Gene Information

Name : Veis_2437 (Veis_2437)
Accession : YP_997201.1
Strain : Verminephrobacter eiseniae EF01-2
Genome accession: NC_008786
Putative virulence/resistance : Virulence
Product : amino acid adenylation domain-containing protein
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1020
EC number : -
Position : 2764741 - 2771343 bp
Length : 6603 bp
Strand : -
Note : TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Methyltransferase type 12; Non-ribosomal peptide synthetase; KEGG: pst:PSPTO_2602 yersiniabactin non-ribosomal pept

DNA sequence :
GTGGCCGCCCGCGCGCCGGGCCGGCCTGGAACAACCTACACGACCTCCCCTGTGACACCTGACACCGATCTGGACCTCCC
CCGCGAGGACCTCGCACCCACCACCAAGCCCGGCACGGGTCTGGCGACCCAACCAACCCTGCGCGACGAACTCGCGGCAG
ACCTGGACATCCCGGTAGCGCAACTGGACGAGCACACCAGCCTGATCCAGCTAGGCATGGACTCCATGCACCTGATGGCC
TGGCTGAACCGGCTGCGCCAGCGCGGCCACGAGGTGACGCTGCGGCAGCTGTACGGCGAGCCCACCCTGGCTGGATGGAG
CCGCCTGCTGCAGCAGAAGGCGGGCGGCGCCCGCGCGCGCGCTGCCGCGCCGCCCGCCTGGCCGGTCATGCGGGACGGCG
AGGCGTTCGAACTGACGCCGGTGCAGCACGCCTACTTGGTCGGCCGCTCCCCCCAGCAGACGCTGGGCGGCGTCGGCTGC
CACCTCTACCAGGAATTCGACGGCACCGGCCTTTCCGTCCCGGCGCTGGAATCGGCGGCCCAGGCGCTGATAAAGCGCCA
TCCGATGCTGCGCGTGGCCTTCCGCAGCGATGGCCTCCAGCAGTATGGCGAGCAGACGCGGTGGCCCGGGCTGGCCCTCC
ACGATCTGCGGGCGCTGGACAACAGCGCGCGGCAGGCCCGGCTGCTGGACCTGCGTGAGCGGCTGGGGCACCGGGTGCTG
GCCGTCGAGCGCGGCGAAACCATCGACTTCCAGCTCTCGCTGCTGCCCGAAGGAAGGCATCGGCTGCACGTCAACATCGA
TCTGCTCGTGCTCGACGCCGCCAGCTTCACCCTGGTGTTCGAGGAACTGGCGGCCCTGCTTCGCGGCGACACGCCCCCTG
CGCCCGGTGCAGGCTACGACTTCCGCAGCTATCTCGTGCAGCTGCGCGAAGAGACCGGCGACGCGCGCGAGCGGGCACAG
CGCCACTGGCTCGGCCGGCTGGACGATCTCCCCTGCGCGCCGGCCCTGCCGCTGGCATGCGAGCCGGAGCGCAGCGGCCC
CGTACGCGTGCTCCGGCGCCGCGCCGAGCTGAATGCTGGCGATTGGGAAAGATTCAAGGCCCATGCCGGCGCGAGCGGCG
TGACACCCACCATGGCGCTCGCCACCTGCTTCGGCGCAGTGCTGGCGCGCTGGAGCAACCAGCCCCGGCTCCTGCTCAAC
CTCACCCTGTTCGACCGCCAGCCACTGCACCCGTCCGTCGAGCGCATGATCGCGGACTTCACCAACGTCCTTCTGCTGGA
CCTCTTTTGCGAAGGCGCTGCATTCGACGCGCTCGCGCGGAGCAATCAGGACACCTTCGCCGACGCCTACGAACACCGCC
ACTGGTCCGGCGTTGAACTGCTGCGCGAGCTGCGCAAGGCACAGACCCATCCCCACGGTGCGCCCGTGGTGTTCACCAGC
