Gene Information

Name : thyA (BARBAKC583_0926)
Accession : YP_989208.1
Strain : Bartonella bacilliformis KC583
Genome accession: NC_008783
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 952215 - 953009 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAAGCTTATCTTGATCTTTTATCTCATGTTTTAAATAATGGCACCGATCGCTCAGATCGAACAGGTGTTGGAACACG
ATCAGTTTTTGGATATCAGATGCGGTTTAACTTGCAAGAGGGATTTCCTCTGTTAACGACAAAAAAATTGCATTTGCGAT
CAATTATTTATGAACTGTTGTGGTTTCTTAAAGGTGATACAAATATTGCGTGGTTAAAGGAACATGGCGTATCCATTTGG
GATGAATGGGCTGATAAAGATGGGAATCTTGGTCCTGTTTATGGTTATCAGTGGCGTTCTTGGCCTTCATCTGATGGGCG
TTATATTGATCAAATTAGTAATCTTTTGGCTATGATTAATCACAATCCTAATTCACGCCGCTTGATTGTGACAGCTTGGA
ATCCAGCATTAATAGATGAAATGGCGCTACCGCCTTGTCATTGTTTATTCCAATTTCAAGTCGCTAATGGTAAATTATCC
TGTCAACTTTATCAGCGTTCGGCAGATATTTTTTTGGGCGTTCCATTCAATATTGCTTCTTATGCTTTGTTGACGATGAT
GATTGCTCAAGTTACGGGGTTGAAAGTAGGGGATTTTATTCATACCCTTGGTGATGCTCATCTTTATTCTAACCATTTTG
AACAAGCAAAGCAGCAATTATCGCGTACACCGGGTATTTTGCCATTGATTCGCATAAATCCAAAAGTAACAGATCTTTTT
TCTTTTCAATTTGAAGATTTTGAGTTGCTTAATTATGAAGCTCAACCACACATCAAGGCACCGGTAGCAGTATGA

Protein sequence :
MKAYLDLLSHVLNNGTDRSDRTGVGTRSVFGYQMRFNLQEGFPLLTTKKLHLRSIIYELLWFLKGDTNIAWLKEHGVSIW
DEWADKDGNLGPVYGYQWRSWPSSDGRYIDQISNLLAMINHNPNSRRLIVTAWNPALIDEMALPPCHCLFQFQVANGKLS
CQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKVGDFIHTLGDAHLYSNHFEQAKQQLSRTPGILPLIRINPKVTDLF
SFQFEDFELLNYEAQPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 6e-78 62