Gene Information

Name : Veis_3131 (Veis_3131)
Accession : YP_997880.1
Strain : Verminephrobacter eiseniae EF01-2
Genome accession: NC_008786
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : 3.1.21.3
Position : 3479380 - 3482562 bp
Length : 3183 bp
Strand : +
Note : KEGG: xom:XOO_3254 type I restriction-modification system endonuclease; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like

DNA sequence :
ATGGCGTTTTTGGCCGAAGCCGACATTGAGCAAGCCCTGCTGACGCAGTTGCGCAGACTAGGCTACTCCATCGCATCCGA
CGATGTCATTGGTCCGGACGGCAACGCGCCGGAACGCGAAAGCCACGATGTCGTCGTGCTGCATAAGCGGCTGGAAACCG
CTGTGCTGCGGCTCAATCCCGCTTTGCCGCCGGAAGCGCGGGCAGATGCCATTCGCAAACTGACTCAATCGGAATTCCCC
GCCCTGCTGGAAGAAAATCGTCGCATCCACACCCTGCTGACCGAGGGCGTGGACGTTGAATACTACGGCGACGATGGTGT
ACTGACGGCGGGCAAGGTTCGGTTGCTGGATTTCGATACACCGGAAAACAACGACTGGTTGGCCGTGCAGCAGTTCGTGG
TCATCAACGGCCAAGTCAACCGCAGGCCGGATGTGGTGCTGTTCGTCAACGGCCTGCCGCTGGCGGTCATCGAACTCAAA
GCGCCGGGCAGCGCGGGCGCGCATCTGGCGGGCGCGTTCAACCAGTTGCAGACTTACAAGCAGCAGATTCCGGCGCTGTT
TCACACCAATGCGCTGCTGGTCACTTCGGACGGCATTGCCGCGCGCGTGGGGTCGCTGTCCGCCGATCTGGAACGCTTCA
TGCCGTGGCGCACCACGGATGGCAGCGCGATTGCGCCCAAGGGTTCGCCGGAGTTGGCAACGCTGATCGAGGGCGTGTTC
GCGCCGCAACGCTTCCTCGACCTGCTACGGTATTTCACCGTATTCGGCGAGACCGGCTCGGGTCTTACGAAGATCGTGGC
GGGCTATCACCAGTTCCACGCGGTCAATCGTGCCGTCGAATCCACCATTCGCGCATCAAGCCAATGGCAGGGCGTGCGCG
AGGAACCGGCCTCGTATGGCCTGCCCAGCGTGGCGATGCAAGCCCGTGGCGACCGGCGCGCGGGCGTGATCTGGCACACG
CAAGGCTCCGGCAAAAGCCTGCTGATGGCCTTTTACGCCGGGCGGCTGGTGCAGCACCCGGCGATGGAGAACCCGACGCT
CGTCGTGCTGACCGACCGCAACGATCTGGACGACCAGTTGTTCTCCACCTTCTCGATGTGCCGCGACCTGATCCGGCAGA
AACCGGTGCAGGCCGAAGGCCGCGAGCATTTGCAACAACTGCTGGCGCGCGCTTCCGGCGGCGTGATCTTCACTACCTTG
CAGAAGTTTGGCGAGGTAGCCGAGCCGCTGACCACGCGGCGCAATGTGGTCGTCATCGCCGACGAAGCACACCGTTCGCA
ATACGGTTTCCGCGCGAAGGTGGATGCCAAGACTGGCGAGGTGAGCTACGGCTTCGCCAAATACCTGCGCGATGCGCTGC
CCAATGCCTCGTTCATCGGCTTTACGGGCACGCCCATCGAGGCGACGGACGTGAACACCCTGGCGGTGTTCGGCAACTAC
ATCGACGTGTACGACATCAGCCGCGCGGTGGAAGACGGCGCGACCGTGCCGATCTACTACGAATCGAGGCTGGCGCGCAT
CGAACTCGACGAGGACGAAAAGCCCAAGCTCAACGCCGAAGTCGAGGCGTTGACCGAGGACGAGGCCGTCACCGAGCAGG
AAAAGCTGAAGGCGAAATGGGCAACGGTCGAAAAACTGGTCGGCAGTGACAAACGCCTCGCGCTGGTGGCGCAGGATTTG
GTGGCGCATTTCGAGGACAGGCTGACCGCGCTGGACGGCAAGGCCATGGTGGTGTGCATGAGCCGCCGTATCGCCGTAGC
GCTATACGATGAAATCATCAAGCTGCGCCCGGACTGGCACAGCACGGACGATGCCGCAGGCGCGGTGAAAATCGTGATGA
CCGGTGCGGCCAGCGACCCACCCGCTTGGCAGCAGCACATCGGCAACAAGGCGCGGCGCGATCTGCTGGCCAAGCGTGCG
CGTGACGCGAAAGACCCGCTGAAACTGGTCATCGTGCGTGATATGTGGCTGACCGGCTTTGACGCGCCGTGCATGCACAC
GATGTATGTCGATAAACCGATGCAGGGTCACGGGCTGATGCAGGCCATCGCGCGCGTGAACCGCGTGTTCCTCGACAAGC
CTGCTGGGTTGATCGTGGACTACATCGGCATCGCGCAAAGCCTGAAATCCGCGCTGGCGCAGTATTCGGCGGGTGACCGA
GCCAACACCGGTGTGGACGAAGCGCAGGCCGTGGCGGTGATGCAGGAGAAGTACGAAGTAGTGCGCGACATGTACCACGG
CTTCGACTACGCCACCGCCTTGAACGGCACGCCGCAGCAGCGGCTGGCGATGATGGCTGGTGCCATCGAGTGGATACTCG
ACAAGCAGCAGCAATGGACGGCTGCGGAAACCACGGATGAAGGCAAGAAGAACGCCCAGCGCCGCTATCAGGATGCGGTG
CTGGCCTTGTCGAAGGCGTACTCGCTGGCGTCGGCTTCGGACGAGGCGCGCGGCATCCGCGAGGAGATTGGCTTCTTCCA
GGCCATCCGTGCGGCGCTGGTGAAGTCGGCGACAGGCTCGGGCGTCACCTCGCAGGAGCGCGACTTCGCTATCCAGCAGA
TCGTCAGCCGCGCAGTGATTTCGACCGAGATCGTGGACATCCTCAAGGCGGCGGGCATCCAAAGCCCGGACCTCTCCATC
CTGTCCGACGAGTTCCTCGCCGAAGTGCAGCAGATGCAGAAGAAGAACCTTGCGCTGGAAGCCTTGCGCAAGCTCATCAA
CGACGGCATCCGCTCGCGCAGCAAGGCCAACATCGTGCAGACACGCGCGTTCTCGGAGCGGCTGGAAGATGCCGTGGCGC
GCTACCACGCCAATGCCATCACCACCGCCGAAGTGTTGCAGGAACTGATTCAGTTGGCGAAGGACATCCGCGCGGCGCGG
CAGCGTGGCGAAGAAGCGGGCCTGTCCGATGAGGAAATCGCCTTCTACGACGCGCTGGCCGAAAACGAAAGTGCGGTGCA
GGCAATGGGCGACGACAAGCTCAAGGTCATTGCCCACGAATTGCTGGGCAGCCTGAAAGGGAACGTGTCCGTGGATTGGG
CGCATCGCGATTCGGCGCGCGCCCGGATGCGGGTGCTGGTCAAGCGCATTCTGCGCAAATACGGTTATCCGCCGGATTTG
CAGGATGCGGCGGTGCAGACCGTGCTGCAGCAGGCCGAGGCGCTCTCGGCTGGATGGATTTAG