AATCTCGGCCGTCCGCTATACGGCCACGGCACGGCTGCCGTGCTGGGCCAGCCCGGCTGGGGCATCTCCCAGACGCCCCA
GGTCTGGATCGACCACCTGGCGTTCGAGCACGGCCCGTCGGTCTGCCTGCAATGGGACAGCAACGACGCGCTCTTCCCGG
ACGGCCTGGTCGATACGCTGTTCGACACCTATATCGCACAGGTCCGCCGGCTCGTGGACGACACGCACGCGTGGCAAGCG
CGCCTGCCGGACCCCATGCCCGCCTCGCAGCGCGACGTGCGCTCGCGCATCAACGACACGGCGCAGCCCGTGCCGCAAGG
GTTGCTGCACCACGGCTTCTTCAGTGCCGCAGAACGCACCCCCCAGGCCATCGCCCTCATCCAGGGCACGCGCTCGCTGA
CCTACGCCGAACTGGCCGAACAGGCACGGCGCTGCGCGGGCGCGCTCGCCGCCCGCGGCGTGCACGCCGGCGACACGGTC
GCGATCGCCATGTCCAAGGGCATCGGGCAGGTGATCGCGGCGCTGGGTGTGCTGCATGCCGGCGCGGTCTACGTGCCCAT
TGCGCTCGACCAGCCCGCGGAGCGCCGCCGCAAGATCCACCGCGACGCGGGCGTCGCCGTGGTGATGACCTGCCGGGACG
ACGCGGAACCCGGCGCCGTGCACGATGGCGGCTCGGACGGCACCGACCCACCCGCTCTCTGCTGGCAGGACGCCATCCTG
CACGCGGGCCTGCACGCCCCCGCCACCGTGGACCCAGGACACCCCGCCTACGTCATCTACACCTCCGGCTCCACGGGCGC
ACCGAAGGGGGTCACCATCTCCCACCGGGGCGCGCTCAATACCTGCGCCGACCTGAACCAGCGCTACCGCCTCGGCGCCA
GCGACCGCGTGCTGGCGCTGTCCGCGCTGCACTTCGACCTGTCCGTCTTCGACATCTTCGGCCTGCTGGCCGCGGGCGGC
GCACTGGTGCTCGTGGGCGAGGCCCAGCGCCGGGACCCCTCGGTGTGGTGCGACATGATCGAGGCCCACGGCATCACGGT
CTGGAACACCGTGCCAGCGCTCTTCGACATGCTGCTCACCTACAGCGAGGGCTTCGATCTGCGCGCGCCCGGCCGGCTCC
GCATGGCGGTGCTCTCCGGCGACTGGATCGGACTCGACCTGCCCCGGCGCTACCGGGCTTTCCGCCCCGACGGCCAGTTC
ATCGCGATGGGCGGCGCCACCGAAGCCTCGATCTGGTCGAACGCCTACGACGTGCAGGACGTGCCGCCGCACTGGCGCTC
CATCCCCTACGGCTACCCGCTCGCCAACCAGAGCTACCGCGTCGTCGACGAACAGGGCCGCGACTGCCCCGACTGGGTGG
CCGGCGAACTCTGGATCGGCGGCGAAGGCGTCGCGCTGGGCTACTTCAACGACCCCGAGCGCAGCACCCGGCAGTTCGTC
ACGGCACAGGGCGGCCGCTGGTACCGCACCGGCGACATGGGCTGCTACTGGCCCGACGGCACCCTGGAGTTCCTCGGCCG
CCGCGACAAGCAGGTGAAGATCGGTGGCCACCGCATCGAGCTGGGTGAAATCGAAACGGCCCTGCACCGCATCGACGGCG
TGAAGAGCGCCGTTGCGCTGGCCCTGGGCGAGCGCGACCAATCGCTGGCCGCCTTCGTCGTCGCGCAGGGCGATGCACTC
CGGAGCCCACGGCACGCCGACCCGGCCCTGCCCGCCCATTACGGCACTCTGTTCGAACCCATCGCCGCCCCGGCGGACCG
CGAACCGGACACCGAGCGCCTCGTCGCCGACTTCCTGCTTGACCATCTGCGGCAGCAGGGCCTGGACTTCGCCACGCCTT
TCGACGCCGACGAAGCCCTGCGGCGCCAGGGTGCCGCGCCGCGCTGGCGCGGCCTGGTGCAGCGCTGGCTGGACCTGCTG
GTCCGCCAGAAACGCCTCGCCCGCGATCCGCAGCGCCGGGGCTTCGTCCGCGGGCCGCGCCACGGCGCCGCGCCCTGGCA
