Gene Information

Name : guaA (Hhal_1681)
Accession : YP_001003247.1
Strain : Halorhodospira halophila SL1
Genome accession: NC_008789
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1834267 - 1835856 bp
Length : 1590 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAGCGATCAGTCCGGGGCGGATATTCACGCCCACCGTATCCTTATTCTCGATTTCGGCTCGCAGTACACCCAGCTCAT
CGCCCGCCGCGTGCGCGAGTGCGGGGTGTACTGCGAGATCCGCGCCTGCGATGTCGCAGACCAGGCCGTGCGCGATTTCG
CCCCGTCCGGGGTCATCCTGTCTGGCGGCCCCGAGACAGTGACCGACGCAGAAACCCCGCGCATCCCGGCAGCGGTCTTC
GAGGTGGGCGTGCCGCTGCTCGGGATCTGCTACGGCATGCAGGCCATGGCCGCCCAGCTCGGGGGACGGGTCGCGCCCTC
CGAGCACAAGGAGTTCGGATACGCCCAGGTGCGTGCCCGCGGCCATTCGCGGCTGCTGCGCGATATCGAGGATCACGCCA
GCGCCGACGGCTACGGGTTGCTCGACGTCTGGATGAGCCACGGCGATCGGGTGGAGGCGCCGCCGGAGGGGTTCCTGGTG
ATCGCCGAGACCGAGGCCGCCCCGGTGGCCGGCATCGGAGACGATGATCGCGGCTGGTACGGGTTGCAGTTCCACCCGGA
GGTCACCCATACCGCGCAGGGAGGGCGCATCCTCGAGCGTTTCGTCCGCGAGATCTGCGGCTGTCCGGGGGACTGGACTC
CGGGGAATATCGTCGAGGACAGCATTGCCCGGGTGCGCGAGCAGGTCGGCGACCGCCACGTCGTCCTCGGGCTCTCCGGC
GGAGTGGATTCGTCGGTGACCGCCGCTCTGCTGCACCGAGCGATCGGCGACCAGCTGACGTGCGTGTTCGTCGATAACGG
CCTGCTGCGCCAGGGGGAGGCCGACCAGGTGATGGCCACCTTCGCCCGTCACATGGGCGTGCGGGTGATCCATATCGATG
CTGAGGACCGTTTCCTAACCGCCCTGTCCGGGGTCGAGGATCCTGAGGAGAAGCGGCGGATCATCGGCAACCTGTTCGTC
GAGATCTTTGACGAGGAGGCCGGAAAGCTCCAGGGCGTCGATTTCCTCGCCCAGGGTACGATCTACCCCGACGTGGTGGA
GTCGGCGGGCAACGCCGGAGGTAAGTCTCACGTCATCAAGTCCCACCACAACGTGGGCGGACTGCCCGAGACCATGAAGC
TCAAACTCGTCGAGCCGCTGCGCGAGCTGTTCAAAGACGAGGTGCGGCGGGTTGGGCTGGAGCTGGGGCTGCCGGCAGAC
ATGCTCTACCGTCACCCCTTCCCGGGGCCGGGGCTGGGGGTGCGCATCCTGGGCGAGGTCCACAAGCGCTACGCCGATCT
GCTGCGACGGGCAGATGCGATCTTCATCGAGGAGCTGCGTCGGTGGGACTGGTACGACCGTACCAGTCAGGCCTTTGCGG
TCTTCCTGCCGGTGCGCTCGGTGGGCGTGACCGGGGACGGGCGGCGCTATGAGTACGTGGTCGCCCTGCGCGCCGTGGAG
ACCGTGGATTTCATGACCGCGCGTTGGGCGCAGCTGCCGTACGAGTTCCTCGATCACGTCTCCCGGCGGATCATCAACGA
GATCGACGGCATCTCCCGCGTTGTCTACGACATCTCGGGCAAACCTCCGGCGACCATCGAGTGGGAGTGA

Protein sequence :
MSDQSGADIHAHRILILDFGSQYTQLIARRVRECGVYCEIRACDVADQAVRDFAPSGVILSGGPETVTDAETPRIPAAVF
EVGVPLLGICYGMQAMAAQLGGRVAPSEHKEFGYAQVRARGHSRLLRDIEDHASADGYGLLDVWMSHGDRVEAPPEGFLV
IAETEAAPVAGIGDDDRGWYGLQFHPEVTHTAQGGRILERFVREICGCPGDWTPGNIVEDSIARVREQVGDRHVVLGLSG
GVDSSVTAALLHRAIGDQLTCVFVDNGLLRQGEADQVMATFARHMGVRVIHIDAEDRFLTALSGVEDPEEKRRIIGNLFV
EIFDEEAGKLQGVDFLAQGTIYPDVVESAGNAGGKSHVIKSHHNVGGLPETMKLKLVEPLRELFKDEVRRVGLELGLPAD
MLYRHPFPGPGLGVRILGEVHKRYADLLRRADAIFIEELRRWDWYDRTSQAFAVFLPVRSVGVTGDGRRYEYVVALRAVE
TVDFMTARWAQLPYEFLDHVSRRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-127 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-127 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-127 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-114 48