Gene Information

Name : guaA (BARBAKC583_0344)
Accession : YP_988663.1
Strain : Bartonella bacilliformis KC583
Genome accession: NC_008783
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 338944 - 340500 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGATACATCACATTCAGACACTGTTCTTATTATTGATTTTGGTTCACAAGTTACACAGCTGATAGCGAGGCGGGTACG
TGCAATGGGTGTTTATTCCGAAATTGTTCCTTTTCAATCGGCTTTAGGGGGAATCAATCGAATAAAGCCTAAAGCTGTTA
TTTTATCGGGTAGCCCTTATTCAACACTTGATAATGGTTCACCACGTGCTCCGATAGAAGTTTTTGAAGCTGGCATTCCA
GTTCTTGGTATTTGTTATGGTCAACAAGTTATGTGTGTTCAGCTTGGCGGAAAGGTGGAGGCTGGACATGAGCGTGAATT
TGGGCGTGCTTTTTTAGAGATAAAAGAAGAGAGTGCGCTTTTTGATGGTGTGTGGGAAAAAGGATCATCTCAACAAGTTT
GGATGAGTCATGGCGATCGCGTGACGGCTTTGCCGGAAGGTTTTTGTGTTATCGGAACATCAAAGGGTGCTCCTTATGCT
GCCATTTCTGATGAAAAGAGAAATTTTTATGCAGTGCAGTTTCATCCTGAAGTTGTTCATACACCAGATGGTGAAAAACT
TTTGCAAAATTTTGTCTGTAAAATATCTGGGATTAAAAATAATTGGTCAATGGCTGCTTATCGTGATCAGGCGATTGCTG
CAATACGTGAGAAAGTTGGCAAAAATCGCGTGATTTGCGGTCTTTCCGGTGGTGTTGATTCATCCGTTACAGCTGTATTG
CTTCATGAAGCAATAGGAGATCAACTGACGTGCATTTTTGTAGATCATGGGTTAATACGTAAAAATGAAGCAGAAGAAGT
TCTCAAATTATTCCGTGATAATTATAATATAGAGCTTATTCACGTTAATGCTGCTGATATGTTTATCAATGCGTTGGAAG
GTGAAACAGATCCAGAGAAAAAACGCAAAACAATTGGTCGTCTTTTTATTGAGGTTTTTGAAGAAGAAACTAAAAAAATA
GGTGGTGCAAAGTTTTTAGCACAAGGAACGCTTTATCCAGATGTTATTGAAAGTGTTTCGGCTATTGGTGAAGCAATAAC
AATTAAAAGTCATCATAATGTGGGGGGATTGCCGGAACGGATGAATATGAAACTTGTGGAGCCGTTACGTGAGCTATTTA
AGGATGATGTCCGCTCCTTAGGGAGGGAATTAGGTTTGCCTGAAGAGTTTATTAAACGCCATCCTTTCCCAGGACCTGGT
TTAGCAATTCGGTGTCCAGGTGCGGTTACGCGTGAAAAAATAGAAATTTTGCGTGAAGCAGATGCTATTTATCTTGATGA
AATCCGTAAAGCTGGGCTTTATGATAAAATTTGGCAAGCCTTTGCTATTCTTCTTCCTGTTCAAACTGTTGGTGTTATGG
GGGATGGACGCACTTATGAGTTTGTTTGTGCTCTTCGTGCCGTGACATCTGTAGATGGTATGACTGCTGATTTTTATCCG
CACGATATGGATTTTTTAAGCAGGACAGCAGCCCGTATTATTAATGAAGTTCGGGGCATCAATCGTGTTGTCTATGATAT
AACTTCAAAGCCTCCTGGCACCATTGAGTGGGAATGA

Protein sequence :
MDTSHSDTVLIIDFGSQVTQLIARRVRAMGVYSEIVPFQSALGGINRIKPKAVILSGSPYSTLDNGSPRAPIEVFEAGIP
VLGICYGQQVMCVQLGGKVEAGHEREFGRAFLEIKEESALFDGVWEKGSSQQVWMSHGDRVTALPEGFCVIGTSKGAPYA
AISDEKRNFYAVQFHPEVVHTPDGEKLLQNFVCKISGIKNNWSMAAYRDQAIAAIREKVGKNRVICGLSGGVDSSVTAVL
LHEAIGDQLTCIFVDHGLIRKNEAEEVLKLFRDNYNIELIHVNAADMFINALEGETDPEKKRKTIGRLFIEVFEEETKKI
GGAKFLAQGTLYPDVIESVSAIGEAITIKSHHNVGGLPERMNMKLVEPLRELFKDDVRSLGRELGLPEEFIKRHPFPGPG
LAIRCPGAVTREKIEILREADAIYLDEIRKAGLYDKIWQAFAILLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYP
HDMDFLSRTAARIINEVRGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-138 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-138 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-138 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-116 49