GCCCGCCAGCGATGATCCGCTGTGCGCCACGGCGGACGCCCTGCTCGCGCACCATGAGGCCCTTGCGCTCATCCTCCAGG
ACCGGCGACCGGCCTTCACGCTGCTCGAGCATCCGTTCTGGGCCCCCGAGCGGCTCCTGCTGCAAAGCCCGGGCACGGCC
GCCGCGATCGACGCGCTGGCCGATGCGCTGGCCGCGCTCGCGCTCGCGCTGGGCCGGCCCGTGCGTGCCGTCGAGATCGG
TGCGCGCAGCGGCCTCGCCGCCGAACTTCTGCTGCGCCGCCTCGGCGTGGACCAACTCGCCTACACCGCGCTGGATACTT
CGCAGGACATGGTGCTGCGGGCCGCTGGCCGCCTTGCCGCATACCCCCACGCCAGTGTGCGGCGCTGGGACGGAACCGCG
CAGGCGGATCTGGCCCACCATGCCGACGTGGTGTGGGCCGGCAATGCCCTGCACCGGCTCGGCGGCGATGCGCTGGATGC
CCTCCCTGCGCTGGCGGCGCCGGCCGCGCTGATCCACGTGCTGGAGCTGCGCAACGCGTCCTGCCTCGCCCTGGTCAGCG
CCGACCTGCTATCGCAGGATGGGGAAGACCTCGGCACCCACTTGCGCGACGCCGAGGGCTGGCAGGCCACGTTCCAGGCG
CGCGGCCTGCGCAGCGAACGGGCCGATGGGGCGGGCGACCAACAGCGCTTCGTGCTGCGCGCGCCCGACGAAATCCGGCA
ACCCGACCCGCGTAAGCTCTCCGAGGCGCTGGCGACGCAGTTGCCGCCGTACATGGTGCCCCAGCGGCTGGTGTTCCTGG
ACGCGCTGCCGCTCACCGCCAACGGCAAGATCGACCACAAGGCCCTGGGCGCCCTCTGCCAGCGCACGCCGGCCGCGCAG
GCGCAGCAGGAGCCCCCGCGCGGCGATGCCGAGGCTGCCGTCGCGGCACTGTGGCGCGAGATGCTGCGCGCGCCGACCGT
GCATCGGCACAGCCACTTCTTCCAACTCGGCGGCGACAGCCTGCTGGCCACCCGCCTGATTGGCGGGCTGGACCGGTCCG
GCTTTGAAGCCCGCCTGGGCGATCTGTTCGACTACCCCACGCTCGCGGCCTTCGCGGCCACGCTGCGCCCGCACGGCGAC
CGTGGCGCCGACGTGCTGCGGCATGAACCGGCATCGCGCCACGAACCGTTCGCGCTCACCGACGTGCAGCAGGCCTATCT
CGTGGGGCGCCAGCCCGGCTTCCCGCTCGGCGGCGTGGGCTCCCACTTCTTCGTCGAATTCGAGGTGGAGGGCCTGAACG
CCGCCCGCTTCGAGGCCGCCTGGAACCGGCTGATCGCACGGCACGACATGCTGCGTGCCGTGGTGCGCGACGGCCGGCAG
CAGGTGCTGGCCGAGGTGTCGCCGTTCTCGCTGCTACGCCACCACGTCCCCCGCCTCGACCACCCGGATGTCGACGCACT
GCGCGAGCGGCTCTCCCAGCAGGTGCTCGATCCCTCGCGCTGGCCCGTGTTCGATGTGCAGGCGGCCGAGGACGGCAGCA
GCCGCACCCGCCTGTTCGTCTGTCTCGACAACCTCATGCTCGACGGGCTGAGCATGCGGCTCCTGCTGACCGAGCTAGAG
CAGCTGTACCTTGACCCCGACAGCTGCCTGACGCCGCTGGAGATTGGCTTTCGCGACTACCTGTCCCACATCGCCGGCCA
GGGCCCCGGCGAGGCCTCGCTGGCGTACTGGCAGCGGCGGCTGGACAGCCTGCCGGCCGCGCCGCAACTGCCGCTGCGCC
GCGATCCGGCCGAGATCGGTGTACCGCGCTTCGTGCGCCTGTCCGACAGCCTCGGCACCCGCGACTGGCTGGCGCTTCAG
GCGCGCGCCAGCGAAGCGGGCCTGACGCCCTCGGCGCTGCTGCTGTCCGCCTACGCCGCCGTCCTGTCCGCGTGGAGCGC
ACACAGCGAGCTGTGCGTGAACCTCACGCTGTTCGACCGGCGTCCGGTGCATCCCCAGATCGAACGCGTGCTGGGTGACT
