCGCTATT
CCGTGGGAAAGAGAGCGCTTTGCGCAGTCTAAAGAAACCATCGGCGATTGTTTCTTACGCCATATTGGCATTTATGCTTA
TCGCGCTGGTTTTGTGCGCCGTTATGTTAATTGGGCACCGAGTCAACTTGAGCAAATCGAGCTGTTAGAGCAATTGCGAG
TGTTGTGGTACGGTGAAAAAATTCACGTTGCTGTGGCAAAAGCAGTACCCGCAGTTGGCGTTGATACCCAAGAAGATTTG
GACAGAGTTAGAGCCATTATGCTCAATAAATAA

Protein sequence :
MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALESGASQVIVATDHPEVVTAVEAAGGEVCLTRADHQSGTERLA
EVIERYGFADDQIIVNVQGDEPLVPPEIIRQVAENLAASSAGMATLAVPIESSEEAFNPNAVKVVMDAQGYALYFSRAAI
PWERERFAQSKETIGDCFLRHIGIYAYRAGFVRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQEDL
DRVRAIMLNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-29 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-29 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-30 45