Gene Information

Name : thiC (BARBAKC583_0446)
Accession : YP_988764.1
Strain : Bartonella bacilliformis KC583
Genome accession: NC_008783
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 450479 - 452314 bp
Length : 1836 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGCAAAAACATACTCCATCAGTTAGTTGTAGCCCTTTTCCTTCTTCGCACAAATTTTATCAACAAAGCCTTCTCTTTCC
TAACGTGCGCGTGCCATTACGTAAAATTTTATTGACAGATGGCAGCGGCGAGAGTCCTTTCAACGTCTATGACACTTCAG
GTCCTTACACCGATGAAAATGTGATCATTGATATCACGAAAGGATTGCCTGCAATCAGGATACCTTGGCTATCTGAGCGT
GCTGATACTGAATCTTACCCTGCTCGATTAGTTAAACCTGAAGATAATGGCTTTACCCATGGTAAAGACCTGACACCAGT
CTTTGAAAAAAAACGACCTATTTTGCGTTCAAAAAATGGTAAATCCATTACACAGATGACCTATGCACGGGCAGGTATTA
TCACTGCAGAAATGGAATATGTTGCAATACGTGAAAATGAAGGTCTGATAGAAAAAAACAAACAGCACACGACATCAAGT
AAAGCATTTGATGCATCAATACCGGAAGTCTATACAGCAGAATTTGTTCGCAATGAAATTGCCTGCGGGCGAGCCATTAT
CCCGCAGAATATCAATCATCCAGAATGCGAACCCATGATTATTGGGCGTAACTTTCGTGTTAAAATTAATGCTAATATTG
GAAATTCAGCAGTCACTTCATCCATGGCAGAAGAAGTAGAAAAAATGGTTTGGGCTATTCGCTGGGGAGCCGATACCGTT
ATGGATCTTTCAACGGGCCGTAATATTCATAATATTCGTGAGTGGATTATTCGAAACTCTCCAGTTCCTATAGGAACTGT
TCCAATTTATCAAGCACTTGAAAAAGTACATGGTATTGCTGAAAACCTAACATGGGATATCTTTCGCGATACTCTTATTG
AACAAGCAGAACAGGGCGTCGATTATTTCACTATTCATGCAGGATTAAAATTAGCTTTCATTCCTCTAACTATTGATCGC
ACAACAGGTATTGTTTCGCGAGGTGGTTCAATTATAGCCAAATGGTGCTTGCATCACCACAAAGAGAATTTTCTCTATGA
GCATTTTGATGAAATTTGTGATATTGCACACACATATGATGTATCTCTTTCATTAGGTGATGGATTGCGTCCTGGATCTA
TTGCTGATGCAAATGATGAAGCTCAATTTGCGGAGCTCAAAACTTTAGGTGAACTAACCCAAATTGCATGGGAAAAAAAT
GTACAGACCATGATTGAAGGACCTGGTCATGTTCCAATGCATAAAATTAAAGAAAATATGGATCAACAATTAGCTCTCTG
TAATGAGGCACCCTTCTATACTTTAGGCCCCCTTACAACTGATATTGCACCTGGATATGACCATATCACATCAGCCATTG
GTGCGGCCATGATTGGTTGGTTTGGAACAGCAATGCTCTGTTATGTAACACCTAAAGAACACTTAGGTCTACCAGACAAA
AATGATGTCAAAACTGGTGTCATCACTTATAAAATTGCTGCCCACGCTGCTGACCTTGCCAAAGGCCTACCCAGAGCACA
ATTGCGCGATAACACTCTTTCACGCGCACGATTTGATTTTCGATGGCATGATCAATTCAACCTTTCTCTTGATCCAGATA
CAGCCCGCGCCTTTCATGATGAGACAATGCCTAAAGAAGCTCATAAATTAGCGCATTTTTGTTCTATGTGTGGGCCTAAA
TTTTGCTCAATGCGTATTTCCCACGATATCCGTGATGCAGTGGCAATAAAAAAAACAAGAGACGAAGGCATGGCTGCTAT
GGCCGAAAAGTATCAACAAAATGGTGATCTCTATATGAAAGTCATGCCTTCTATAAAAGAAACAGTAGACGATTGA

Protein sequence :
MQKHTPSVSCSPFPSSHKFYQQSLLFPNVRVPLRKILLTDGSGESPFNVYDTSGPYTDENVIIDITKGLPAIRIPWLSER
ADTESYPARLVKPEDNGFTHGKDLTPVFEKKRPILRSKNGKSITQMTYARAGIITAEMEYVAIRENEGLIEKNKQHTTSS
KAFDASIPEVYTAEFVRNEIACGRAIIPQNINHPECEPMIIGRNFRVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTV
MDLSTGRNIHNIREWIIRNSPVPIGTVPIYQALEKVHGIAENLTWDIFRDTLIEQAEQGVDYFTIHAGLKLAFIPLTIDR
TTGIVSRGGSIIAKWCLHHHKENFLYEHFDEICDIAHTYDVSLSLGDGLRPGSIADANDEAQFAELKTLGELTQIAWEKN
VQTMIEGPGHVPMHKIKENMDQQLALCNEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDK
NDVKTGVITYKIAAHAADLAKGLPRAQLRDNTLSRARFDFRWHDQFNLSLDPDTARAFHDETMPKEAHKLAHFCSMCGPK
FCSMRISHDIRDAVAIKKTRDEGMAAMAEKYQQNGDLYMKVMPSIKETVDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 68
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 64