TCACCTGCCTGCTGCTGCTGGCCTGGCAGCCCGCTGCGGACTGGCGCGCCAGCGCGCAGCGGCTGCAGCAGCGCCTGCGG
CAGGACCTGGCGCACCGTGACGTCTCCGCCATCCGCGTCATGCGCGACCTAGTGTCGCGTCACCGATCATCTGTCGGTCT
GCGCTGGCCATCGAAGCGCATCGCGGCGTTGCATCGCTTGCCAATACGCTCGGTATTGGCTGCGCGATGCGCCTTGCGCT
GCGCTCCGATGGCTGCGCGCAGCCTACGACATCTGATCGGTGACGCGACACTAGCGCTGCGGCGGGGCCAGCCCGCAGCC
GCGATGCCCGTGGTGTTCACCAGCGCGATCGGCTTCGAGAGCGACCGATTCCTCGCGCAGGACTCGCCGCTGAAGCCGCG
CTGGGGCATCTCTCAGACGCCCCAGGTCTGGCTGGACCACCAGGTCTACGAATCCGCAGGCGAGCTGCGCTTCAACTGGG
ACGCGGTGGAGGCGCTGTTCGACCCCGCGCAGCTCTCGGCCATGTTCAGCCAGTACACGGCGCTCCTGCGCCGTCTGGCC
GGCGATCCTGCGGCCTGGGATCTGCCGCTCGATACCCTCGTGCCGCGTCACCGATCAGATGTCGTAGGCTGCGCGCAGCC
ATCGGAGCGCAGCGCAAGGCGCATCGCGCAGCCAATACCGAGCGTATTGGCAAGCGATGCAACGCCGCGATGCGCTTCGA
TGGCCAGCGCAGACCGACAGATGATCGGTGACGCGACACTAGTGCTGCGGGCGAACGCCCCTGCCGTGCCATGGGTGACT
CCCACCGTGGCCGCACAGGCCGCGGCAGAGCCACTGCCCGCCGACGCGGCACTGGTGGATGCGCTGCGCGACCATTTCCG
CCGCACCACGGGCCTGCCGATCGCGGCCCGGCAAACCTTCTTCGAAGCCGGAGCGTCCTCGCTGCAGCTCGTGCAGTTGC
ACATCCACCTGCGGCAGGCCGAGCACGGCGGCCTCGCGGTCACCGACCTCTTCGCGCATGCCACGCCCCATGCGCTGGCG
GCGCACATGGGTGCACTGGCCCGGCCACCGGCCGCTCCGCAGCACCCGCCGGAGCCCGAGCGGCGCACCCTGCTGGACCA
GCGCAAGGCCCGCGCGGAGCGCCGCCGGGCAGGATCGACATGA

Protein sequence :
MAARAPGRPGTTYTTSPVTPDTDLDLPREDLAPTTKPGTGLATQPTLRDELAADLDIPVAQLDEHTSLIQLGMDSMHLMA
WLNRLRQRGHEVTLRQLYGEPTLAGWSRLLQQKAGGARARAAAPPAWPVMRDGEAFELTPVQHAYLVGRSPQQTLGGVGC
HLYQEFDGTGLSVPALESAAQALIKRHPMLRVAFRSDGLQQYGEQTRWPGLALHDLRALDNSARQARLLDLRERLGHRVL
AVERGETIDFQLSLLPEGRHRLHVNIDLLVLDAASFTLVFEELAALLRGDTPPAPGAGYDFRSYLVQLREETGDARERAQ
RHWLGRLDDLPCAPALPLACEPERSGPVRVLRRRAELNAGDWERFKAHAGASGVTPTMALATCFGAVLARWSNQPRLLLN
LTLFDRQPLHPSVERMIADFTNVLLLDLFCEGAAFDALARSNQDTFADAYEHRHWSGVELLRELRKAQTHPHGAPVVFTS
NLGRPLYGHGTAAVLGQPGWGISQTPQVWIDHLAFEHGPSVCLQWDSNDALFPDGLVDTLFDTYIAQVRRLVDDTHAWQA
RLPDPMPASQRDVRSRINDTAQPVPQGLLHHGFFSAAERTPQAIALIQGTRSLTYAELAEQARRCAGALAARGVHAGDTV
AIAMSKGIGQVIAALGVLHAGAVYVPIALDQPAERRRKIHRDAGVAVVMTCRDDAEPGAVHDGGSDGTDPPALCWQDAIL
HAGLHAPATVDPGHPAYVIYTSGSTGAPKGVTISHRGALNTCADLNQRYRLGASDRVLALSALHFDLSVFDIFGLLAAGG
