Gene Information

Name : lysS (Veis_3052)
Accession : YP_997803.1
Strain : Verminephrobacter eiseniae EF01-2
Genome accession: NC_008786
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 3404965 - 3406548 bp
Length : 1584 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCTTGCGAACGCCTCAGCCTGCGGGCGGTCTTTCATGTCTGACAACCATCCATCTCCCCACACCGCCCCGGACGAAAA
CCAGCTCATTGCCGAGCGCCGTGACAAGCTGCATGCGCTGCGCGCCGCGCAAGCCGAAGGCGGCGGCGTTGCCTTTCCGA
ACGATTTCAAACCCTCGCACCAGGCCGCGCAGTTGCATCTGGCCCATGGCGCGGCCACGGCGCAGGCGCTGCAAGCCGCT
GCCGTCAGCGTTGGCGTGGCCGGCCGCATGATGCTCAAGCGCGTGATGGGCAAGGCCAGTTTTGCCACGCTGCAAGACGG
CTCGCTCGGCGCAACGGGCGGGCGTATCCAGTTGTACGTCACCAGCGATGCGGTGGGCCAGGCGCGATACGCCGATTTCA
AGCATTGGGATCTGGGCGACATCGTGGGCGCCGAAGGCACGCTGATGAAGACCCGCACGGACGAGTTGTCGATCAAGGTG
ACCCGGTTGCGGCTGCTGACCAAGAGCCTGCGCCCGCTGCCCGACAAGTTCCATGGCCTGGCCGACCAGGAACAAAAGTA
CCGCCAGCGCTATGTCGACCTGATCACCGACGCCCAGGCGCGCCAGCGCTTCGTGGCACGCAGCAAGGCCGTCAGCGACC
TGCGCGAGTTCATGGTGGGCCATGGCTTTCTGGAAGTCGAAACGCCGATGCTGCACCCGATACCCGGTGGCGCCAACGCC
CGCCCCTTCGTGACGCACCACAACGCGCTCGAACAGCAGATGTACCTGCGCATAGCGCCCGAGCTGTACCTCAAGCGCCT
GATCGTCGGCGGCTTCGAGCGCGTGTTCGAGATCAACCGCAGCTACCGCAACGAGGGCATCTCGGTGCGCCACAACCCCG
AGTTCACGACGCTGGAGTTCTACGCGGCCTACTGGAACTACCTCGATGTGATGGACTTCACCGAGACGCTGATCCGCGCC
GTGGCGCTCAAGGCCACAGGCTCGCTGCAAATGAGCTACCAGGGCCGGGCCGTGGACCTGGCACAACCGTTTGCGCGCCT
GAGCATTCGCGAAGCCATCTTCCAGCACACCGAGGCCGGCGCCCATGTCGATGACGCCGCCTGGCTGATCAGCGCGCTCA
AAAAGCTGGGCCGCACGCAAGAAGCCGACAAGCTCTCAAGCCGCACGCTGGTCAGCCTGCAACTGCTGTACTTTGAAGAG
ACGGTGGAAGACAAGCTGTGGCAGCCGACCTTCATCATGGAGCACCCCACCGAGATCTCTCCATTGGCGCGCGCCAACGA
CCTGCGCCCCGAGGTCACGGAGCGCTTTGAGCTGTACATCACCGGCCGCGAATTCGGCAACGGCTTCAGTGAACTGAACG
ACGCCCAGGAGCAGGCCGCACGCTTTCACACCCAAGTGGCCGCCAAGGACGGCGGCGATGACGAGGCCATGTTCCATGAC
CATGACTTCGTGCGCGCGCTCGAATATGGCATGCCCCCCACCGGGGGCTGCGGCATCGGCATCGATCGCCTGATGATGCT
GCTGACCGACAGCCCCAGCATCCGGGACGTGATCCTGTTCCCGGCGCTGCGCAGACAGGTATGA

Protein sequence :
MLANASACGRSFMSDNHPSPHTAPDENQLIAERRDKLHALRAAQAEGGGVAFPNDFKPSHQAAQLHLAHGAATAQALQAA
AVSVGVAGRMMLKRVMGKASFATLQDGSLGATGGRIQLYVTSDAVGQARYADFKHWDLGDIVGAEGTLMKTRTDELSIKV
TRLRLLTKSLRPLPDKFHGLADQEQKYRQRYVDLITDAQARQRFVARSKAVSDLREFMVGHGFLEVETPMLHPIPGGANA
RPFVTHHNALEQQMYLRIAPELYLKRLIVGGFERVFEINRSYRNEGISVRHNPEFTTLEFYAAYWNYLDVMDFTETLIRA
VALKATGSLQMSYQGRAVDLAQPFARLSIREAIFQHTEAGAHVDDAAWLISALKKLGRTQEADKLSSRTLVSLQLLYFEE
TVEDKLWQPTFIMEHPTEISPLARANDLRPEVTERFELYITGREFGNGFSELNDAQEQAARFHTQVAAKDGGDDEAMFHD
HDFVRALEYGMPPTGGCGIGIDRLMMLLTDSPSIRDVILFPALRRQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-119 53
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_997803.1 lysyl-tRNA synthetase VFG1668 Protein 4e-119 53