Gene Information

Name : metB (YE0111)
Accession : YP_001004505.1
Strain : Yersinia enterocolitica 8081
Genome accession: NC_008800
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 121214 - 122371 bp
Length : 1158 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCAACCATAGCAGTGCGTAGCGGGTTGAACGATGACGAGCAATACGGCTGCGTTGTCCCCCCGAT
TCACCTCTCCAGTACCTATAATTTTATCGATTTTAATCAGCCACGCGCCCATGACTATTCTCGTCGCGGTAACCCGACGC
GTGATGTGGTGCAGCGGGCATTGGCTGAGCTGGAAGGGGGCGCAGGTGCGGTAATGACCAGCAGTGGGATGTCGGCGATT
CATTTGGTTTGTACTACTTTTCTCAAGCCGGATGATTTATTGGTTGCCCCACATGATTGTTACGGCGGCAGCTACCGTCT
ATTCGATAGCTTAAGCAAACGCGGCGCCTATCGGGTGCTGTTTGTTGACCAAGGCGATGAAGTGGCATTGAGTCAGGCAT
TGGCTAAAAAACCCAAGCTGGTATTGATTGAAACCCCAAGTAACCCGCTGTTACGGGTGGTGGATATCGCCGCTATCTGT
AAAGACGCGCATGCCGTCGGTGCATTAACGGTTTGCGATAACACCTTCCTTAGCCCGGCGCTACAGCAGCCGCTTGCTTT
GGGGGCGGATCTGGTGGTGCATTCCTGTACCAAATATCTGAACGGTCATTCTGATGTGGTGGCGGGTGCGGTCATTGCTA
AAGATCCTGAGTTGGCTGTCGAGCTGGCATGGTGGGCGAATAATATCGGGGTGACCGGTGCGGCATTTGATAGCTACCTG
TTATTACGCGGTTTGCGAACATTGTCGCCACGTATGGCTCAACAGCAACGTAACGCGGATGACATTGTTCGCTATTTACA
GCAGCAGCCTTTAGTGAAAAAGCTGTATCATCCTTCTCTGCTACAACATCCCGGCCACGAAATTGCCTGCCGTCAGCAGT
CAGGTTTTGGTGCGATGCTCAGTTTTGAGCTTGATGGTGATGAACAGGTACTGCGTCGTTTCCTCTCTGCCCTTGAATTA
TTTACCCTGGCAGAGTCTTTGGGGGGCGTTGAAAGCCTGATTTCCCATGCTGCGACCATGACCCATGCCGGTATGGCGCC
AGAAGCGCGCACTGCCGCCGGTATTACTGATAGTTTATTGCGCATTTCCGTGGGTATCGAAGACAGCGAAGATTTGATTG
CCGATTTGGACAATGCTTTCCGGTTGGCGAGAGACTGA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFIDFNQPRAHDYSRRGNPTRDVVQRALAELEGGAGAVMTSSGMSAI
HLVCTTFLKPDDLLVAPHDCYGGSYRLFDSLSKRGAYRVLFVDQGDEVALSQALAKKPKLVLIETPSNPLLRVVDIAAIC
KDAHAVGALTVCDNTFLSPALQQPLALGADLVVHSCTKYLNGHSDVVAGAVIAKDPELAVELAWWANNIGVTGAAFDSYL
LLRGLRTLSPRMAQQQRNADDIVRYLQQQPLVKKLYHPSLLQHPGHEIACRQQSGFGAMLSFELDGDEQVLRRFLSALEL
FTLAESLGGVESLISHAATMTHAGMAPEARTAAGITDSLLRISVGIEDSEDLIADLDNAFRLARD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-59 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-60 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-48 41