ALVLVGEAQRRDPSVWCDMIEAHGITVWNTVPALFDMLLTYSEGFDLRAPGRLRMAVLSGDWIGLDLPRRYRAFRPDGQF
IAMGGATEASIWSNAYDVQDVPPHWRSIPYGYPLANQSYRVVDEQGRDCPDWVAGELWIGGEGVALGYFNDPERSTRQFV
TAQGGRWYRTGDMGCYWPDGTLEFLGRRDKQVKIGGHRIELGEIETALHRIDGVKSAVALALGERDQSLAAFVVAQGDAL
RSPRHADPALPAHYGTLFEPIAAPADREPDTERLVADFLLDHLRQQGLDFATPFDADEALRRQGAAPRWRGLVQRWLDLL
VRQKRLARDPQRRGFVRGPRHGAAPWQPASDDPLCATADALLAHHEALALILQDRRPAFTLLEHPFWAPERLLLQSPGTA
AAIDALADALAALALALGRPVRAVEIGARSGLAAELLLRRLGVDQLAYTALDTSQDMVLRAAGRLAAYPHASVRRWDGTA
QADLAHHADVVWAGNALHRLGGDALDALPALAAPAALIHVLELRNASCLALVSADLLSQDGEDLGTHLRDAEGWQATFQA
RGLRSERADGAGDQQRFVLRAPDEIRQPDPRKLSEALATQLPPYMVPQRLVFLDALPLTANGKIDHKALGALCQRTPAAQ
AQQEPPRGDAEAAVAALWREMLRAPTVHRHSHFFQLGGDSLLATRLIGGLDRSGFEARLGDLFDYPTLAAFAATLRPHGD
RGADVLRHEPASRHEPFALTDVQQAYLVGRQPGFPLGGVGSHFFVEFEVEGLNAARFEAAWNRLIARHDMLRAVVRDGRQ
QVLAEVSPFSLLRHHVPRLDHPDVDALRERLSQQVLDPSRWPVFDVQAAEDGSSRTRLFVCLDNLMLDGLSMRLLLTELE
QLYLDPDSCLTPLEIGFRDYLSHIAGQGPGEASLAYWQRRLDSLPAAPQLPLRRDPAEIGVPRFVRLSDSLGTRDWLALQ
ARASEAGLTPSALLLSAYAAVLSAWSAHSELCVNLTLFDRRPVHPQIERVLGDFTCLLLLAWQPAADWRASAQRLQQRLR
QDLAHRDVSAIRVMRDLVSRHRSSVGLRWPSKRIAALHRLPIRSVLAARCALRCAPMAARSLRHLIGDATLALRRGQPAA
AMPVVFTSAIGFESDRFLAQDSPLKPRWGISQTPQVWLDHQVYESAGELRFNWDAVEALFDPAQLSAMFSQYTALLRRLA
GDPAAWDLPLDTLVPRHRSDVVGCAQPSERSARRIAQPIPSVLASDATPRCASMASADRQMIGDATLVLRANAPAVPWVT
PTVAAQAAAEPLPADAALVDALRDHFRRTTGLPIAARQTFFEAGASSLQLVQLHIHLRQAEHGGLAVTDLFAHATPHALA
AHMGALARPPAAPQHPPEPERRTLLDQRKARAERRRAGST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp2 YP_002346902.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 54
irp2 NP_669706.1 HMWP2 nonribosomal peptide synthetase Virulence HPI Protein 0.0 54
irp2 YP_070124.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 54
irp2 YP_001006815.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 54
irp2 CAA21390.1 - Virulence HPI Protein 0.0 54
irp2 YP_853075.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 0.0 54
irp2 NP_993007.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 54
PMI2599 YP_002152317.1 non-ribosomal peptide synthase Not tested Not named Protein 0.0 41