Protein sequence :
MAFLAEADIEQALLTQLRRLGYSIASDDVIGPDGNAPERESHDVVVLHKRLETAVLRLNPALPPEARADAIRKLTQSEFP
ALLEENRRIHTLLTEGVDVEYYGDDGVLTAGKVRLLDFDTPENNDWLAVQQFVVINGQVNRRPDVVLFVNGLPLAVIELK
APGSAGAHLAGAFNQLQTYKQQIPALFHTNALLVTSDGIAARVGSLSADLERFMPWRTTDGSAIAPKGSPELATLIEGVF
APQRFLDLLRYFTVFGETGSGLTKIVAGYHQFHAVNRAVESTIRASSQWQGVREEPASYGLPSVAMQARGDRRAGVIWHT
QGSGKSLLMAFYAGRLVQHPAMENPTLVVLTDRNDLDDQLFSTFSMCRDLIRQKPVQAEGREHLQQLLARASGGVIFTTL
QKFGEVAEPLTTRRNVVVIADEAHRSQYGFRAKVDAKTGEVSYGFAKYLRDALPNASFIGFTGTPIEATDVNTLAVFGNY
IDVYDISRAVEDGATVPIYYESRLARIELDEDEKPKLNAEVEALTEDEAVTEQEKLKAKWATVEKLVGSDKRLALVAQDL
VAHFEDRLTALDGKAMVVCMSRRIAVALYDEIIKLRPDWHSTDDAAGAVKIVMTGAASDPPAWQQHIGNKARRDLLAKRA
RDAKDPLKLVIVRDMWLTGFDAPCMHTMYVDKPMQGHGLMQAIARVNRVFLDKPAGLIVDYIGIAQSLKSALAQYSAGDR
ANTGVDEAQAVAVMQEKYEVVRDMYHGFDYATALNGTPQQRLAMMAGAIEWILDKQQQWTAAETTDEGKKNAQRRYQDAV
LALSKAYSLASASDEARGIREEIGFFQAIRAALVKSATGSGVTSQERDFAIQQIVSRAVISTEIVDILKAAGIQSPDLSI
LSDEFLAEVQQMQKKNLALEALRKLINDGIRSRSKANIVQTRAFSERLEDAVARYHANAITTAEVLQELIQLAKDIRAAR
QRGEEAGLSDEEIAFYDALAENESAVQAMGDDKLKVIAHELLGSLKGNVSVDWAHRDSARARMRVLVKRILRKYGYPPDL
QDAAVQTVLQQAEALSAGWI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 49
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 48
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 48
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 47