Gene Information

Name : metB (YE1469)
Accession : YP_001005776.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Resistance
Product : putative cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1649022 - 1650167 bp
Length : 1146 bp
Strand : -
Note : Similar to Xanthomonas campestris cystathionine gamma-synthase UptH SWALL:Q93S80 (EMBL:AF204145) (399 aa) fasta scores: E(): 3.8e-91, 63.73 38d in 375 aa and to Helicobacter pylori cystathionine gamma-synthase MetB or hp0106 SWALL:METB_HELPY (SWALL:P56069

DNA sequence :
ATGGCAAAGTTCGATACCTTAACCGTCCATGCCGGTTATACCCCAGACAGCACCGGTGCAGTGATGCCCGCAATTTATGC
GACATCCACTTTCGCACAACCGGCCCCCGGCGAGCACACCGGGTATGAATATTCCCGCAGTGGTAACCCGACACGCACCG
CACTGGAAAAAGCGATTGCAGAATTAGAAGGCGGCATTCGTGGTTATGCTTTTGCTTCTGGCTTAGCCGCCTGTTCGACC
GTTCTGGAACTGCTGGATCAAGGTAGTCATATCATTGCTGTGGATGATTTATACGGCGGCACCTACCGTCTGCTGGAGAA
AGTGCGCAGCCGCACTGCTGGTTTACGAGTCACTTATGTCTCACCTGCGGATACCGCTGCCTTAGAACAGGCCATTTTAC
CTGACACCAAAATGATCTGGGTGGAGACGCCAACTAACCCATTGTTAAAATTGGCGGATCTGACAGCGATTGCGGCTATT
GCCAAGAAACATCGATTGATTAGTGTGGCAGACAACACCTTTGCCTCTCCTTATATTCAGCGCCCACTGGATTTAGGATT
TGATATTGTGGTGCATTCAGCCACCAAATACCTGAATGGTCACTCAGATGTCGTCGCGGGTGTCGCGGCGGTAGGCAATA
ACCCTGAATTGGCCGAACAATTAGGCTTTTTACATAATGCAGTCGGCGGGATTTTAGACCCGTTCAGTAGCTTCCTGACA
TTGCGCGGTTTACGAACTTTGGCTTTACGTATGGCGCGACATAATGATAGCGCCCAGCGCATTGCCGAATGGCTTGAACA
GCAGCCGCAAGTGGAAAATGTGTATTACCCGGGGCTAAAAAGCCACCCGCAACACGCGCTGGCAGCCAAACAGATGGCCG
GTTTTGGCGGCATGATTTCAGTGCGATTGAAAGGCGATGATGAGTTCGCCCGCGCTGTTATTAAGCGCTCACATTTGTTT
ACGCTGGCCGAAAGCCTCGGTGGGGTTGAAAGCTTAATCAGCCAGCCCTACAGCATGACTCATGCCTCAATCCCACTGGA
AACGCGCTTAAAACATGGAATTACTCCACAACTATTGCGTTTGTCCGTTGGGATTGAAGACACCGAAGACTTGATTGCAG
ACTTAGACCAAGCGCTGAACGGCTAA

Protein sequence :
MAKFDTLTVHAGYTPDSTGAVMPAIYATSTFAQPAPGEHTGYEYSRSGNPTRTALEKAIAELEGGIRGYAFASGLAACST
VLELLDQGSHIIAVDDLYGGTYRLLEKVRSRTAGLRVTYVSPADTAALEQAILPDTKMIWVETPTNPLLKLADLTAIAAI
AKKHRLISVADNTFASPYIQRPLDLGFDIVVHSATKYLNGHSDVVAGVAAVGNNPELAEQLGFLHNAVGGILDPFSSFLT
LRGLRTLALRMARHNDSAQRIAEWLEQQPQVENVYYPGLKSHPQHALAAKQMAGFGGMISVRLKGDDEFARAVIKRSHLF
TLAESLGGVESLISQPYSMTHASIPLETRLKHGITPQLLRLSVGIEDTEDLIADLDQALNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-74 53
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-75 53
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-47 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_001005776.1 putative cystathionine gamma-synthase BAC0207 Protein 5e-57 44